• Reference Citation Analysis
  • v
  • v
  • Find an Article
Find an Article PDF (4834263)   Today's Articles (5723)
For: Shin SY, Fauman EB, Petersen AK, Krumsiek J, Santos R, Huang J, Arnold M, Erte I, Forgetta V, Yang TP, Walter K, Menni C, Chen L, Vasquez L, Valdes AM, Hyde CL, Wang V, Ziemek D, Roberts P, Xi L, Grundberg E, The Multiple Tissue Human Expression Resource (MuTHER) Consortium, Waldenberger M, Richards JB, Mohney RP, Milburn MV, John SL, Trimmer J, Theis FJ, Overington JP, Suhre K, Brosnan MJ, Gieger C, Kastenmüller G, Spector TD, Soranzo N. An atlas of genetic influences on human blood metabolites. Nat Genet 2014;46:543-550. [PMID: 24816252 PMCID: PMC4064254 DOI: 10.1038/ng.2982] [Citation(s) in RCA: 1080] [Impact Index Per Article: 98.2] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/07/2013] [Accepted: 04/14/2014] [Indexed: 02/07/2023]
Number Cited by Other Article(s)
1
He J, Li L, Hu H. Causal associations between circulating metabolites and chronic kidney disease: a Mendelian randomization study. Ren Fail 2025;47:2498090. [PMID: 40302304 PMCID: PMC12044913 DOI: 10.1080/0886022x.2025.2498090] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/08/2024] [Revised: 03/30/2025] [Accepted: 04/13/2025] [Indexed: 05/02/2025]  Open
2
Su T, Xia Y. A quantitative comparison of the deleteriousness of missense and nonsense mutations using the structurally resolved human protein interactome. Protein Sci 2025;34:e70155. [PMID: 40384578 PMCID: PMC12086521 DOI: 10.1002/pro.70155] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/08/2025] [Revised: 04/02/2025] [Accepted: 04/22/2025] [Indexed: 05/20/2025]
3
Gao S, Xiao AY, Zou S, Li T, Deng H, Wang Y. Exploring causal links in the gut-brain axis: a Mendelian randomization study of gut microbiota, metabolites, and cognition. Food Funct 2025. [PMID: 40423497 DOI: 10.1039/d4fo04366a] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 05/28/2025]
4
MULTI consortium, Anagnostakis F, Ko S, Saadatinia M, Wang J, Davatzikos C, Wen J. Multi-organ metabolome biological age implicates cardiometabolic conditions and mortality risk. Nat Commun 2025;16:4871. [PMID: 40419465 DOI: 10.1038/s41467-025-59964-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Collaborators] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/09/2025] [Accepted: 05/06/2025] [Indexed: 05/28/2025]  Open
5
Pang ZY, Zhu YB, Hu JX, Li XX, Gao YJ, Wang YY, Zhou Q, Li P. The impact of lipidome on intervertebral disk degeneration, low back pain, and sciatica: a Mendelian randomization study. Sci Rep 2025;15:18045. [PMID: 40410311 PMCID: PMC12102376 DOI: 10.1038/s41598-025-99914-9] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/27/2024] [Accepted: 04/23/2025] [Indexed: 05/25/2025]  Open
6
Zhang X, Zhu Z, Shen C, Tang G. The causal effects of systemic antioxidant capacity on male infertility: A two-sample mendelian randomization analysis. Sci Rep 2025;15:17009. [PMID: 40379801 PMCID: PMC12084361 DOI: 10.1038/s41598-025-02243-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/11/2024] [Accepted: 05/12/2025] [Indexed: 05/19/2025]  Open
7
Lin S, Zhou D, Zhu H, Huang G, Yu M, Chen S, Wang J, Xia W. Genetic association between coffee consumption and multiple myeloma mediated by plasma metabolites: a Mendelian randomization study. Food Funct 2025. [PMID: 40375831 DOI: 10.1039/d4fo05696e] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 05/18/2025]
8
