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For: Yu ZC, Cen YX, Wu BH, Wei C, Xiong F, Li DF, Liu TT, Luo MH, Guo LL, Li YX, Wang LS, Wang JY, Yao J. Berberine prevents stress-induced gut inflammation and visceral hypersensitivity and reduces intestinal motility in rats. World J Gastroenterol 2019; 25(29): 3956-3971 [PMID: 31413530 DOI: 10.3748/wjg.v25.i29.3956]
URL: https://www.wjgnet.com/1007-9327/full/v25/i29/3956.htm
Number Citing Articles
1
Zhengwang Sun, Zirui He, Rujiao Liu, Zhe Zhang. Cation Lipid-Assisted PEG6-PLGA Polymer Nanoparticles Encapsulated Knocking Down Long ncRNAs Reverse Non-Coding RNA of Xist Through the Support Vector Machine Model to Regulate the Molecular Mechanisms of Gastric Cancer Cell Apoptosis. Journal of Biomedical Nanotechnology 2021; 17(7) doi: 10.1166/jbn.2021.3107
2
Zheng Yang, Mengni Bian, Junbing Ma, Yonghe Dong, Dan Yang, Min Qiu, Zhixiang Gao. Berberine regulates pulmonary inflammatory microenvironment and decreases collagen deposition in response to bleomycin‐induced pulmonary fibrosis in mice. Basic & Clinical Pharmacology & Toxicology 2023; 132(2) doi: 10.1111/bcpt.13818
3
Adrienne M. Antonson, Morgan V. Evans, Jeffrey D. Galley, Helen J. Chen, Therese A. Rajasekera, Sydney M. Lammers, Vanessa L. Hale, Michael T. Bailey, Tamar L. Gur. Unique maternal immune and functional microbial profiles during prenatal stress. Scientific Reports 2020; 10(1) doi: 10.1038/s41598-020-77265-x
4
Nazanin Momeni Roudsari, Naser-Aldin Lashgari, Saeideh Momtaz, Shaghayegh Abaft, Fatemeh Jamali, Pardis Safaiepour, Kiyana Narimisa, Gloria Jackson, Anusha Bishayee, Nima Rezaei, Amir Hossein Abdolghaffari, Anupam Bishayee. Inhibitors of the PI3K/Akt/mTOR Pathway in Prostate Cancer Chemoprevention and Intervention. Pharmaceutics 2021; 13(8) doi: 10.3390/pharmaceutics13081195
5
Linglin Tian, Yunuan Bai, Shiqi Wang, Changjian Wang, Jianping Gao, Jiangtao Zhou, Wenping Xiang. Codonopsis pilosula inulin-type fructan CPA ameliorates diarrhea-predominant irritable bowel syndrome via regulation of ER stress-induced autophagy and modulation of gut microbiota. Frontiers in Pharmacology 2026; 17 doi: 10.3389/fphar.2026.1715972
6
Ursula Wade, Domingo A. Pascual-Figal, Fazale Rabbani, Marie Ernst, Adelin Albert, Isabelle Janssens, Yvan Dierckxsens, Somia Iqtadar, Nisar A. Khokhar, Ayesha Kanwal, Amjad Khan. The Possible Synergistic Pharmacological Effect of an Oral Berberine (BBR) and Curcumin (CUR) Complementary Therapy Alleviates Symptoms of Irritable Bowel Syndrome (IBS): Results from a Real-Life, Routine Clinical Practice Settings-Based Study. Nutrients 2024; 16(8) doi: 10.3390/nu16081204
7
Ewa Dudzińska, Andreas M. Grabrucker, Paweł Kwiatkowski, Robert Sitarz, Monika Sienkiewicz. The Importance of Visceral Hypersensitivity in Irritable Bowel Syndrome—Plant Metabolites in IBS Treatment. Pharmaceuticals 2023; 16(10) doi: 10.3390/ph16101405
8
Na Ri Choi, Min Ji Kwon, Woo-Gyun Choi, Sang Chan Kim, Jae-Woo Park, Joo Hyun Nam, Byung Joo Kim. The traditional herbal medicines mixture, Banhasasim-tang, relieves the symptoms of irritable bowel syndrome via modulation of TRPA1, NaV1.5 and NaV1.7 channels. Journal of Ethnopharmacology 2023; 312 doi: 10.1016/j.jep.2023.116499
9
Sicong Li, Xin Liu, Xiaoran Chen, Lei Bi, Tae Jin lee. Research Progress on Anti‐Inflammatory Effects and Mechanisms of Alkaloids from Chinese Medical Herbs. Evidence-Based Complementary and Alternative Medicine 2020; 2020(1) doi: 10.1155/2020/1303524
10
