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Cited by in CrossRef
For: Sun XZ, Zhao DY, Zhou YC, Wang QQ, Qin G, Yao SK. Alteration of fecal tryptophan metabolism correlates with shifted microbiota and may be involved in pathogenesis of colorectal cancer. World J Gastroenterol 2020; 26(45): 7173-7190 [PMID: 33362375 DOI: 10.3748/wjg.v26.i45.7173]
URL: https://www.wjgnet.com/1007-9327/full/v26/i45/7173.htm
Number Citing Articles
1
Sushma S. Kumar, Ashna Fathima, Preeti Srihari, Trinath Jamma. Host-gut microbiota derived secondary metabolite mediated regulation of Wnt/β-catenin pathway: a potential therapeutic axis in IBD and CRCFrontiers in Oncology 2024; 14 doi: 10.3389/fonc.2024.1392565
2
Lujia Zhou, Zhengting Jiang, Zhilin Zhang, Juan Xing, Daorong Wang, Dong Tang. Progress of gut microbiome and its metabolomics in early screening of colorectal cancerClinical and Translational Oncology 2023; 25(7): 1949 doi: 10.1007/s12094-023-03097-6
3
Akeem Santos, Zeneng Wang, Rashmi Bharti, Goutam Dey, Naseer Sangwan, William Baldwin, Ajay Zalavadia, Alex Myers, Olivia G. Huffman, Justin D. Lathia, Stanley L. Hazen, Ofer Reizes, Mohammed Dwidar. Leveraging dysregulated tumor metabolism for targeting anticancer bacteriaScience Advances 2025; 11(24) doi: 10.1126/sciadv.ads1630
4
Elsa L.S.A. van Liere, Laura J. van Dijk, Sofie Bosch, Louis Vermeulen, Martijn W. Heymans, George L. Burchell, Tim G.J. de Meij, Dewkoemar Ramsoekh, Nanne K.H. de Boer. Urinary volatile organic compounds for colorectal cancer screening: A systematic review and meta-analysisEuropean Journal of Cancer 2023; 186: 69 doi: 10.1016/j.ejca.2023.03.002
5
Advances in Host Genetics and Microbiome in Colorectal Cancer-Related PhenotypesAdvances in Genetics 2024; 112: 367 doi: 10.1016/bs.adgen.2024.08.002
6
Xingzhao Chen, Zhiyuan Ma, Zhiqiang Yi, Enqin Wu, Zhengye Shang, Biguang Tuo, Taolang Li, Xuemei Liu. The effects of metabolism on the immune microenvironment in colorectal cancerCell Death Discovery 2024; 10(1) doi: 10.1038/s41420-024-01865-z
7
Samuel Oluwadare Olalekan, Olalekan Olanrewaju Bakare, Ifabunmi Oduyemi Osonuga, Abayomi Samson Faponle, Bukunola Oluyemisi Adegbesan, Esther Nkechi Ezima. Gut microbiota-derived metabolites: implications for metabolic syndrome and therapeutic interventionsThe Egyptian Journal of Internal Medicine 2024; 36(1) doi: 10.1186/s43162-024-00342-4
8
Hongbo Zhang, Yanhui Yu, Jianhua Li, Pengtao Gong, Xiaocen Wang, Xin Li, Yidan Cheng, Xiuyan Yu, Nan Zhang, Xichen Zhang. Changes of gut microbiota in colorectal cancer patients with Pentatrichomonas hominis infectionFrontiers in Cellular and Infection Microbiology 2022; 12 doi: 10.3389/fcimb.2022.961974
9
Maira Jimenez-Sanchez, Larissa S. Celiberto, Hyungjun Yang, Ho Pan Sham, Bruce A. Vallance. The gut-skin axis: a bi-directional, microbiota-driven relationship with therapeutic potentialGut Microbes 2025; 17(1) doi: 10.1080/19490976.2025.2473524
10
Jiahui Liu, Ruxian Tian, Caiyu Sun, Ying Guo, Lei Dong, Yumei Li, Xicheng Song. Microbial metabolites are involved in tumorigenesis and development by regulating immune responsesFrontiers in Immunology 2023; 14 doi: 10.3389/fimmu.2023.1290414
11
Ziran Kang, Shanshan Jiang, Jing-Yuan Fang, Huimin Chen. Intestinal dysbiosis and colorectal cancerChinese Medical Journal 2025; 138(11): 1266 doi: 10.1097/CM9.0000000000003617
12
