Academic Content and Language Evaluation of This Article
CrossCheck and Google Search of This Article
Academic Rules and Norms of This Article
Citation of this article
Corresponding Author of This Article
Research Domain of This Article
Article-Type of This Article
Open-Access Policy of This Article
Times Cited Counts in Google of This Article
Number of Hits and Downloads for This Article
- Total Article Views (19509)
All Articles published online
|
Featured Article
|
Publishing Process of This Article
|
Sep 18, 2017 (publication date) through Jul 25, 2025
Times Cited of This Article
Journal Information of This Article
Publication Name
World Journal of Hepatology
ISSN
1948-5182
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
| For: | Conway R, Carey JJ. Risk of liver disease in methotrexate treated patients. World J Hepatol 2017; 9(26): 1092-1100 [PMID: 28989565 DOI: 10.4254/wjh.v9.i26.1092] |
|---|---|
| URL: | https://www.wjgnet.com/1007-9327/full/v9/i26/1092.htm |
| Number | Citing Articles |
| 1 |
Liudmyla Parkhomenko, Larysa Strashok, Olga Pavlova. BASIC FIBROBLAST GROWTH FACTOR AND ADIPONECTIN IN ADOLESCENCE WITH JUVENILE IDIOPATHIC ARTHRITIS TREATED WITH METHOTREXATE. EUREKA: Health Sciences 2020; 4: 70 doi: 10.21303/2504-5679.2020.001372
|
| 2 |
Agazi Gebreselassie, Farshad Aduli, Charles D. Howell. Rheumatologic Diseases and the Liver. Clinics in Liver Disease 2019; 23(2): 247 doi: 10.1016/j.cld.2018.12.007
|
| 3 |
Zulfqarul Haq, Syed Mudasir Ahmad, Ishrat Bashir, Mashooq Ahmad Dar, Afnan Saleem, Azmat Alam Khan, Mohammad Iqbal Yatoo, Shabir Mir, Ankur Rastogi, Mohd Isfaqul Hussain, Riaz A. Shah, Basharat Bhat. Pathogenesis-Related Gene Expression in Response to Trachyspermum ammi Supplementation Along With Probiotics in Chicken Salmonellosis and Insights in Drug Therapeutics. Frontiers in Veterinary Science 2022; 9 doi: 10.3389/fvets.2022.866614
|
| 4 |
Simon DS Fraser, Sharon X Lin, Matthew Stammers, David Culliford, Kinda Ibrahim, Ravina Barrett, Clare Howard, Ruth Johnson, Nicola Barnes, James Batchelor, Christopher Holroyd, Jo Adams, Adam Rischin, Paul Roderick, Paul Rutter, Christopher J Edwards. Persistently normal blood tests in patients taking methotrexate for RA or azathioprine for IBD: a retrospective cohort study. British Journal of General Practice 2022; 72(720): e528 doi: 10.3399/BJGP.2021.0595
|
| 5 |
Chrong-Reen Wang, Hung-Wen Tsai. Autoimmune liver diseases in systemic rheumatic diseases. World Journal of Gastroenterology 2022; 28(23): 2527-2545 doi: 10.3748/wjg.v28.i23.2527
|
| 6 |
Yosra Bedoui, Xavier Guillot, Jimmy Sélambarom, Pascale Guiraud, Claude Giry, Marie Christine Jaffar-Bandjee, Stéphane Ralandison, Philippe Gasque. Methotrexate an Old Drug with New Tricks. International Journal of Molecular Sciences 2019; 20(20): 5023 doi: 10.3390/ijms20205023
|
| 7 |
Saumya Panda. Rational use of laboratory tests in dermatology. Indian Journal of Dermatology, Venereology and Leprology 2018; 84(4): 377 doi: 10.4103/ijdvl.IJDVL_450_18
|
| 8 |
Binit Vaidya, Manisha Bhochhibhoya, Shweta Nakarmi. Efficacy of Vitamin E in Methotrexate-Induced Hepatotoxicity in Rheumatoid Arthritis: An Open-Label Case-Control Study. International Journal of Rheumatology 2020; 2020: 1 doi: 10.1155/2020/5723485
|
| 9 |
Sudarsanan Drishya, Suresh Sulekha Dhanisha, Chandrasekharan Guruvayoorappan.
