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For: Dara L, Johnson H, Suda J, Win S, Gaarde W, Han D, Kaplowitz N. Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis. Hepatology. 2015;62:1847-1857. [PMID: 26077809 DOI: 10.1002/hep.27939] [Cited by in Crossref: 101] [Cited by in F6Publishing: 100] [Article Influence: 16.8] [Reference Citation Analysis]
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2 Tovey Crutchfield EC, Garnish SE, Hildebrand JM. The Role of the Key Effector of Necroptotic Cell Death, MLKL, in Mouse Models of Disease. Biomolecules 2021;11:803. [PMID: 34071602 DOI: 10.3390/biom11060803] [Reference Citation Analysis]
3 Dara L, Kaplowitz N. The many faces of RIPK3: What about NASH? Hepatology 2016;64:1411-3. [PMID: 27338154 DOI: 10.1002/hep.28700] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.8] [Reference Citation Analysis]
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7 Han Y, Black S, Gong Z, Chen Z, Ko JK, Zhou Z, Xia T, Fang D, Yang D, Gu D, Zhang Z, Ren H, Duan X, Reader BF, Chen P, Li Y, Kim JL, Li Z, Xu X, Guo L, Zhou X, Haggard E, Zhu H, Tan T, Chen K, Ma J, Zeng C. Membrane-delimited signaling and cytosolic action of MG53 preserve hepatocyte integrity during drug-induced liver injury. J Hepatol 2021:S0168-8278(21)02154-1. [PMID: 34736969 DOI: 10.1016/j.jhep.2021.10.017] [Reference Citation Analysis]
8 Cubero FJ, Zoubek ME, Hu W, Peng J, Zhao G, Nevzorova YA, Al Masaoudi M, Bechmann LP, Boekschoten MV, Muller M. Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury. Gastroenterology. 2016;150:968-981. [PMID: 26708719 DOI: 10.1053/j.gastro.2015.12.019] [Cited by in Crossref: 55] [Cited by in F6Publishing: 50] [Article Influence: 9.2] [Reference Citation Analysis]
9 Yi Y, Zhang W, Tao L, Shao Q, Xu Q, Chen Y, Zhang H, Zhang J, Weng D. RIP1 kinase inactivation protects against acetaminophen-induced acute liver injury in mice. Free Radic Biol Med 2021;174:57-65. [PMID: 34324981 DOI: 10.1016/j.freeradbiomed.2021.07.034] [Reference Citation Analysis]
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11 Günther C, He GW, Kremer AE, Murphy JM, Petrie EJ, Amann K, Vandenabeele P, Linkermann A, Poremba C, Schleicher U, Dewitz C, Krautwald S, Neurath MF, Becker C, Wirtz S. The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis. J Clin Invest 2016;126:4346-60. [PMID: 27756058 DOI: 10.1172/JCI87545] [Cited by in Crossref: 84] [Cited by in F6Publishing: 55] [Article Influence: 16.8] [Reference Citation Analysis]
12 Bolognese AC, Yang WL, Hansen LW, Denning NL, Nicastro JM, Coppa GF, Wang P. Inhibition of necroptosis attenuates lung injury and improves survival in neonatal sepsis. Surgery 2018:S0039-6060(18)30096-5. [PMID: 29709367 DOI: 10.1016/j.surg.2018.02.017] [Cited by in Crossref: 11] [Cited by in F6Publishing: 13] [Article Influence: 3.7] [Reference Citation Analysis]
13 Andrade RJ, Chalasani N, Björnsson ES, Suzuki A, Kullak-Ublick GA, Watkins PB, Devarbhavi H, Merz M, Lucena MI, Kaplowitz N, Aithal GP. Drug-induced liver injury. Nat Rev Dis Primers 2019;5:58. [PMID: 31439850 DOI: 10.1038/s41572-019-0105-0] [Cited by in Crossref: 81] [Cited by in F6Publishing: 78] [Article Influence: 40.5] [Reference Citation Analysis]
14 Spinnenhirn V, Demgenski J, Brunner T. Death Receptor Interactions With the Mitochondrial Cell Death Pathway During Immune Cell-, Drug- and Toxin-Induced Liver Damage. Front Cell Dev Biol 2019;7:72. [PMID: 31069226 DOI: 10.3389/fcell.2019.00072] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