Yu K, Estonian Biobank Research Team, Estrada K, Esko T, Kals M, Nikopensius T, Kronberg J, Võsa U, Wuster A, Bomba L. Plasma Metabolic Outliers Identified in Estonian Human Knockouts. Metabolites 2025;15:323. [PMID: 40422899 DOI: 10.3390/metabo15050323] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/14/2025] [Revised: 05/02/2025] [Accepted: 05/07/2025] [Indexed: 05/28/2025]  Open
9
Liu Q, Shi R, Gu Y, Zhang J, Wang S, Xu T, Zhang Z, Tian J. The role of immune cell phenotypes and metabolites in the risk of ischemic stroke: a Mendelian randomization-based mediation analysis. BMC Neurol 2025;25:196. [PMID: 40329249 PMCID: PMC12054204 DOI: 10.1186/s12883-025-04205-5] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/19/2024] [Accepted: 04/23/2025] [Indexed: 05/08/2025]  Open
10
Cheng Y, Ruan X, Lu X, Yang Y, Wang Y, Yan S, Sun Y, Yan F, Jiang L, Liu T. Accounting for the impact of rare variants on causal inference with RARE: a novel multivariable Mendelian randomization method. Brief Bioinform 2025;26:bbaf214. [PMID: 40370099 PMCID: PMC12078940 DOI: 10.1093/bib/bbaf214] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/11/2024] [Revised: 04/10/2025] [Accepted: 04/20/2025] [Indexed: 05/16/2025]  Open
11
Chen B, Pu B, Lin S, Li S, Dong H. Investigating the association between polyunsaturated fatty acids and osteomyelitis by Mendelian randomization. Sci Rep 2025;15:14760. [PMID: 40295609 PMCID: PMC12037996 DOI: 10.1038/s41598-025-98502-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/29/2024] [Accepted: 04/11/2025] [Indexed: 04/30/2025]  Open
12
Yuan W, Liu Y, Liu C, Qiu Y. Serum metabolites and risk of sudden sensorineural hearing loss: A Mendelian randomization study. Braz J Otorhinolaryngol 2025;91:101596. [PMID: 40288303 PMCID: PMC12056394 DOI: 10.1016/j.bjorl.2025.101596] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/18/2024] [Revised: 02/05/2025] [Accepted: 03/10/2025] [Indexed: 04/29/2025]  Open
13
Cheng C, Liu Y, Sun L, Fan J, Sun X, Zheng JS, Zheng L, Zhu Y, Zhou D. Integrative metabolomics and genomics reveal molecular signatures for type 2 diabetes and its cardiovascular complications. Cardiovasc Diabetol 2025;24:166. [PMID: 40241080 PMCID: PMC12004867 DOI: 10.1186/s12933-025-02718-4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/17/2025] [Accepted: 03/29/2025] [Indexed: 04/18/2025]  Open
14
Beer SA, Went M, Mills C, Wood C, Sud A, Allan JM, Houlston R, Kaiser MF. Mendelian randomization of immune cell phenotypes to discover potential drug targets for B-cell malignancy. Blood Cancer J 2025;15:62. [PMID: 40199857 PMCID: PMC11979003 DOI: 10.1038/s41408-025-01277-x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/28/2024] [Revised: 03/28/2025] [Accepted: 04/01/2025] [Indexed: 04/10/2025]  Open
15
Lin C, Xia M, Dai Y, Huang Q, Sun Z, Zhang G, Luo R, Peng Q, Li J, Wang X, Lin H, Gao X, Tang H, Shen X, Wang S, Jin L, Hao X, Zheng Y. Cross-ancestry analyses of Chinese and European populations reveal insights into the genetic architecture and disease implication of metabolites. CELL GENOMICS 2025;5:100810. [PMID: 40118068 PMCID: PMC12008806 DOI: 10.1016/j.xgen.2025.100810] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 09/25/2024] [Revised: 01/22/2025] [Accepted: 02/17/2025] [Indexed: 03/23/2025]
16
Wang Z, Zhao C, Wang Z, Li M, Zhang L, Diao J, Chen J, Zhang L, Wang Y, Li M, Zhou Y, Xu H. Elucidating Causal Relationships Among Gut Microbiota, Human Blood Metabolites, and Knee Osteoarthritis: Evidence from a Two-Stage Mendelian Randomization Analysis. Rejuvenation Res 2025. [PMID: 40193247 DOI: 10.1089/rej.2024.0079] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 04/09/2025]  Open
17