Antioxidant‐rich fraction of
Amomum subulatum
fruits mitigates experimental methotrexate‐induced oxidative stress by regulating TNF‐α, IL‐1β, and IL‐6 proinflammatory cytokines
. Journal of Food Biochemistry 2022; 46(4) doi: 10.1111/jfbc.13855
|
| 10 |
Andrea Picchianti-Diamanti, Alessandra Aiello, Chiara De Lorenzo, Giovanni Battista Migliori, Delia Goletti. Management of tuberculosis risk, screening and preventive therapy in patients with chronic autoimmune arthritis undergoing biotechnological and targeted immunosuppressive agents. Frontiers in Immunology 2025; 16 doi: 10.3389/fimmu.2025.1494283
|
| 11 |
Mark T. Friedman, Kamille A. West, Peyman Bizargity, Kyle Annen, H. Deniz Gur, Timothy Hilbert. Immunohematology, Transfusion Medicine, Hemostasis, and Cellular Therapy. 2023; : 605 doi: 10.1007/978-3-031-14638-1_81
|
| 12 |
Reyhane Hoshyar, Ahmadreza Sebzari, Mohadeseh Balforoush, Masoomeh Valavi, Mehran Hosseini. The impact of Crocus sativus stigma against methotrexate-induced liver toxicity in rats. Journal of Complementary and Integrative Medicine 2020; 17(2) doi: 10.1515/jcim-2019-0201
|
| 13 |
Narendra Verma, Luce Perie, Carmen Corciulo, Philipp Leucht, Bhama Ramkhelawon, Bruce N. Cronstein, Elisabetta Mueller. Browning of adipose tissue and increased thermogenesis induced by Methotrexate. FASEB BioAdvances 2021; 3(11): 877 doi: 10.1096/fba.2021-00058
|
| 14 |
Krishnendu Manna, Zareen S Khan, Moumita Saha, Snehasis Mishra, Nilesh Gaikwad, Jatindra Nath Bhakta, Kaushik Banerjee, Krishna Das Saha. Manjari Medika Grape Seed Extract Protects Methotrexate-Induced Hepatic Inflammation: Involvement of NF-κB/NLRP3 and Nrf2/HO-1 Signaling System. Journal of Inflammation Research 2023; : 467 doi: 10.2147/JIR.S338888
|
| 15 |
Andrew A. Fanous, Michael Y. Wang, Allan D. Levi. Spine and Spinal Cord Tumors. 2025; doi: 10.1055/b-0045-210216
|
| 16 |
Jordina Llaó, Helena Masnou, Cristina Romero, Anna Bargalló, Cristina Gely, Míriam Mañosa, Jordi Gordillo, Esther Garcia-Planella, Eugeni Domènech. Noninvasive assessment of liver fibrosis in Crohn’s disease patients exposed to methotrexate. European Journal of Gastroenterology & Hepatology 2021; 33(6): 794 doi: 10.1097/MEG.0000000000001799
|
| 17 |
Faisal Akhmal Muslikh, Puja Adi Priatna, Wiwied Ekasari. Pharmacological Effects of Glycyrrhiza glabra L. as Antihepatitis and Hepatoprotective for Children. JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA 2023; 10(1): 126 doi: 10.20473/jfiki.v10i12023.126-140
|
| 18 |
Xia He, Pingli Yao, Mengting Li, Hong Liang, Yilong Liu, Shan Du, Min Zhang, Wenzhuo Sun, Zeyuan Wang, Xin Hao, Ze Yu, Fei Gao, Xinxia Liu, Rongsheng Tong. A Risk Scoring Model for High-Dose Methotrexate-Induced Liver Injury in Children With Acute Lymphoblastic Leukemia Based on Gene Polymorphism Study. Frontiers in Pharmacology 2021; 12 doi: 10.3389/fphar.2021.726229
|
| 19 |
Mohamed A. Morsy, Rania Abdel-Latif, Sara Mohamed Naguib Abdel Hafez, Mahmoud Kandeel, Seham A. Abdel-Gaber. Paeonol Protects against Methotrexate Hepatotoxicity by Repressing Oxidative Stress, Inflammation, and Apoptosis—The Role of Drug Efflux Transporters. Pharmaceuticals 2022; 15(10): 1296 doi: 10.3390/ph15101296
|
| 20 |
Fan Cao, Ming-Han Cheng, Li-Qin Hu, Hui-Hui Shen, Jin-Hui Tao, Xiao-Mei Li, Hai-Feng Pan, Jian Gao. Natural products action on pathogenic cues in autoimmunity: Efficacy in systemic lupus erythematosus and rheumatoid arthritis as compared to classical treatments. Pharmacological Research 2020; 160: 105054 doi: 10.1016/j.phrs.2020.105054
|
| 21 |
Chiaki Inoue, Takehito Yamamoto, Hiroshi Miyata, Hiroshi Suzuki, Tappei Takada. Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation. Journal of Pharmaceutical Health Care and Sciences 2023; 9(1) doi: 10.1186/s40780-023-00306-w
|
| 22 |
Iryna Klymas, Liudmyla Khimion. Aminotransferases activity on additional therapy in rheumatoid arthritis patients with liver disease.. Journal of Clinical Medicine of Kazakhstan 2024; 21(2): 89 doi: 10.23950/jcmk/14398
|
| 23 |
Karthik K Karunakar, Binoy Varghese Cheriyan, Dheena Babu, Devan P, Nandhini J, Suresh Kannan M, Lincy Yabase, Kunal Kataria. Selenium, silver, and gold nanoparticles: Emerging strategies for hepatic oxidative stress and inflammation reduction. Nano TransMed 2025; 4: 100085 doi: 10.1016/j.ntm.2025.100085
|
| 24 |