Wenyue Cheng, Fan Li, Rongcun Yang. The Roles of Gut Microbiota Metabolites in the Occurrence and Development of Colorectal Cancer: Multiple Insights for Potential Clinical ApplicationsGastro Hep Advances 2024; 3(6): 855 doi: 10.1016/j.gastha.2024.05.012
13
Randa H. Khattab, Rana H. Abo-Hammam, Mohammed Salah, Amro M. Hanora, Sarah Shabayek, Samira Zakeer. Multi-omics analysis of fecal samples in colorectal cancer Egyptians patients: a pilot studyBMC Microbiology 2023; 23(1) doi: 10.1186/s12866-023-02991-x
14
Abdulla A.-B. Badawy. Tryptophan metabolism and disposition in cancer biology and immunotherapyBioscience Reports 2022; 42(11) doi: 10.1042/BSR20221682
15
Wen Chen, Liang Wen, Yingying Bao, Zengwei Tang, Jianhui Zhao, Xiaozhen Zhang, Tao Wei, Jian Zhang, Tao Ma, Qi Zhang, Xiao Zhi, Jin Li, Cheng Zhang, Lei Ni, Muchun Li, Tingbo Liang. Gut flora disequilibrium promotes the initiation of liver cancer by modulating tryptophan metabolism and up-regulating SREBP2Proceedings of the National Academy of Sciences 2022; 119(52) doi: 10.1073/pnas.2203894119
16
Tayah Turocy, Jason M. Crawford. Bacterial small molecule metabolites implicated in gastrointestinal cancer developmentNature Reviews Microbiology 2025; 23(2): 106 doi: 10.1038/s41579-024-01103-4
17
Integrated single cell and bulk RNA sequencing analyses reveal the impact of tryptophan metabolism on prognosis and immunotherapy in colon cancerScientific Reports 2025; 15(1) doi: 10.1038/s41598-025-85893-4
18
Madhur Wyatt, Ankan Choudhury, Gabriella Von Dohlen, Jeffery L. Heileson, Jeffrey S. Forsse, Sumudu Rajakaruna, Manja Zec, Malak M. Tfaily, Leigh Greathouse, Jennifer M. Auchtung, Funmilola Abidemi Ayeni. Randomized control trial of moderate dose vitamin D alters microbiota stability and metabolite networks in healthy adultsMicrobiology Spectrum 2024; 12(10) doi: 10.1128/spectrum.00083-24
19
Janina N. Zünd, Denisa Mujezinovic, Markus Reichlin, Serafina Plüss, Marina Caflisch, Serina Robinson, Christophe Lacroix, Benoit Pugin. Novel cross-feeding human gut microbes metabolizing tryptophan to indole-3-propionateGut Microbes 2025; 17(1) doi: 10.1080/19490976.2025.2501195
20
Shuang Zhang, Pengyue Zhang, Xin Hu. Causal Relationship between Helicobacter pylori Infection and Autoimmune Diseases of the Digestive System: Evidence from a Mendelian Randomization StudyDigestive Diseases 2025; 43(4): 434 doi: 10.1159/000545597
21
Xuewei Ye, Haiyi Li, Komal Anjum, Xinye Zhong, Shuping Miao, Guowan Zheng, Wei Liu, Lanjuan Li. Dual Role of Indoles Derived From Intestinal Microbiota on Human HealthFrontiers in Immunology 2022; 13 doi: 10.3389/fimmu.2022.903526
22
Areej A. Alhhazmi, Renad M. Alhamawi, Reema M. Almisned, Hanouf A. Almutairi, Ahdab A. Jan, Shahad M. Kurdi, Yahya A. Almutawif, Waleed Mohammed-Saeid. Gut Microbial and Associated Metabolite Markers for Colorectal Cancer DiagnosisMicroorganisms 2023; 11(8): 2037 doi: 10.3390/microorganisms11082037
23
Xinhao Du, Qing Li, Zhenzhen Tang, Li Yan, Ling Zhang, Qiao Zheng, Xianghao Zeng, Guimei Chen, Huawen Yue, Jun Li, Ming Zhao, Yuan-Ping Han, Xiangsheng Fu. Alterations of the Gut Microbiome and Fecal Metabolome in Colorectal Cancer: Implication of Intestinal Metabolism for TumorigenesisFrontiers in Physiology 2022; 13 doi: 10.3389/fphys.2022.854545
24
Wei Li, Xiaoyong Zhang, Yue Feng, Haote Han, Jinhong Cai, Huan Zhao, Shouxin Li, Jingkui Tian, Wei Zhu. Deciphering the metabolic profile and anti-colorectal cancer mechanism of Capilliposide A using ultra performance liquid chromatography mass spectrometry combined with non-targeted metabolomics studiesJournal of Pharmaceutical and Biomedical Analysis 2023; 234: 115548 doi: 10.1016/j.jpba.2023.115548