15 Xu N, Meng H, Liu T, Feng Y, Qi Y, Zhang D, Wang H. Sterol O-acyltransferase 1 deficiency improves defective insulin signaling in the brains of mice fed a high-fat diet. Biochemical and Biophysical Research Communications 2018;499:105-11. [DOI: 10.1016/j.bbrc.2018.02.122] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 1.3] [Reference Citation Analysis]
16 Ramachandran A, Jaeschke H. Acetaminophen Toxicity: Novel Insights Into Mechanisms and Future Perspectives. Gene Expr 2018;18:19-30. [PMID: 29054140 DOI: 10.3727/105221617X15084371374138] [Cited by in Crossref: 58] [Cited by in F6Publishing: 37] [Article Influence: 14.5] [Reference Citation Analysis]
17 Krishna-Subramanian S, Singer S, Armaka M, Banales JM, Holzer K, Schirmacher P, Walczak H, Kollias G, Pasparakis M, Kondylis V. RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury. Cell Death Differ 2019;26:2710-26. [PMID: 30988397 DOI: 10.1038/s41418-019-0330-9] [Cited by in Crossref: 9] [Cited by in F6Publishing: 10] [Article Influence: 4.5] [Reference Citation Analysis]
18 Jaeschke H, Adelusi OB, Ramachandran A. Ferroptosis and Acetaminophen Hepatotoxicity: Are We Going Down Another Rabbit Hole? Gene Expr 2021;20:169-78. [PMID: 33441220 DOI: 10.3727/105221621X16104581979144] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 5.0] [Reference Citation Analysis]
19 Koppe C, Verheugd P, Gautheron J, Reisinger F, Kreggenwinkel K, Roderburg C, Quagliata L, Terracciano L, Gassler N, Tolba RH, Boege Y, Weber A, Karin M, Luedde M, Neumann UP, Weiskirchen R, Tacke F, Vucur M, Trautwein C, Lüscher B, Preisinger C, Heikenwalder M, Luedde T. IκB kinaseα/β control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell-death mediator receptor-interacting protein kinase 1. Hepatology 2016;64:1217-31. [PMID: 27396433 DOI: 10.1002/hep.28723] [Cited by in Crossref: 36] [Cited by in F6Publishing: 38] [Article Influence: 7.2] [Reference Citation Analysis]
20 Blériot C, Lecuit M. RIPK1, a key survival factor for hepatocytes. J Hepatol 2017;66:1118-9. [PMID: 28215597 DOI: 10.1016/j.jhep.2017.02.009] [Cited by in Crossref: 2] [Cited by in F6Publishing: 3] [Article Influence: 0.5] [Reference Citation Analysis]
21 Siempos II, Ma KC, Imamura M, Baron RM, Fredenburgh LE, Huh JW, Moon JS, Finkelsztein EJ, Jones DS, Lizardi MT, Schenck EJ, Ryter SW, Nakahira K, Choi AM. RIPK3 mediates pathogenesis of experimental ventilator-induced lung injury. JCI Insight 2018;3:97102. [PMID: 29720570 DOI: 10.1172/jci.insight.97102] [Cited by in Crossref: 27] [Cited by in F6Publishing: 26] [Article Influence: 9.0] [Reference Citation Analysis]
22 Ni HM, McGill MR, Chao X, Woolbright BL, Jaeschke H, Ding WX. Caspase Inhibition Prevents Tumor Necrosis Factor-α-Induced Apoptosis and Promotes Necrotic Cell Death in Mouse Hepatocytes in Vivo and in Vitro. Am J Pathol 2016;186:2623-36. [PMID: 27616656 DOI: 10.1016/j.ajpath.2016.06.009] [Cited by in Crossref: 34] [Cited by in F6Publishing: 37] [Article Influence: 6.8] [Reference Citation Analysis]
23 Jaeschke H, Duan L, Akakpo JY, Farhood A, Ramachandran A. The role of apoptosis in acetaminophen hepatotoxicity. Food Chem Toxicol 2018;118:709-18. [PMID: 29920288 DOI: 10.1016/j.fct.2018.06.025] [Cited by in Crossref: 54] [Cited by in F6Publishing: 51] [Article Influence: 18.0] [Reference Citation Analysis]