Graziela S. Gomes, Luiza A. Frank, Renata V. Contri, Maria S. Longhi, Adriana R. Pohlmann, Silvia S. Guterres. Nanotechnology-based alternatives for the topical delivery of immunosuppressive agents in psoriasis. International Journal of Pharmaceutics 2023; 631: 122535 doi: 10.1016/j.ijpharm.2022.122535
|
| 25 |
Nada M. El-Sayed, Esther T. Menze, Mariane G. Tadros, Diana M.F. Hanna. Mangiferin mitigates methotrexate-induced liver injury and suppresses hepatic stellate cells activation in rats: Imperative role of Nrf2/NF-κB/NLRP3 signaling axis. Journal of Ethnopharmacology 2025; 340: 119296 doi: 10.1016/j.jep.2024.119296
|
| 26 |
Elliot M. Frohman, Nicole R. Villemarette-Pittman, Roberto Alejandro Cruz, Reid Longmuir, Vernon Rowe, Elizabeth S. Rowe, Thomas C. Varkey, Lawrence Steinman, Scott S. Zamvil, Teresa C. Frohman. Part II. high-dose methotrexate with leucovorin rescue for severe COVID-19: An immune stabilization strategy for SARS-CoV-2 induced ‘PANIC’ attack. Journal of the Neurological Sciences 2020; 415: 116935 doi: 10.1016/j.jns.2020.116935
|
| 27 |
Nicoletta Nandi, Elena F. Verdu, Detlef Schuppan, Andres Jose Gomez‐Aldana, Maria Ines Pinto‐Sanchez, Francesco Simone Conforti, Marco Maggioni, Flavio Caprioli, Luca Elli. Liver Involvement in Celiac Disease and Immune‐Mediated Diseases of the Small Bowel. Liver International 2025; 45(8) doi: 10.1111/liv.70206
|
| 28 |
Meltem Özgöçmen, Halil Aşcı, Hatice Kübra Doğan, İlter İlhan, Şakir Pekgöz, Ali Mustafaoğlu. A study on Wistar Albino rats: investigating protective role of ramelteon on liver damage caused by methotrexate. Drug and Chemical Toxicology 2022; 45(6): 2678 doi: 10.1080/01480545.2021.1982623
|
| 29 |
Joy C Zhang, Matthew J Stotts, Bethany Horton, David Schiff. Hepatotoxicity from high-dose methotrexate in primary central nervous system lymphoma. Neuro-Oncology Practice 2023; 10(3): 291 doi: 10.1093/nop/npad008
|
| 30 |
Sümeyra Özdemir Çiçek, Zehra Filiz Karaman, Nihal Şahin, Ayşenur Paç Kısaarslan, Muammer Hakan Poyrazoğlu, Ruhan Düşünsel. Evaluation of liver elasticity with shear‐wave elastography in juvenile idiopathic arthritis patients receiving methotrexate. Pediatrics International 2022; 64(1) doi: 10.1111/ped.15239
|
| 31 |
Mustafa Ahmet Afacan, İsmail Tayfur, Burcu Genç Yavuz, Özlem Tataroğlu. Pericardial Tamponade Due to Methotrexate Toxicity: A Case Report. Global Emergency and Critical Care 2023; 2(1): 24 doi: 10.4274/globecc.galenos.2022.76486
|
| 32 |
Riyadh Almalki. The Protective Effect of Roflumilast Against Acute Hepatotoxicity Caused by Methotrexate in Wistar Rats: In vivo Evaluation. Drug Design, Development and Therapy 2024; : 453 doi: 10.2147/DDDT.S438703
|
| 33 |
Ayan Pradhan, Shilpa Sengupta, Ritika Sengupta, Mitali Chatterjee. Attenuation of methotrexate induced hepatotoxicity by epigallocatechin 3-gallate. Drug and Chemical Toxicology 2023; 46(4): 717 doi: 10.1080/01480545.2022.2085738
|
| 34 |
Nieves Leonardo, Susan Lester, Michelle Graham, Claire Barrett, Samuel Whittle, Debra Rowett, Rachelle Buchbinder, Catherine L. Hill. Selection and perception of methotrexate treatment information in people with rheumatoid arthritis. International Journal of Rheumatic Diseases 2020; 23(6): 805 doi: 10.1111/1756-185X.13833
|
| 35 |
Damayanti Damayanti, Karina Dyahtantri Pratiwi, Wisnu Triadi Nugroho. Profile of Psoriasis Vulgaris Patients Treated with Methotrexate at Dr. Soetomo Hospital, Surabaya, 2017–2018. Jurnal Berkala Epidemiologi 2021; 9(1): 70 doi: 10.20473/jbe.V9I12021.70-78
|
| 36 |
AA Dar, A Fehaid, S Alkhatani, S Alarifi, WS Alqahtani, G Albasher, R Almeer, S Alfarraj, AE Abdel Moneim. The protective role of luteolin against the methotrexate-induced hepato-renal toxicity via its antioxidative, anti-inflammatory, and anti-apoptotic effects in rats. Human & Experimental Toxicology 2021; 40(7): 1194 doi: 10.1177/0960327121991905
|
| 37 |
Shabina Khan, Mohammad Ibrahim. A systematic review on hepatoprotective potential of grape and polyphenolic compounds: molecular mechanism and future prospective. Natural Resources for Human Health 2022; 3(2): 196 doi: 10.53365/nrfhh/156261
|
| 38 |
Anwita Sinha, Shekhar Neema, Manish Manrai, Biju Vasudevan, S. Radhakrishnan. Drug-Induced Liver Injury. Indian Journal of Drugs in Dermatology 2021; 7(2): 106 doi: 10.4103/ijdd.ijdd_53_20
|
| 39 |
Derya GÜÇLÜ, Ebru KARAGÜN, Elif Nisa UNLU, Mehtap OKTAY, Özge PASİN. Assessment of the Effect of Psoriasis and Methotrexate Treatment on Liver Stiffness by ARFI Imaging. Konuralp Tıp Dergisi 2023; 15(2): 243 doi: 10.18521/ktd.1280187
|
| 40 |