Zhao Y, Zheng R, Luo K, Zhao H, Xiang W. Association between erythritol and lung cancer: a two-sample Mendelian randomization study. Nutr Metab (Lond) 2025;22:28. [PMID: 40197329 PMCID: PMC11978034 DOI: 10.1186/s12986-025-00916-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/09/2024] [Accepted: 03/14/2025] [Indexed: 04/10/2025]  Open
18
Yu X, Chen Y, Lei L, Li P, Lin D, Shen Y, Hou C, Chen J, Fan Y, Jin Y, Lu H, Wu D, Xu Y. Mendelian randomization analysis of blood metabolites and immune cell mediators in relation to GVHD and relapse. BMC Med 2025;23:201. [PMID: 40189523 PMCID: PMC11974087 DOI: 10.1186/s12916-025-04026-w] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/03/2024] [Accepted: 03/19/2025] [Indexed: 04/09/2025]  Open
19
Zheng Z, Sun H, Zhang P, Cao F, Xiao X, Zhao T. Causal relationship between gut microbiota, metabolites, and short stature: a Mendelian randomization study. Pediatr Res 2025:10.1038/s41390-025-03985-3. [PMID: 40181144 DOI: 10.1038/s41390-025-03985-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 08/26/2024] [Revised: 01/22/2025] [Accepted: 02/02/2025] [Indexed: 04/05/2025]
20
Zhao Q, Baranova A, Liu D, Cao H, Zhang F. Bidirectional causal associations between plasma metabolites and bipolar disorder. Mol Psychiatry 2025:10.1038/s41380-025-02977-3. [PMID: 40169804 DOI: 10.1038/s41380-025-02977-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/24/2024] [Revised: 03/03/2025] [Accepted: 03/21/2025] [Indexed: 04/03/2025]
21
Hu W, Hu Y, Li J, Men Y, Xia J, Zheng W, Zhao Y. Effect of L-Carnitine Level on the Risk of Neuromyelitis Optica Spectrum Disorders: A Two-Sample Mendelian Randomization Study. Mol Neurobiol 2025;62:5133-5142. [PMID: 39514170 DOI: 10.1007/s12035-024-04607-5] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/16/2023] [Accepted: 10/29/2024] [Indexed: 11/16/2024]
22
Zhan C, Quan Z, Huang X, Bu J, Li S. Causal relationships of circulating amino acids with sarcopenia-related traits: A bidirectional Mendelian randomization study. Clin Nutr 2025;47:258-264. [PMID: 40073510 DOI: 10.1016/j.clnu.2025.02.020] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/11/2024] [Revised: 01/26/2025] [Accepted: 02/16/2025] [Indexed: 03/14/2025]
23
Zhang R, Han L, Pu L, Jiang G, Guan Q, Fan W, Liu H. Investigating causal associations of gut microbiota and blood metabolites on stroke and its subtypes: A Mendelian randomization study. J Stroke Cerebrovasc Dis 2025;34:108233. [PMID: 39798630 DOI: 10.1016/j.jstrokecerebrovasdis.2025.108233] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/29/2024] [Revised: 01/07/2025] [Accepted: 01/08/2025] [Indexed: 01/15/2025]  Open
24
Ottensmann L, Tabassum R, Ruotsalainen SE, Gerl MJ, Klose C, McCartney DL, Widén E, Simons K, Ripatti S, Vitart V, Hayward C, Pirinen M. Examining the link between 179 lipid species and 7 diseases using genetic predictors. EBioMedicine 2025;114:105671. [PMID: 40157129 PMCID: PMC11995710 DOI: 10.1016/j.ebiom.2025.105671] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/05/2024] [Revised: 03/12/2025] [Accepted: 03/13/2025] [Indexed: 04/01/2025]  Open
25
Xu Q, Liu S, Ran X, Li Y, Shen J, Tang H, Liu JK, Pan G, Zhang Q. Robust Sensory Information Reconstruction and Classification With Augmented Spikes. IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS 2025;36:7462-7471. [PMID: 38833393 DOI: 10.1109/tnnls.2024.3404021] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 06/06/2024]
26
Peng P, Shen F, Peng B, Chen Z, Zhou L, Hao X, Liu Y. Genetic Evidence Supporting the Repurposing of mTOR Inhibitors for Reducing BMI. Biomedicines 2025;13:839. [PMID: 40299431 PMCID: PMC12025023 DOI: 10.3390/biomedicines13040839] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/10/2025] [Revised: 03/26/2025] [Accepted: 03/28/2025] [Indexed: 04/30/2025]  Open