24 Bai L, Kong M, Duan Z, Liu S, Zheng S, Chen Y. M2-like macrophages exert hepatoprotection in acute-on-chronic liver failure through inhibiting necroptosis-S100A9-necroinflammation axis. Cell Death Dis 2021;12:93. [PMID: 33462187 DOI: 10.1038/s41419-020-03378-w] [Cited by in Crossref: 2] [Article Influence: 2.0] [Reference Citation Analysis]
25 Li L, Shan S, Kang K, Zhang C, Kou R, Song F. The cross-talk of NLRP3 inflammasome activation and necroptotic hepatocyte death in acetaminophen-induced mice acute liver injury. Hum Exp Toxicol 2021;40:673-84. [PMID: 33021112 DOI: 10.1177/0960327120961158] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
26 Saeed WK, Jun DW, Jang K, Chae YJ, Lee JS, Kang HT. Does necroptosis have a crucial role in hepatic ischemia-reperfusion injury? PLoS One. 2017;12:e0184752. [PMID: 28957350 DOI: 10.1371/journal.pone.0184752] [Cited by in Crossref: 16] [Cited by in F6Publishing: 16] [Article Influence: 4.0] [Reference Citation Analysis]
27 Kondylis V, Kumari S, Vlantis K, Pasparakis M. The interplay of IKK, NF-κB and RIPK1 signaling in the regulation of cell death, tissue homeostasis and inflammation. Immunol Rev 2017;277:113-27. [PMID: 28462531 DOI: 10.1111/imr.12550] [Cited by in Crossref: 88] [Cited by in F6Publishing: 80] [Article Influence: 29.3] [Reference Citation Analysis]
28 Lu J, Wang H, Zhang R, Wan Z, Gao H, Cai J, Cheng Y, Pu D, Lin T, Fan C, Sun Y. Effects of Photoperiod on Acetaminophen-Induced Hepatotoxicity in Mice. Dig Dis Sci 2020;65:178-88. [PMID: 31376085 DOI: 10.1007/s10620-019-05749-6] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
29 Zoubek ME, Woitok MM, Sydor S, Nelson LJ, Bechmann LP, Lucena MI, Andrade RJ, Bast A, Koek GH, Trautwein C, Cubero FJ. Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury. J Pathol 2019;247:110-22. [PMID: 30264435 DOI: 10.1002/path.5174] [Cited by in Crossref: 1] [Cited by in F6Publishing: 3] [Article Influence: 0.3] [Reference Citation Analysis]
30 Fernandez-Checa JC, Bagnaninchi P, Ye H, Sancho-Bru P, Falcon-Perez JM, Royo F, Garcia-Ruiz C, Konu O, Miranda J, Lunov O, Dejneka A, Elfick A, McDonald A, Sullivan GJ, Aithal G, Lucena MI, Andrade RJ, Fromenty B, Krannendonk M, Cubero FJ, Nelson LJ. ADVANCED PRECLINICAL MODELS FOR EVALUATION OF DRUG INDUCED LIVER INJURY - CONSENSUS STATEMENT BY THE EUROPEAN DRUG-INDUCED LIVER INJURY NETWORK [PRO-EURO-DILI-NET]. J Hepatol 2021:S0168-8278(21)00441-4. [PMID: 34171436 DOI: 10.1016/j.jhep.2021.06.021] [Cited by in Crossref: 1] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
31 Yamada N, Karasawa T, Kimura H, Watanabe S, Komada T, Kamata R, Sampilvanjil A, Ito J, Nakagawa K, Kuwata H, Hara S, Mizuta K, Sakuma Y, Sata N, Takahashi M. Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure. Cell Death Dis 2020;11:144. [PMID: 32094346 DOI: 10.1038/s41419-020-2334-2] [Cited by in Crossref: 35] [Cited by in F6Publishing: 35] [Article Influence: 35.0] [Reference Citation Analysis]
32 Vanden Berghe T, Hassannia B, Vandenabeele P. An outline of necrosome triggers. Cell Mol Life Sci 2016;73:2137-52. [PMID: 27052312 DOI: 10.1007/s00018-016-2189-y] [Cited by in Crossref: 65] [Cited by in F6Publishing: 61] [Article Influence: 13.0] [Reference Citation Analysis]