Omnia E. Hussein, Walaa G. Hozayen, May N. Bin-Jumah, Mousa O. Germoush, Sanaa M. Abd El-Twab, Ayman M. Mahmoud. Chicoric acid prevents methotrexate hepatotoxicity via attenuation of oxidative stress and inflammation and up-regulation of PPARγ and Nrf2/HO-1 signaling. Environmental Science and Pollution Research 2020; 27(17): 20725 doi: 10.1007/s11356-020-08557-y
|
| 41 |
Manisha Parthasarathy, Sabina Evan Prince. Andrographis paniculata (Burm.f.) Nees Alleviates Methotrexate-Induced Hepatotoxicity in Wistar Albino Rats. Life 2023; 13(5): 1173 doi: 10.3390/life13051173
|
| 42 |
Aya M. Abosrea, Heba S. Aboul Ezz, Sahar M. Mahmoud, Mohamed R. Mousa, Nawal A. Ahmed. The potential role of pumpkin seeds oil on methotrexate-induced lung toxicity. Scientific Reports 2023; 13(1) doi: 10.1038/s41598-023-34143-6
|
| 43 |
Angélica María Téllez Arévalo, Abraham Quaye, Luis Carlos Rojas-Rodríguez, Brian D. Poole, Daniela Baracaldo-Santamaría, Claudia M. Tellez Freitas. Synthetic Pharmacotherapy for Systemic Lupus Erythematosus: Potential Mechanisms of Action, Efficacy, and Safety. Medicina 2022; 59(1): 56 doi: 10.3390/medicina59010056
|
| 44 |
Suresh Dhanisha, Sudarsanan Drishya, Rary Mony, Chandrasekharan Guruvayoorappan. Polyphenolic‑rich fraction of Pithecellobium dulce attenuates methotrexate‑induced oxidative stress and associated tissue injury by regulating the TNF‑α, IL‑1β and IL‑6 pro‑inflammatory cytokines. International Journal of Functional Nutrition 2021; 2(3) doi: 10.3892/ijfn.2021.17
|
| 45 |
Natalia Lohvinenko, Volodymyr Shvets, Oleksii Antypenko, Oleksii Voskoboinik, Andrii Bozhkov, Hanna Maslak, Valentyn Oksenych, Oleksandr Kamyshnyi, Sergiy Okovytyy, Serhii Kovalenko. The Application of S-Substituted Pteridine for CCl4-Induced Acute Hepatitis Treatment in Rats. Biomedicines 2025; 13(6): 1276 doi: 10.3390/biomedicines13061276
|
| 46 |
Fadi Kharouf, Pankti Mehta, Virginia Carrizo Abarza, Shangyi Gao, Daniel Pereira, Dafna D Gladman, Denis Poddubnyy, Vinod Chandran. The lack of association between cumulative MTX dose and liver fibrosis in PsA: a cohort study. Rheumatology 2025; doi: 10.1093/rheumatology/keaf282
|
| 47 |
Jeffrey P. Callen, Carol L. Kulp-Shorten. Comprehensive Dermatologic Drug Therapy. 2021; : 156 doi: 10.1016/B978-0-323-61211-1.00014-0
|
| 48 |
茂萍 刘. Research Progress of Liver Involvement in Patients with Systemic Lupus Erythematosus. Advances in Clinical Medicine 2024; 14(01): 1228 doi: 10.12677/ACM.2024.141178
|
| 49 |
Elliot M. Frohman, Nicole R. Villemarette-Pittman, Adriana Rodriguez, Robert Glanzman, Sarah Rugheimer, Oleg Komogortsev, Scott S. Zamvil, Roberto Alejandro Cruz, Thomas C. Varkey, Ashley N. Frohman, Audrey R. Frohman, Matthew S. Parsons, Emily Heckmann Konkle, Teresa C. Frohman. Application of an evidence-based, out-patient treatment strategy for COVID-19: Multidisciplinary medical practice principles to prevent severe disease. Journal of the Neurological Sciences 2021; 426: 117463 doi: 10.1016/j.jns.2021.117463
|
| 50 |
Ismail Aydin, Zuleyha Erisgin, Esma Cinar, M. Zuhal Barak, Yavuz Tekelioglu, Murat Usta, Hasan Serdar Mutlu, Ismail Turkoglu. Should combined MTX and CoQ10 use be reconsidered in terms of steatosis? A biochemical, flow cytometry, histopathological experimental study. Drug and Chemical Toxicology 2024; : 1 doi: 10.1080/01480545.2024.2442660
|
| 51 |
C. Brock, S. E. Rasmussen, A. M. Drewes, H. J. Møller, B. Brock, B. Deleuran, A. D. Farmer, M. Pfeiffer-Jensen, Rômulo Dias Novaes. Vagal Nerve Stimulation-Modulation of the Anti-Inflammatory Response and Clinical Outcome in Psoriatic Arthritis or Ankylosing Spondylitis. Mediators of Inflammation 2021; 2021: 1 doi: 10.1155/2021/9933532
|
| 52 |
Smitha S. Bhat, M. Thanmaya, Sushma Jahagirdar, C.R. Akshatha, Shashanka K. Prasad, R. Sindhu. Biochemical and Molecular Pharmacology in Drug Discovery. 2024; : 427 doi: 10.1016/B978-0-443-16013-4.00020-8
|
| 53 |
Mohamed Abdelrhman Eltahir, Kawthar Abdelgaleil Mohammedsalih, Elhaj Noureldien Mohamed, Faisal Makki Babekir, Amar Mohamed Ismail. Association between Inflammatory Cytokines and Liver Functions in Rheumatoid Arthritis Patients. Sudan Journal of Medical Sciences 2021; 16(2): 276 doi: 10.18502/sjms.v16i2.9294
|
| 54 |
Kanishk Aggarwal, Bhupinder Singh, Abhishek Goel, Durgesh Kumar Agrawal, Sourav Bansal, Sai Gautham Kanagala, Fnu Anamika, Aachal Gupta, Rohit Jain. Complex dichotomous links of nonalcoholic fatty liver disease and inflammatory bowel disease: exploring risks, mechanisms, and management modalities. Intestinal Research 2024; 22(4): 414 doi: 10.5217/ir.2024.00001