27
Yin X, Li J, Bose D, Okamoto J, Kwon A, Jackson AU, Fernandes Silva L, Oravilahti A, Chu X, Stringham HM, Liu L, Peng R, Xia Z, Ripatti S, Daly M, Palotie A, Scott LJ, Burant CF, Fauman EB, Wen X, Boehnke M, Laakso M, Morrison J. Assessing the potential causal effects of 1099 plasma metabolites on 2099 binary disease endpoints. Nat Commun 2025;16:3039. [PMID: 40155430 PMCID: PMC11953310 DOI: 10.1038/s41467-025-58129-2] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/19/2023] [Accepted: 03/10/2025] [Indexed: 04/01/2025]  Open
28
Yang R, Lv M, Yang X, Zhai S. A Mendelian randomized study of circulating antioxidants in the diet and risk of cardiovascular disease. Sci Rep 2025;15:10341. [PMID: 40133449 PMCID: PMC11937293 DOI: 10.1038/s41598-025-94369-4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/03/2024] [Accepted: 03/13/2025] [Indexed: 03/27/2025]  Open
29
Qi L, Zhang C, Liu Y, Li W, Ren J, Zhao M. Plasma proteomes and metabolism with genome-wide association data for causal effect identification in ovarian cancer. Discov Oncol 2025;16:388. [PMID: 40131661 PMCID: PMC11936866 DOI: 10.1007/s12672-025-02087-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 12/05/2024] [Accepted: 03/06/2025] [Indexed: 03/27/2025]  Open
30
Meng XY, Zhu YQ, Zhang YJ, Sun W, Li SA. Causal relationships between serum metabolites and coronary heart disease risk: a mendelian randomization study. Front Genet 2025;16:1440364. [PMID: 40182922 PMCID: PMC11965349 DOI: 10.3389/fgene.2025.1440364] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/29/2024] [Accepted: 02/21/2025] [Indexed: 04/05/2025]  Open
31
Zhang L, Li Y, Pu Y, Dang T, Shi Q, Wu W. Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne. Eur J Nutr 2025;64:130. [PMID: 40106045 DOI: 10.1007/s00394-025-03647-4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/08/2024] [Accepted: 03/05/2025] [Indexed: 03/22/2025]
32
Mori Y, van Dijk EHC, Miyake M, Hosoda Y, den Hollander AI, Yzer S, Miki A, Chen LJ, Ahn J, Takahashi A, Morino K, Nakao SY, Hoyng CB, Ng DSC, Cen LP, Chen H, Ng TK, Pang CP, Joo K, Sato T, Sakata Y, Tajima A, Tabara Y, Park KH, Matsuda F, Yamashiro K, Honda S, Nagasaki M, Boon CJF, Tsujikawa A. Genome-wide association and multi-omics analyses provide insights into the disease mechanisms of central serous chorioretinopathy. Sci Rep 2025;15:9158. [PMID: 40097481 PMCID: PMC11914043 DOI: 10.1038/s41598-025-92210-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/23/2024] [Accepted: 02/26/2025] [Indexed: 03/19/2025]  Open
33
Eissman JM, Qiao M, Kalia V, Zerlin-Esteves M, Reyes-Dumeyer D, Piriz A, Dubey S, Nandakumar R, Lee AJ, Lantigua RA, Medrano M, Mejia DR, Honig LS, Dalgard CL, Miller GW, Mayeux R, Vardarajan BN. Genetic Regulation of the Metabolome Differs by Sex, Alzheimer's Disease Stage, and Plasma Biomarker Status. MEDRXIV : THE PREPRINT SERVER FOR HEALTH SCIENCES 2025:2025.02.26.25322932. [PMID: 40061336 PMCID: PMC11888523 DOI: 10.1101/2025.02.26.25322932] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Grants] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Indexed: 03/18/2025]
34
Li Y, Chen Z, Huang Z, Wang J, Wang J, Lin L, Lin R, Lai J, Zhang L, Qiu S. Causal association between blood metabolites and head and neck cancer: butyrylcarnitine identified as an associated trait for cancer risk and progression. Hereditas 2025;162:36. [PMID: 40087718 PMCID: PMC11907814 DOI: 10.1186/s41065-025-00408-5] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/05/2024] [Accepted: 03/05/2025] [Indexed: 03/17/2025]  Open