33 Dara L, Liu ZX, Kaplowitz N. A murder mystery in the liver: who done it and how? J Clin Invest 2016;126:4068-71. [PMID: 27760053 DOI: 10.1172/JCI90830] [Cited by in Crossref: 9] [Cited by in F6Publishing: 5] [Article Influence: 1.8] [Reference Citation Analysis]
34 Du K, Ramachandran A, Weemhoff JL, Woolbright BL, Jaeschke AH, Chao X, Ding WX, Jaeschke H. Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity. Arch Toxicol 2019;93:163-78. [PMID: 30324313 DOI: 10.1007/s00204-018-2331-8] [Cited by in Crossref: 25] [Cited by in F6Publishing: 25] [Article Influence: 8.3] [Reference Citation Analysis]
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36 Iorga A, Dara L, Kaplowitz N. Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis. Int J Mol Sci. 2017;18. [PMID: 28486401 DOI: 10.3390/ijms18051018] [Cited by in Crossref: 108] [Cited by in F6Publishing: 98] [Article Influence: 27.0] [Reference Citation Analysis]
37 Saeed WK, Jun DW, Jang K, Ahn SB, Oh JH, Chae YJ, Lee JS, Kang HT. Mismatched effects of receptor interacting protein kinase-3 on hepatic steatosis and inflammation in non-alcoholic fatty liver disease. World J Gastroenterol 2018; 24(48): 5477-5490 [PMID: 30622377 DOI: 10.3748/wjg.v24.i48.5477] [Cited by in CrossRef: 6] [Cited by in F6Publishing: 8] [Article Influence: 2.0] [Reference Citation Analysis]
38 Tsai M, Wang Y, Lai Y, Tsou H, Liou G, Ko J, Wang S. Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice. Toxicology Letters 2018;290:97-109. [DOI: 10.1016/j.toxlet.2018.03.024] [Cited by in Crossref: 49] [Cited by in F6Publishing: 46] [Article Influence: 16.3] [Reference Citation Analysis]
39 Verboom L, Martens A, Priem D, Hoste E, Sze M, Vikkula H, Van Hove L, Voet S, Roels J, Maelfait J, Bongiovanni L, de Bruin A, Scott CL, Saeys Y, Pasparakis M, Bertrand MJM, van Loo G. OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis. Cell Rep 2020;30:2237-2247.e6. [PMID: 32075762 DOI: 10.1016/j.celrep.2020.01.028] [Cited by in Crossref: 9] [Cited by in F6Publishing: 12] [Article Influence: 9.0] [Reference Citation Analysis]
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42 Oppelt A, Kaschek D, Huppelschoten S, Sison-Young R, Zhang F, Buck-Wiese M, Herrmann F, Malkusch S, Krüger CL, Meub M, Merkt B, Zimmermann L, Schofield A, Jones RP, Malik H, Schilling M, Heilemann M, van de Water B, Goldring CE, Park BK, Timmer J, Klingmüller U. Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds. NPJ Syst Biol Appl 2018;4:23. [PMID: 29900006 DOI: 10.1038/s41540-018-0058-z] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
43 Ni HM, Chao X, Kaseff J, Deng F, Wang S, Shi YH, Li T, Ding WX, Jaeschke H. Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)-Mixed Lineage Kinase Domain-Like Protein (MLKL)-Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers. Am J Pathol. 2019;189:1363-1374. [PMID: 31026418 DOI: 10.1016/j.ajpath.2019.03.010] [Cited by in Crossref: 20] [Cited by in F6Publishing: 23] [Article Influence: 10.0] [Reference Citation Analysis]
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45 Chen L, Cao Z, Yan L, Ding Y, Shen X, Liu K, Xiang X, Xie Q, Zhu C, Bao S, Wang H. Circulating Receptor-Interacting Protein Kinase 3 Are Increased in HBV Patients With Acute-on-Chronic Liver Failure and Are Associated With Clinical Outcome. Front Physiol 2020;11:526. [PMID: 32655398 DOI: 10.3389/fphys.2020.00526] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