25
Najwa-Joelle Metri, Ali S Butt, Ava Murali, Genevieve Z Steiner-Lim, Chai K Lim. Normative Data on Serum and Plasma Tryptophan and Kynurenine Concentrations from 8089 Individuals Across 120 Studies: A Systematic Review and Meta-AnalysisInternational Journal of Tryptophan Research 2023; 16 doi: 10.1177/11786469231211184
26
Coco Duizer, Marcel R. de Zoete. The Role of Microbiota-Derived Metabolites in Colorectal CancerInternational Journal of Molecular Sciences 2023; 24(9): 8024 doi: 10.3390/ijms24098024
27
Qinhan Cao, Meiju Yang, Min Chen. Metabolic interactions: how gut microbial metabolites influence colorectal cancerFrontiers in Microbiology 2025; 16 doi: 10.3389/fmicb.2025.1611698
28
Huahuan Liu, Zhongbo Bian, Qiuyu Zhang, Zhipeng Xiao, Yu Cao, Xiaodie Sun, Yong Qin, Lianzhi Mao, Xinwei Chu, Wenzhen Liao, Longying Zha, Suxia Sun. Sodium butyrate inhibits colitis-associated colorectal cancer through preventing the gut microbiota dysbiosis and reducing the expression of NLRP3 and IL-1βJournal of Functional Foods 2021; 87: 104862 doi: 10.1016/j.jff.2021.104862
29
Guoyu Dai, Xiang Chen, Yao He. The Gut Microbiota Activates AhR Through the Tryptophan Metabolite Kyn to Mediate Renal Cell Carcinoma MetastasisFrontiers in Nutrition 2021; 8 doi: 10.3389/fnut.2021.712327
30
Minjing Zhu. Role of amino acid metabolism in tumor immune microenvironment of colorectal cancerAmerican Journal of Cancer Research 2025; 15(1): 233 doi: 10.62347/ZSOO2247
31
Tao Tang, Ya Li, Jie Wang, Mauricio A. Elzo, Jiahao Shao, Yanhong Li, Siqi Xia, Huimei Fan, Xianbo Jia, Songjia Lai. Untargeted Metabolomics Reveals Intestinal Pathogenesis and Self-Repair in Rabbits Fed an Antibiotic-Free DietAnimals 2021; 11(6): 1560 doi: 10.3390/ani11061560
32
Yufei Liu, Zhangming Pei, Tong Pan, Hongchao Wang, Wei Chen, Wenwei Lu. Indole metabolites and colorectal cancer: Gut microbial tryptophan metabolism, host gut microbiome biomarkers, and potential intervention mechanismsMicrobiological Research 2023; 272: 127392 doi: 10.1016/j.micres.2023.127392
33
Zhanhui Lu, Chengcheng Zhang, Jia Zhang, Wan Su, Guoying Wang, Zhongqi Wang. The Kynurenine Pathway and Indole Pathway in Tryptophan Metabolism Influence Tumor ProgressionCancer Medicine 2025; 14(6) doi: 10.1002/cam4.70703
34
Bing Han, Yufei Zhai, Xuan Li, Huan Zhao, Chengtao Sun, Yuqing Zeng, Weiping Zhang, Jinjian Lu, Guoyin Kai. Total flavonoids of Tetrastigma hemsleyanum Diels et Gilg inhibits colorectal tumor growth by modulating gut microbiota and metabolitesFood Chemistry 2023; 410: 135361 doi: 10.1016/j.foodchem.2022.135361
35
Dingka Song, Xiuli Wang, Yongjing Ma, Ning-Ning Liu, Hui Wang. Beneficial insights into postbiotics against colorectal cancerFrontiers in Nutrition 2023; 10 doi: 10.3389/fnut.2023.1111872
36
Patrick Niekamp, Chang H. Kim. Microbial Metabolite Dysbiosis and Colorectal CancerGut and Liver 2023; 17(2): 190 doi: 10.5009/gnl220260
37
Masaru Tanaka, Ágnes Szabó, László Vécsei. Redefining Roles: A Paradigm Shift in Tryptophan–Kynurenine Metabolism for Innovative Clinical ApplicationsInternational Journal of Molecular Sciences 2024; 25(23): 12767 doi: 10.3390/ijms252312767
38
Wei Li, Shenghong Guan, Xueli Hu, Huan Zhao, Jinhong Cai, Xiaohan Li, Xiaoyong Zhang, Wei Zhu, Xin Pan, Shouxin Li, Jingkui Tian. Lysimachia capillipes Hemsl. saponins ameliorate colorectal cancer in mice via regulating gut microbiota and restoring metabolic profilesFitoterapia 2024; 175: 105959 doi: 10.1016/j.fitote.2024.105959