|
| 55 |
Abeer Khalid Al-Ghumlas, Manan A. Alhakbany, Aida A. Korish. Antiapoptotic and anticoagulant effects of camel milk and camel urine in methotrexate-induced hepatotoxicity. CyTA - Journal of Food 2023; 21(1): 357 doi: 10.1080/19476337.2023.2202709
|
| 56 |
Christina Kenny, Shawn Chavrimootoo, Anushree Priyadarshini. Cost of treating rheumatoid arthritis in the primary care public health system in Ireland: A time-driven activity-based cost analysis. Exploratory Research in Clinical and Social Pharmacy 2024; 14: 100439 doi: 10.1016/j.rcsop.2024.100439
|
| 57 |
Fatemeh Jamali, Farzaneh Jafary, Mohammad Hossein Aarabi, Farjam Goudarzi, Bahareh Koohshekan, Adel Mohammadalipour. Exploring the oxidative mechanism of methotrexate on catalase enzyme: an in vitro study. Free Radical Research 2025; 59(4): 289 doi: 10.1080/10715762.2025.2481517
|
| 58 |
Valentina Di Francesco, Martina Di Francesco, Paolo Decuzzi, Roberto Palomba, Miguel Ferreira. Synthesis of Two Methotrexate Prodrugs for Optimizing Drug Loading into Liposomes. Pharmaceutics 2021; 13(3): 332 doi: 10.3390/pharmaceutics13030332
|
| 59 |
Reza Azadnasab, Hadi Kalantar, Layasadat Khorsandi, Heibatullah Kalantari, Mohammad Javad Khodayar. Epicatechin ameliorative effects on methotrexate-induced hepatotoxicity in mice. Human & Experimental Toxicology 2021; 40(12_suppl): S603 doi: 10.1177/09603271211047924
|
| 60 |
Tamir Malley, George Corfield, Phanida Fung, Donna Heneghan, Joanne Kitchen. Transaminitis and neutropenia are rare in patients on methotrexate: evidence from a large cohort of inflammatory arthritis patients. Rheumatology 2019; 58(11): 2061 doi: 10.1093/rheumatology/kez168
|
| 61 |
Husam Shawakh, Rashed Aljundi, Hassan Bdeiwi, Hala Sultan, Zaher Mezketli, Tala Jouma Al-Hejazi, Sally Shehab, Sami Albitar. A rare case of systemic sclerosis accompanied with antibody-negative cholangitis treated with methotrexate: A case report. Medicine: Case Reports and Study Protocols 2025; 6(2): e00360 doi: 10.1097/MD9.0000000000000360
|
| 62 |
M. Gaschignard, T. Lamireau, R. Enaud. Quand évoquer une hépatite médicamenteuse chez l’enfant ?. Perfectionnement en Pédiatrie 2022; 5(1): 39 doi: 10.1016/j.perped.2022.01.003
|
| 63 |
Debbie A. Olsson‐White, John K. Olynyk, Oyekoya T. Ayonrinde, Shereen Paramalingam, Helen I. Keen. Assessment of liver fibrosis markers in people with rheumatoid arthritis on methotrexate. Internal Medicine Journal 2022; 52(4): 566 doi: 10.1111/imj.15125
|
| 64 |
Anamika Dwivedi, Abhimanyu Kumar Jha, Varsha Gupta. Impact of MTHFR C677T and A1298C gene polymorphisms on MTX drug toxicity and efficacy profile of RA patients in North India. Meta Gene 2020; 24: 100705 doi: 10.1016/j.mgene.2020.100705
|
| 65 |
Matthew Brovold, Dale Keller, Shay Soker. Differential fibrotic phenotypes of hepatic stellate cells within 3D liver organoids. Biotechnology and Bioengineering 2020; 117(8): 2516 doi: 10.1002/bit.27379
|
| 66 |
Ahmad Ghorbani, Sara Hooshmand. Protective Effects of <b><i>Morus nigra</i></b> and Its Phytochemicals against Hepatotoxicity: A Review of Preclinical Studies. Pharmacology 2021; 106(5-6): 233 doi: 10.1159/000515032
|
| 67 |
Pratik Karmakar, Tyler J. Finnegan, Darian C. Rostam, Sagarika Taneja, Sefa Uçar, Alexandar L. Hansen, Curtis E. Moore, Christopher M. Hadad, Kornkanya Pratumyot, Jon R. Parquette, Jovica D. Badjić. Molecular bowls for inclusion complexation of toxic anticancer drug methotrexate. Chemical Science 2024; 15(26): 10155 doi: 10.1039/D3SC05627A
|
| 68 |
Stefanie Glaubitz, Rachel Zeng, Goran Rakocevic, Jens Schmidt. Update on Myositis Therapy: From Today’s Standards to Tomorrow’s Possibilities. Current Pharmaceutical Design 2022; 28(11): 863 doi: 10.2174/1381612827666211115165353
|
| 69 |
N. van der Spuy. Athena: Specialty Certificate Examination case for formulation and systemic therapy. Clinical and Experimental Dermatology 2022; 47(7): 1393 doi: 10.1111/ced.14943
|
| 70 |
Vicenç Ruiz de Porras, Mariona Figols, Albert Font, Eva Pardina. Curcumin as a hepatoprotective agent against chemotherapy-induced liver injury. Life Sciences 2023; 332: 122119 doi: 10.1016/j.lfs.2023.122119
|
| 71 |
Behrooz Johari, Mohammad Rahmati, Leila Nasehi, Yousef Mortazavi, Mohammad Hasan Faghfoori, Hamed Rezaeejam. Evaluation of STAT3 decoy oligodeoxynucleotides' synergistic effects on radiation and/or chemotherapy in metastatic breast cancer cell line. Cell Biology International 2020; 44(12): 2499 doi: 10.1002/cbin.11456