46 Yan M, Ye L, Yin S, Lu X, Liu X, Lu S, Cui J, Fan L, Kaplowitz N, Hu H. Glycycoumarin protects mice against acetaminophen-induced liver injury predominantly via activating sustained autophagy. Br J Pharmacol 2018;175:3747-57. [PMID: 30024038 DOI: 10.1111/bph.14444] [Cited by in Crossref: 28] [Cited by in F6Publishing: 27] [Article Influence: 9.3] [Reference Citation Analysis]
47 Dara L, Liu ZX, Kaplowitz N. Questions and controversies: the role of necroptosis in liver disease. Cell Death Discov 2016;2:16089. [PMID: 27924226 DOI: 10.1038/cddiscovery.2016.89] [Cited by in Crossref: 44] [Cited by in F6Publishing: 44] [Article Influence: 8.8] [Reference Citation Analysis]
48 Du K, Ramachandran A, McGill MR, Mansouri A, Asselah T, Farhood A, Woolbright BL, Ding WX, Jaeschke H. Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity. Food Chem Toxicol 2017;108:339-50. [PMID: 28827156 DOI: 10.1016/j.fct.2017.08.020] [Cited by in Crossref: 37] [Cited by in F6Publishing: 37] [Article Influence: 9.3] [Reference Citation Analysis]
49 Chen D, Ni HM, Wang L, Ma X, Yu J, Ding WX, Zhang L. p53 Up-regulated Modulator of Apoptosis Induction Mediates Acetaminophen-Induced Necrosis and Liver Injury in Mice. Hepatology 2019;69:2164-79. [PMID: 30552702 DOI: 10.1002/hep.30422] [Cited by in Crossref: 18] [Cited by in F6Publishing: 19] [Article Influence: 9.0] [Reference Citation Analysis]
50 Zhang B, Li MD, Yin R, Liu Y, Yang Y, Mitchell-Richards KA, Nam JH, Li R, Wang L, Iwakiri Y, Chung D, Robert ME, Ehrlich BE, Bennett AM, Yu J, Nathanson MH, Yang X. O-GlcNAc transferase suppresses necroptosis and liver fibrosis. JCI Insight 2019;4:127709. [PMID: 31672932 DOI: 10.1172/jci.insight.127709] [Cited by in Crossref: 13] [Cited by in F6Publishing: 10] [Article Influence: 6.5] [Reference Citation Analysis]
51 McGill MR, Jaeschke H. Animal models of drug-induced liver injury. Biochim Biophys Acta Mol Basis Dis 2019;1865:1031-9. [PMID: 31007174 DOI: 10.1016/j.bbadis.2018.08.037] [Cited by in Crossref: 34] [Cited by in F6Publishing: 32] [Article Influence: 11.3] [Reference Citation Analysis]
52 Tao L, Lin H, Wen J, Sun Q, Gao Y, Xu X, Wang J, Zhang J, Weng D. The kinase receptor-interacting protein 1 is required for inflammasome activation induced by endoplasmic reticulum stress. Cell Death Dis 2018;9:641. [PMID: 29844315 DOI: 10.1038/s41419-018-0694-7] [Cited by in Crossref: 16] [Cited by in F6Publishing: 17] [Article Influence: 5.3] [Reference Citation Analysis]
53 Ramachandran A, Jaeschke H. Acetaminophen Hepatotoxicity. Semin Liver Dis 2019;39:221-34. [PMID: 30849782 DOI: 10.1055/s-0039-1679919] [Cited by in Crossref: 67] [Cited by in F6Publishing: 50] [Article Influence: 33.5] [Reference Citation Analysis]
54 Yan T, Wang H, Zhao M, Yagai T, Chai Y, Krausz KW, Xie C, Cheng X, Zhang J, Che Y, Li F, Wu Y, Brocker CN, Gonzalez FJ, Wang G, Hao H. Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α-Mediated Apoptosis. Drug Metab Dispos 2016;44:720-31. [PMID: 26965985 DOI: 10.1124/dmd.116.069419] [Cited by in Crossref: 32] [Cited by in F6Publishing: 29] [Article Influence: 6.4] [Reference Citation Analysis]
55 Lőrincz T, Deák V, Makk-Merczel K, Varga D, Hajdinák P, Szarka A. The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced Toxicity. Life (Basel) 2021;11:856. [PMID: 34440600 DOI: 10.3390/life11080856] [Reference Citation Analysis]
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