35
Bovo S, Ribani A, Fanelli F, Galimberti G, Martelli PL, Trevisi P, Bertolini F, Bolner M, Casadio R, Dall'Olio S, Gallo M, Luise D, Mazzoni G, Schiavo G, Taurisano V, Zambonelli P, Bosi P, Pagotto U, Fontanesi L. Merging metabolomics and genomics provides a catalog of genetic factors that influence molecular phenotypes in pigs linking relevant metabolic pathways. Genet Sel Evol 2025;57:11. [PMID: 40050712 PMCID: PMC11887101 DOI: 10.1186/s12711-025-00960-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/21/2024] [Accepted: 02/18/2025] [Indexed: 03/09/2025]  Open
36
Wei P, Gao S, Han G. Evidence for Genetic Causal Association Between the Gut Microbiome, Derived Metabolites, and Age-Related Macular Degeneration: A Mediation Mendelian Randomization Analysis. Biomedicines 2025;13:639. [PMID: 40149615 PMCID: PMC11940807 DOI: 10.3390/biomedicines13030639] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/24/2025] [Revised: 02/25/2025] [Accepted: 03/03/2025] [Indexed: 03/29/2025]  Open
37
Hector EC, Zhang D, Tian L, Feng J, Yin X, Xu T, Laakso M, Bai Y, Xiao J, Kang J, Yu T. Dissecting genetic regulation of metabolic coordination. Brief Bioinform 2025;26:bbaf095. [PMID: 40067114 PMCID: PMC11894804 DOI: 10.1093/bib/bbaf095] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/30/2024] [Revised: 12/24/2024] [Accepted: 02/19/2025] [Indexed: 03/15/2025]  Open
38
Shen J, Guo Y, Cao R. The relationship between amino acids and gastroesophageal reflux disease: evidence from a mendelian randomization analysis combined with a meta-analysis. Front Immunol 2025;16:1420132. [PMID: 40103821 PMCID: PMC11914792 DOI: 10.3389/fimmu.2025.1420132] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/19/2024] [Accepted: 02/06/2025] [Indexed: 03/20/2025]  Open
39
Ning L, Gao Z, Chen D, Han J, Xie G, Sun J. Causality of blood metabolites on hepatocellular carcinoma and cholangiocarcinoma: a metabolome-wide mendelian randomization study. BMC Cancer 2025;25:389. [PMID: 40038628 PMCID: PMC11877886 DOI: 10.1186/s12885-025-13690-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/29/2023] [Accepted: 02/07/2025] [Indexed: 03/06/2025]  Open
40
Du Z, Liu X, Xie Z, Wang Q, Lv Z, Li L, Wang H, Xue D, Zhang Y. The relationship between a high-fat diet, gut microbiome, and systemic chronic inflammation: insights from integrated multiomics analysis. Am J Clin Nutr 2025;121:643-653. [PMID: 39746397 DOI: 10.1016/j.ajcnut.2024.12.026] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/26/2024] [Revised: 10/29/2024] [Accepted: 12/26/2024] [Indexed: 01/04/2025]  Open
41
Geng W, Wen X, Jin R, Yuan X. 1,400 genetically predicted plasma metabolites in relation to risk of primary biliary cholangitis: a bi-directional, two-sample Mendelian randomization analysis. Clin Exp Hepatol 2025;11:61-70. [PMID: 40303583 PMCID: PMC12035705 DOI: 10.5114/ceh.2025.148221] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 08/06/2024] [Accepted: 11/01/2024] [Indexed: 05/02/2025]  Open
42
Mi Y, Lin S, Chen K, Shu Z. The causal association between plasma caffeine and frailty: A two-sample mendelian randomization study. Arch Gerontol Geriatr 2025;130:105706. [PMID: 39616874 DOI: 10.1016/j.archger.2024.105706] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/06/2024] [Revised: 10/24/2024] [Accepted: 11/25/2024] [Indexed: 01/11/2025]
43