|
| 72 |
Peter Nash, Pascal Richette, Laure Gossec, Antonio Marchesoni, Christopher Ritchlin, Koji Kato, Erin L McDearmon-Blondell, Elizabeth Lesser, Reva McCaskill, Dai Feng, Jaclyn K Anderson, Eric M Ruderman. Upadacitinib as monotherapy and in combination with non-biologic disease-modifying antirheumatic drugs for psoriatic arthritis. Rheumatology 2022; 61(8): 3257 doi: 10.1093/rheumatology/keab905
|
| 73 |
Elias Adikwu, Nelson Ebinyo. Potential Therapeutic Activities of Melatonin and Alpha Lipoic Acid on Methotrexate-Induced Hepatotoxicity in Rats. Egyptian Journal of Basic and Clinical Pharmacology 2020; 10 doi: 10.32527/2020/101433
|
| 74 |
Katie Voelz, Gwendolyn Miller, Cathy Lee-Miller. 6-Mercaptopurine-associated Sinusoidal Obstructive Syndrome During Interim Maintenance I: A Case Report. Journal of Pediatric Hematology/Oncology 2024; 46(5): e317 doi: 10.1097/MPH.0000000000002883
|
| 75 |
Ana Carolina de Figueiredo Costa, Luane Macedo de Sousa, Joana Maria dos Santos Alves, Paula Goes, Karuza Maria Alves Pereira, Ana Paula Negreiros Nunes Alves, Mariana Lima Vale, Delane Viana Gondim. Anti-inflammatory and Hepatoprotective Effects of Quercetin in an Experimental Model of Rheumatoid Arthritis. Inflammation 2021; 44(5): 2033 doi: 10.1007/s10753-021-01479-y
|
| 76 |
Anthony M. Kyriakopoulos, Markus Nagl, Ramesh C. Gupta, Janusz Marcinkiewicz. Taurine 12. Advances in Experimental Medicine and Biology 2022; 1370: 99 doi: 10.1007/978-3-030-93337-1_9
|
| 77 |
Anastasiia V. Asoskova, Dmitry А. Sychev, Alexey A. Kubanov. Methotrexate Safety in Psoriasis: An Overview. Annals of the Russian academy of medical sciences 2021; 76(3): 254 doi: 10.15690/vramn1527
|
| 78 |
Erin Boh, Andrew Joselow, Brittany Stumpf. Advances in Psoriasis. 2021; : 103 doi: 10.1007/978-3-030-54859-9_9
|
| 79 |
Noha Adel Yassin, Mai Haroon, Azza Elhamshary. Methotrexate Hepatotoxicity in Children with Juvenile Idiopathic Arthritis: A Single-Center Study. Current Rheumatology Reviews 2021; 17(2): 242 doi: 10.2174/1573397116666201211123142
|
| 80 |
Muhammad Nasir Hayat Malik, Muhammad Nouman Tahir, Tariq G. Alsahli, Md. Mahedi Hassan Tusher, Sami I. Alzarea, Bader Alsuwayt, Shah Jahan, Hesham A. M. Gomaa, Mohamed E. Shaker, Muhammad Ali, Irfan Anjum, Muhammad Tariq Khan, Muhammad Roman, Ramla Shabbir. Geraniol Suppresses Oxidative Stress, Inflammation, and Interstitial Collagenase to Protect against Inflammatory Arthritis. ACS Omega 2023; 8(40): 37128 doi: 10.1021/acsomega.3c04684
|
| 81 |
Biljana Radovanović-Dinić, Snežana Tešić-Rajković, Valentina Zivkovic, Saša Grgov. Clinical connection between rheumatoid arthritis and liver damage. Rheumatology International 2018; 38(5): 715 doi: 10.1007/s00296-018-4021-5
|
| 82 |
Aya I. Abdelaziz, Eman M. Mantawy, Amany M. Gad, Hala M. Fawzy, Samar S. Azab. Activation of pCREB/Nrf-2 signaling mediates re-positioning of liraglutide as hepato-protective for methotrexate -induced liver injury (MILI). Food and Chemical Toxicology 2019; 132: 110719 doi: 10.1016/j.fct.2019.110719
|
| 83 |
Mervat Mohamed, Azza Kamal El Sheikh, Hanaa Hassanien Mohammed. Modulation of Liver P-Glycoprotien Expression May Contribute to Gossypin Protection against Methotrexate-Induced Hepatotoxicity. Indian Journal of Pharmacology 2021; 53(1): 25 doi: 10.4103/ijp.IJP_824_19
|
| 84 |
Lutz Wollin, Dieudonnée Togbe, Bernhard Ryffel, Nicholas Dunne. Effects of Nintedanib in an Animal Model of Liver Fibrosis. BioMed Research International 2020; 2020(1) doi: 10.1155/2020/3867198
|
| 85 |
Michele S. Barnhill, Joshua M. Steinberg, Joseph J. Jennings, James H. Lewis. Hepatotoxicty of Agents Used in the Management of Inflammatory Bowel Disease: a 2020 Update. Current Gastroenterology Reports 2020; 22(9) doi: 10.1007/s11894-020-00781-3
|
| 86 |
Mina M Raahimi, Amy Livesey, Jessica Hamilton, Alexa R Shipman, Richard J Aspinall. Liver fibrosis for the dermatologist: a review. Clinical and Experimental Dermatology 2023; 48(4): 303 doi: 10.1093/ced/llac083
|
| 87 |
Yi‐Huan Wu, Chih‐Yang Cheng, Yen‐Yang Chen, Feng‐Yin Li. Drug design of human dihydrofolate reductase (hDHFR) inhibitors with deep learning. Journal of the Chinese Chemical Society 2023; 70(5): 1258 doi: 10.1002/jccs.202350068
|
| 88 |
Esam M. Aboubakr, Ahmed R. N. Ibrahim, Fares E. M. Ali, Ahmed A. E. Mourad, Adel M. Ahmad, Amal Hofni. Fasudil Ameliorates Methotrexate-Induced Hepatotoxicity by Modulation of Redox-Sensitive Signals. Pharmaceuticals 2022; 15(11): 1436 doi: 10.3390/ph15111436