39
Tianxiang Yin, Xiang Zhang, Yan Xiong, Bohao Li, Dong Guo, Zhou Sha, Xiaoyuan Lin, Haibo Wu. Exploring gut microbial metabolites as key players in inhibition of cancer progression: Mechanisms and therapeutic implicationsMicrobiological Research 2024; 288: 127871 doi: 10.1016/j.micres.2024.127871
40
Jing Guo, Shao-Jun Yun, Jin-Ling Cao, Yan-Fen Cheng, Fei-Er Cheng, Cui-Ping Feng. Inhibitory effect of Sparassis latifolia polysaccharides on cariogenic bacteria as studied in-vitro simulated oral processing International Journal of Food Properties 2022; 25(1): 1099 doi: 10.1080/10942912.2022.2071292
41
Chwan-Li Shen, Julianna Maria Santos, Moamen M. Elmassry, Fang Chen, Guangchen Ji, Peyton Presto, Takaki Kiritoshi, Xiaobo Liu, Volker Neugebauer. Crosstalk Among Gut Microbiota, Fecal Metabolites, and Amygdala Neuropathology Genes After Ginger Polyphenol Administration in Female Rats with Neuropathic Pain: Evidence for Microbiota–Gut–Brain ConnectionNutrients 2025; 17(9): 1444 doi: 10.3390/nu17091444
42
Madhur Wyatt, K. Leigh Greathouse. Targeting Dietary and Microbial Tryptophan-Indole Metabolism as Therapeutic Approaches to Colon CancerNutrients 2021; 13(4): 1189 doi: 10.3390/nu13041189
43
Jing Li, Ai-hua Zhang, Fang-fang Wu, Xi-jun Wang. Alterations in the Gut Microbiota and Their Metabolites in Colorectal Cancer: Recent Progress and Future ProspectsFrontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.841552
44
Yi-jun Wu, Jing-fang Xiong, Cheng-nan Zhan, Hong Xu. Gut microbiota alterations in colorectal adenoma-carcinoma sequence based on 16S rRNA gene sequencing: A systematic review and meta-analysisMicrobial Pathogenesis 2024; 195: 106889 doi: 10.1016/j.micpath.2024.106889
45
Guadalupe Sánchez-Terrón, Remigio Martínez, David Morcuende, Mario Estévez. Deciphering the Physiological Responses to the Intake of Plant-Based Meat Analogues: On the Track of Microbiota and Biomarkers in Serum and UrineJournal of Agricultural and Food Chemistry 2025;  doi: 10.1021/acs.jafc.5c02799
46
Fei Wang, Meiyi Song, Xiya Lu, Xuefeng Zhu, Jiali Deng. Gut microbes in gastrointestinal cancersSeminars in Cancer Biology 2022; 86: 967 doi: 10.1016/j.semcancer.2021.03.037
47
Fatema Hersi, Sara M. Elgendy, Salma A. Al Shamma, Roa T. Altell, Omar Sadiek, Hany A. Omar. Cancer immunotherapy resistance: The impact of microbiome-derived short-chain fatty acids and other emerging metabolitesLife Sciences 2022; 300: 120573 doi: 10.1016/j.lfs.2022.120573
48
Hazrat Bilal, Muhammad Nadeen Khan, Sabir Khan, Muhammad Shafiq, Wenjie Fang, Yuebin Zeng, Yangzhong Guo, Xiaohui Li, Bing Zhao, Qiao-Li Lv, Bin Xu. Fungal Influences on Cancer Initiation, Progression, and Response to TreatmentCancer Research 2025; 85(3): 413 doi: 10.1158/0008-5472.CAN-24-1609
49
Lin Zhong, Seenivasan Boopathi, Bhagyalakshmi Purushothaman, Qiang Tu, Youming Zhang. Gut microbiota – indole-3-acetic acid axis in cancer: dual functions, mechanistic insights, and therapeutic potentialMicrobiological Research 2025; 300: 128293 doi: 10.1016/j.micres.2025.128293
50
Zexin Zhang, Dongting Li, Fengxi Xie, Gulizeba Muhetaer, Haibo Zhang. The cause-and-effect relationship between gut microbiota abundance and carcinoid syndrome: a bidirectional Mendelian randomization studyFrontiers in Microbiology 2023; 14 doi: 10.3389/fmicb.2023.1291699