Milad Ashrafizadeh, Masoud Najafi, Reza Mohammadinejad, Tahereh Farkhondeh, Saeed Samarghandian. Berberine Administration in Treatment of Colitis: A Review. Current Drug Targets 2020; 21(13) doi: 10.2174/1389450121666200621193758
11
Fang Cao, Weiyang Xia, Shengcheng Dai, Changkang Wang, Rui Shi, Yujie Yang, Cui Guo, Xue liang Xu, Jian Luo. Berberine: An inspiring resource for the treatment of colorectal diseases. Biomedicine & Pharmacotherapy 2023; 167 doi: 10.1016/j.biopha.2023.115571
12
Aiwen Feng, Shaosheng Su, Cheng Li, Yutian Kang, Jiasheng Qiu, Jun Zhou. Berberine decreases S100B generation to regulate gut vascular barrier permeability in mice with burn injury. Pharmaceutical Biology 2024; 62(1) doi: 10.1080/13880209.2023.2291679
13
Han Lin, Yunlong Lv, Huacheng Liu, Zheng Lin, Ning Zhu, Bingwu Huang. Baicalein alleviates chronic acute stress-induced irritable bowel syndrome-like symptoms in rats via modulating the ODC1/NF-κB pathway and oxidative stress. Biochemical and Biophysical Research Communications 2025; 771 doi: 10.1016/j.bbrc.2025.152058
14
Camila Bach, Carolina Silva Schiebel, Lara Luisa Valerio de Mello Braga, Ana Carolina Vieira Ulysséa Fernandes, Mariana Avancini, Gabriel Ferreira Fernandes, Jonatan Zaleski, Jessica Boschini D’Agostin, Daniele Maria-Ferreira. Natural products for the management of diarrhea: a systematic review of clinical efficacy, safety, and certainty of evidence. Frontiers in Pharmacology 2026; 17 doi: 10.3389/fphar.2026.1810632
15
Deepak Chandra Joshi, Neha Raina, Nirmal Joshi, Kajal Gurow, Jyoti Gwasakoti, Abhilasha Sood, Arpit Mehrotra, Hardeep Singh Tuli, Keshav Raj Paudel, Madhu Gupta. Current Landscape of Novel Therapeutic Agents and Drug Targets in Irritable Bowel Syndrome. Archiv der Pharmazie 2025; 358(11) doi: 10.1002/ardp.70133
16
Naser-Aldin Lashgari, Nazanin Momeni Roudsari, Saeideh Momtaz, Faezeh Niazi Shahraki, Nadia Zandi, Benyamin Pazoki, Mohammad Hosein Farzaei, Mehdi Ghasemi, Mohammad Abdollahi, Amir Hossein Abdolghaffari. Systematic Review on Herbal Preparations for Controlling Visceral Hypersensitivity in Functional Gastrointestinal Disorders. Current Pharmaceutical Biotechnology 2024; 25(13) doi: 10.2174/0113892010261502231102040149
17
Diya Ye, Yuting Hu, Ning Zhu, Weizhong Gu, Gao Long, Enfu Tao, Marong Fang, Mizu Jiang, Mirella Giovarelli. Exploratory Investigation of Intestinal Structure and Function after Stroke in Mice. Mediators of Inflammation 2021; 2021(1) doi: 10.1155/2021/1315797
18
Yulin Lu, Jingjing Huang, Yao Zhang, Zitong Huang, Weiming Yan, Tianran Zhou, Zhesheng Wang, Lu Liao, Hongying Cao, Bo Tan. Therapeutic Effects of Berberine Hydrochloride on Stress-Induced Diarrhea-Predominant Irritable Bowel Syndrome Rats by Inhibiting Neurotransmission in Colonic Smooth Muscle. Frontiers in Pharmacology 2021; 12 doi: 10.3389/fphar.2021.596686
19
奇梦 庞. Research Progress of Berberine in Treatment of Intestinal Diseases. Advances in Clinical Medicine 2024; 14(11) doi: 10.12677/acm.2024.14112838
20
Hanjie He, Jieming Qin, Ziteng Ma, Wenkai Sun, Wende Yan, Gongxiu He, Maoxun Yang, Dangquan Zhang. Highly efficient regeneration and medicinal component determination of Phellodendron chinense Schneid. In Vitro Cellular & Developmental Biology - Plant 2020; 56(6) doi: 10.1007/s11627-020-10080-1
21
İbrahim BAŞHAN. Effect of berberine on irritable bowel syndrome: A symptom-based review. International Journal of Plant Based Pharmaceuticals 2022;  doi: 10.55484/ijpbp.1084455
22
Xinlu Li, Jianfeng Chen, Wennuo Feng, Chao Wang, Minyu Chen, Yifan Li, Jinghong Chen, Xinwei Liu, Qiong Liu, Jing Tian. Berberine ameliorates iron levels and ferroptosis in the brain of 3 × Tg-AD mice. Phytomedicine 2023; 118 doi: 10.1016/j.phymed.2023.154962