Colenso‐Semple LM, McKendry J, Lim C, Atherton PJ, Wilkinson DJ, Smith K, Phillips SM. Menstrual cycle phase does not influence muscle protein synthesis or whole-body myofibrillar proteolysis in response to resistance exercise. J Physiol 2025;603:1109-1121. [PMID: 39630025 PMCID: PMC11870050 DOI: 10.1113/jp287342] [Citation(s) in RCA: 1] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/19/2024] [Accepted: 10/24/2024] [Indexed: 03/01/2025]  Open
44
Wei Y, Huang L, Sui J, Liu C, Qi M. Human blood metabolites and risk of post-traumatic stress disorder: A Mendelian randomization study. J Affect Disord 2025;372:227-233. [PMID: 39643216 DOI: 10.1016/j.jad.2024.12.029] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/29/2024] [Revised: 11/30/2024] [Accepted: 12/03/2024] [Indexed: 12/09/2024]
45
Reus LM, Boltz T, Francia M, Bot M, Ramesh N, Koromina M, Pijnenburg YAL, den Braber A, van der Flier WM, Visser PJ, van der Lee SJ, Tijms BM, Teunissen CE, Loohuis LO, Ophoff RA. Quantitative trait loci mapping of circulating metabolites in cerebrospinal fluid to uncover biological mechanisms involved in brain-related phenotypes. Mol Psychiatry 2025:10.1038/s41380-025-02934-0. [PMID: 40021830 DOI: 10.1038/s41380-025-02934-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/07/2023] [Revised: 12/16/2024] [Accepted: 02/12/2025] [Indexed: 03/03/2025]
46
Arnold M, Buyukozkan M, Doraiswamy PM, Nho K, Wu T, Gudnason V, Launer LJ, Wang-Sattler R, Adamski J, De Jager PL, Ertekin-Taner N, Bennett DA, Saykin AJ, Peters A, Suhre K, Kaddurah-Daouk R, Kastenmüller G, Krumsiek J. Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease. Nat Commun 2025;16:1910. [PMID: 39994231 PMCID: PMC11850607 DOI: 10.1038/s41467-025-57032-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/19/2023] [Accepted: 02/04/2025] [Indexed: 02/26/2025]  Open
47
Bender A, Ranea-Robles P, Williams EG, Mirzaian M, Heimel JA, Levelt CN, Wanders RJ, Aerts JM, Zhu J, Auwerx J, Houten SM, Argmann CA. A multiomic network approach uncovers disease modifying mechanisms of inborn errors of metabolism. BIORXIV : THE PREPRINT SERVER FOR BIOLOGY 2025:2025.02.19.639093. [PMID: 40027804 PMCID: PMC11870498 DOI: 10.1101/2025.02.19.639093] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Subscribe] [Scholar Register] [Indexed: 03/05/2025]
48
Huang M, Xing F, Hu Y, Sun F, Zhang C, Xv Z, Yang Y, Deng Q, Shi R, Li L, Zhu J, Xu F, Li D, Wang J. Causal inference study of plasma proteins and blood metabolites mediating the effect of obesity-related indicators on osteoporosis. Front Endocrinol (Lausanne) 2025;16:1435295. [PMID: 40041284 PMCID: PMC11876022 DOI: 10.3389/fendo.2025.1435295] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 05/20/2024] [Accepted: 01/21/2025] [Indexed: 03/06/2025]  Open
49
Sheng Q, Ma Y, Geng B, Chen J, Cheng J, Liu S, Li R, Li X, Wang J, Lu H, Gao F, Gao F. Serum amino acid alterations in hyperuricemia: potential targets for renal disease prevention. Amino Acids 2025;57:16. [PMID: 39966264 PMCID: PMC11836093 DOI: 10.1007/s00726-025-03444-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/16/2024] [Accepted: 01/30/2025] [Indexed: 02/20/2025]
50
Cheng C, Xu F, Pan XF, Wang C, Fan J, Yang Y, Liu Y, Sun L, Liu X, Xu Y, Zhou Y, Xiao C, Gou W, Miao Z, Yuan J, Shen L, Fu Y, Sun X, Zhu Y, Chen Y, Pan A, Zhou D, Zheng JS. Genetic mapping of serum metabolome to chronic diseases among Han Chinese. CELL GENOMICS 2025;5:100743. [PMID: 39837327 PMCID: PMC11872534 DOI: 10.1016/j.xgen.2024.100743] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 05/01/2024] [Revised: 10/31/2024] [Accepted: 12/24/2024] [Indexed: 01/23/2025]
PrevPage 1 of 22 123452122Next
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Excel