|
| 89 |
Shalini Mani, Sakshi Tyagi, Km Vaishali Pal, Himanshi Jaiswal, Anvi Jain, Aaru Gulati, Manisha Singh. Free Radical Biology and Environmental Toxicity. Molecular and Integrative Toxicology 2021; : 73 doi: 10.1007/978-3-030-83446-3_4
|
| 90 |
Bita Anvari. Methotrexate Hepatotoxicity in Rheumatoid Arthritis: An Analysis of the Physicians’ Policy. Current Rheumatology Reviews 2020; 16(1): 67 doi: 10.2174/1573397115666190618124407
|
| 91 |
Cengiz Dibekoğlu, Kubilay Kemertaş, Hatice Aygun, Oytun Erbaş. Ivermectin Attenuates Methotrexate-Induced Liver Fibrosis by Reducing TGF-β and Syndecan-1 Expression. Medicina 2025; 61(6): 1036 doi: 10.3390/medicina61061036
|
| 92 |
Muhsina Kakkadath, Disha Naidu, S. K. Kanthlal, Khan Sharun, Raghuram Kandimalla. Combating Methotrexate Resistance in Cancer Treatment: A Review on Navigating Pathways and Enhancing Its Efficacy With Fat‐Soluble Vitamins. Scientifica 2025; 2025(1) doi: 10.1155/sci5/8259470
|
| 93 |
Jiayi Wang, Jun Yin, Wei Li, Chunyuan Xiao, Jie Han, Fanfan Zhou. Association between SLCO1A2 genetic variation and methotrexate toxicity in human rheumatoid arthritis treatment. Journal of Biochemical and Molecular Toxicology 2020; 34(8) doi: 10.1002/jbt.22513
|
| 94 |
Suresh S. Dhanisha, Sudarsanan Drishya, Karyath P. Gangaraj , Muliyar K. Rajesh, Chandrasekharan Guruvayoorappan. Molecular Docking Studies of Naringenin and its Protective Efficacy against
Methotrexate Induced Oxidative Tissue Injury. Anti-Cancer Agents in Medicinal Chemistry 2021; 22(1): 169 doi: 10.2174/1871520621666210322102915
|
| 95 |
Steven Dudics, David Langan, Rakeshchandra R. Meka, Shivaprasad H. Venkatesha, Brian M. Berman, Chun-Tao Che, Kamal D. Moudgil. Natural Products for the Treatment of Autoimmune Arthritis: Their Mechanisms of Action, Targeted Delivery, and Interplay with the Host Microbiome. International Journal of Molecular Sciences 2018; 19(9): 2508 doi: 10.3390/ijms19092508
|
| 96 |
S. E. Meshkani, D. Mahdian, K. Abbaszadeh-Goudarzi, M. Abroudi, G. Dadashizadeh, J.-D. Lalau, M. E. De Broe, H. Hosseinzadeh. Metformin as a protective agent against natural or chemical toxicities: a comprehensive review on drug repositioning. Journal of Endocrinological Investigation 2020; 43(1): 1 doi: 10.1007/s40618-019-01060-3
|
| 97 |
Lobna Abdel Salam, Amal Q. Aldarwesh, Hatem H. Eleishi. Whole exome sequencing (WES) of methotrexate response/adverse event profile in rheumatoid arthritis patients. The Egyptian Rheumatologist 2021; 43(4): 287 doi: 10.1016/j.ejr.2020.08.006
|
| 98 |
Yuzhu Cao, Hang Shi, Zhiguang Sun, Jiawei Wu, Yawen Xia, Yufei Wang, Yuanyuan Wu, Xiaoman Li, Wenxing Chen, Aiyun Wang, Yin Lu. Protective Effects of Magnesium Glycyrrhizinate on Methotrexate-Induced Hepatotoxicity and Intestinal Toxicity May Be by Reducing COX-2. Frontiers in Pharmacology 2019; 10 doi: 10.3389/fphar.2019.00119
|
| 99 |
Volodymyr V. Oberemok, Oksana Andreeva, Kateryna Laikova, Edie Alieva, Zenure Temirova. Rheumatoid Arthritis Has Won the Battle but Not the War: How Many Joints Will We Save Tomorrow?. Medicina 2023; 59(10): 1853 doi: 10.3390/medicina59101853
|
| 100 |
Tong Zhu, Selina Moy, Udaya Valluri, Ying Cao, Wenhui Zhang, Taiji Sawamoto, Vishala Chindalore, Bola Akinlade. Investigation of Potential Drug–Drug Interactions between Peficitinib (ASP015K) and Methotrexate in Patients with Rheumatoid Arthritis. Clinical Drug Investigation 2020; 40(9): 827 doi: 10.1007/s40261-020-00937-z
|
| 101 |
Fernando Magro, Gonçalo Cordeiro, Andreia Martins Dias, Maria Manuela Estevinho. Inflammatory Bowel Disease – Non-biological treatment. Pharmacological Research 2020; 160: 105075 doi: 10.1016/j.phrs.2020.105075
|
| 102 |
Tugba Ozkok Akbulut, Filiz Topaloglu Demir, Ilteris Oguz Topal, Asude Kara Polat, Ayse Serap Karadag, Melek Aslan Kayiran, Ezgi Ozkur, Ilknur Kıvanc Altunay. Drug survival and predictor factors for discontinuation of methotrexate in psoriasis: a real‐life multicenter study. International Journal of Dermatology 2021; 60(9): 1140 doi: 10.1111/ijd.15628
|
| 103 |
Yoshiya Tanaka, Tsuneyo Mimori, Hisashi Yamanaka, Naomi Sunaga, Kazuo Morita, Junko Kimura, Tsutomu Takeuchi. Effectiveness, safety, and methotrexate dose-tapering pattern over two years of treatment with adalimumab and ≥12 mg/week methotrexate for early rheumatoid arthritis: Results of the HAWK postmarketing surveillance study in Japan. Modern Rheumatology 2020; 30(3): 424 doi: 10.1080/14397595.2019.1639931
|
| 104 |
Manjusha Sajith, Atmaram Pawar, Vibha Bafna, Sandip Bartakke. High-dose methotrexate-induced fulminant hepatic failure and pancytopenia in an acute lymphoblastic leukaemia paediatric patient. European Journal of Hospital Pharmacy 2020; 27(3): 178 doi: 10.1136/ejhpharm-2019-001944
|
| 105 |
Dalia E. Ali, Sherouk Hussein Sweilam, Ahmed M. Atwa, Ali M. Elgindy, Aya M. Mustafa, Manar M. Esmail, Mahmoud Abdelrahman Alkabbani, Mohamed Magdy Senna, Riham A. El-Shiekh. HPLC-HRMS/MS and anti-inflammatory effects of bunya pine resin through multifaceted pathway modulation: NUMB/NOTCH1/HES1/mTOR/ PI3K/HMGB1 signaling cascades. Inflammopharmacology 2025; doi: 10.1007/s10787-025-01660-x
|
| 106 |
Sumera Qasim, Yusra Habib Khan, Ambreen Malik Uttra, Nasser Hadal Alotaibi, Abdullah Salah Alanazi, Abdulaziz I. Alzarea, Ahmed D. Alatawi, Tauqeer Hussain Mallhi. Appraisal of anti-inflammatory and immunomodulatory potential of ramipril against Freund’s adjuvant-provoked arthritic rat model. Inflammopharmacology 2023; 31(6): 3115 doi: 10.1007/s10787-023-01306-w
|
| 107 |
AA Fouad, HM Hafez, AAH Hamouda. Hydrogen sulfide modulates IL-6/STAT3 pathway and inhibits oxidative stress, inflammation, and apoptosis in rat model of methotrexate hepatotoxicity. Human & Experimental Toxicology 2020; 39(1): 77 doi: 10.1177/0960327119877437
|
| 108 |
Jason Wee, Salar Sobhi, Bastiaan De Boer, Dan Xu. Liver rheumatoid nodules imitating liver malignancy: a rare occurrence. BMJ Case Reports 2020; 13(12): e234366 doi: 10.1136/bcr-2020-234366
|
| 109 |
Nevertyty Mohamed Mahmoud, Shimaa M. Elshazly, Fatma El-shaarawy, Sawsan A. Zaitone, Afaf A. Aldahish, Gehan A. Ahmed, Manal S. Fawzy, Sheka Yagub Aloyouni, Sally Y. Abed, Tahani Saeedi, Shaimaa S. El-Sayed. Nitazoxanide mitigates methotrexate hepatotoxicity in rats: role in inhibiting apoptosis and regulating endoplasmic reticulum stress. Frontiers in Pharmacology 2024; 15 doi: 10.3389/fphar.2024.1491249
|
| 110 |
Juman Alsaab, Wedad S. Sarawi, Ahlam M. Alhusaini, Iman H. Hasan, Sumayya Alturaif, Rehab A. Ali, Nouf M. Alrasheed, Raeesa Mohammad, Norah K. Algarzae. Procyanidin B2 mitigates methotrexate-induced hepatic pyroptosis by suppressing TLR4/NF-κB and caspase-3/GSDME pathways. Food and Chemical Toxicology 2025; 199: 115341 doi: 10.1016/j.fct.2025.115341
|
| 111 |
A. P. Pereverzev, O. D. Ostroumova. Drug-Induced Fatty Liver Disease. Safety and Risk of Pharmacotherapy 2020; 8(2): 66 doi: 10.30895/2312-7821-2020-8-2-66-76
|
| 112 |
Zhiwei Miao, Mingjia Gu, Jing Yan, Lidan Lu, Yan Xu, Liqin Ning, Yi Xu. Dual-targeted colon-based integrated micelle drug delivery system for treatment of ulcerative colitis. Journal of Drug Targeting 2022; 30(6): 657 doi: 10.1080/1061186X.2022.2052887
|
| 113 |
Leon G. D’Cruz, Kevin G. McEleney, Kyle B. C. Tan, Priyank Shukla, Philip V. Gardiner, Patricia Connolly, Caroline Conway, Diego Cobice, David S. Gibson. Clinical and Laboratory Associations with Methotrexate Metabolism Gene Polymorphisms in Rheumatoid Arthritis. Journal of Personalized Medicine 2020; 10(4): 149 doi: 10.3390/jpm10040149
|
| 114 |
Ena Pavelic, Vladimir Blagaic, Paulo Zekan, Petra Glad Stritof, Mara Bebek, Josko Bilandzic, Milan Pavlovic, Mihovil Herceg, Melanie Deutsch. Occurrence of Liver Damage and Obstetric Outcomes in Pregnant Women Diagnosed with Pruritus during Pregnancy: A Retrospective Study. International Journal of Clinical Practice 2022; 2022: 1 doi: 10.1155/2022/5913712
|
| 115 |
Marcia Shade, Kyle Rector, Kevin Kupzyk. Voice Assistant Reminders and the Latency of Scheduled Medication Use in Older Adults With Pain: Descriptive Feasibility Study. JMIR Formative Research 2021; 5(9): e26361 doi: 10.2196/26361
|
| 116 |
Snehanjana Patra, Tania Pal Choudhury, Sanchari Barman. The Journey of Methotrexate and Potential Alternative Pharmacotherapies for Rheumatoid Arthritis. Current Drug Research Reviews 2025; 17(2): 142 doi: 10.2174/0125899775258634231226052204
|
| 117 |
Giovanni Damiani, Paolo Amerio, Federico Bardazzi, Carlo G. Carrera, Andrea Conti, Francesco Cusano, Paolo Dapavo, Clara DeSimone, May El Hachem, Gabriella Fabbrocini, Paolo Gisondi, Francesco Loconsole, Giuseppe Micali, Iria Neri, Aurora Parodi, Stefano Piaserico, Marco Romanelli, Luca Stingeni, Paolo D. M. Pigatto. Real-World Experience of Methotrexate in the Treatment of Skin Diseases: an Italian Delphi Consensus. Dermatology and Therapy 2023; 13(6): 1219 doi: 10.1007/s13555-023-00930-2
|