23
Mengyao Cui, Ying Li, Tingting Zheng, Huan Chen, Jinrui Wang, Yifan Feng, Hanyi Ye, Zhengqi Dong, Geng Li. Efficacy and Molecular Mechanism of Quercetin on Constipation Induced by Berberine via Regulating Gut Microbiota. International Journal of Molecular Sciences 2024; 25(11) doi: 10.3390/ijms25116228
24
Mengmeng Zhang, Xu Wu, Huanqing Gao, Lin Zhang, Yao Li, Min Li, Chongbo Zhao, Peifeng Wei, Li Ou. Chinese Herbal Medicine for Irritable Bowel Syndrome: A Perspective of Local Immune Actions. The American Journal of Chinese Medicine 2024; 52(07) doi: 10.1142/S0192415X24500800
25
Yuejia Lan, Huan Wang, Jiasi Wu, Xianli Meng. Cytokine storm-calming property of the isoquinoline alkaloids in Coptis chinensis Franch. Frontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.973587
26
Laura López-Gómez, Ana Bagüés, José Antonio Uranga, Raquel Abalo. A Comprehensive Overview of Irritable Bowel Syndrome. 2020;  doi: 10.1016/B978-0-12-821324-7.00012-5
27
Yan Chen, Fuhao Chu, Jie Lin, Zeqi Su, Mengting Liao, Tao Li, Yuan Li, Nadia Johnson, Haocheng Zheng, Xia Ding. The mechanisms of action of WeiChang'An Pill (WCAP) treat diarrhoea-predominant irritable bowel syndrome (IBS-D) using network pharmacology approach and in vivo studies. Journal of Ethnopharmacology 2021; 275 doi: 10.1016/j.jep.2021.114119
28
Antonella Orlando, Guglielmina Chimienti, Maria Notarnicola, Francesco Russo. The Ketogenic Diet Improves Gut–Brain Axis in a Rat Model of Irritable Bowel Syndrome: Impact on 5-HT and BDNF Systems. International Journal of Molecular Sciences 2022; 23(3) doi: 10.3390/ijms23031098
29
Sihao Zhang, Danmei Tian, Zixuan Xia, Fengge Yang, Yanhui Chen, Zhihong Yao, Yi He, Xinglong Miao, Guirong Zhou, Xinsheng Yao, Jinshan Tang. Chang-Kang-Fang alleviates diarrhea predominant irritable bowel syndrome (IBS-D) through inhibiting TLR4/NF-κB/NLRP3 pathway. Journal of Ethnopharmacology 2024; 330 doi: 10.1016/j.jep.2024.118236
30
Sapana P. Bansod, Mohd Aslam Saifi, Shrilekha Chilvery, Nandkumar Doijad, Chandraiah Godugu. Berberine Attenuates Cerulein‐Induced Acute Pancreatitis by Modulating Nrf2/NOX2 Signaling Pathway via AMPK Activation. Environmental Toxicology 2025; 40(5) doi: 10.1002/tox.24468
31
Cui Zhu, Meifang Le, Zhentao He, Yinshan Bai, Jun Yang, Jinling Ye, Zhuang Chen, Zongyong Jiang. Dietary berberine supplementation improves growth performance and alleviates gut injury in weaned piglets by modulating ileal microbiota and metabolites. Food & Function 2023; 14(9) doi: 10.1039/D3FO01044A
32
Ying Xiong, Hong Wei, Chong Chen, Lu Jiao, Juan Zhang, Yonggang Tan, Li Zeng. Coptisine attenuates post‑infectious IBS via Nrf2‑dependent inhibition of the NLPR3 inflammasome. Molecular Medicine Reports 2022; 26(6) doi: 10.3892/mmr.2022.12879
33
Wei Ke, Jinjun Wu, Hongbin Li, Siyu Huang, Huibiao Li, Yongfu Wang, Yingxiu Wu, Jie Yuan, Shuncong Zhang, Hongmei Tang, Kaijun Lei. Network pharmacology and experimental validation to explore the mechanism of Changji'an formula against irritable bowel syndrome with predominant diarrhea. Heliyon 2024; 10(12) doi: 10.1016/j.heliyon.2024.e33102
34
Mengnan Huang, Yuanyuan He, Lin Tian, Lu Yu, Qi Cheng, Zhu Li, Lina Gao, Shan Gao, Chunquan Yu. Gut microbiota-SCFAs-brain axis associated with the antidepressant activity of berberine in CUMS rats. Journal of Affective Disorders 2023; 325 doi: 10.1016/j.jad.2022.12.166
35
Xin Gao, Tingting Xu, Yunlin Shi, Zhongzhong Bai, Jun Zhou, Hongli Wu, Fei Cao, Ping Wei. Production of fermentable sugar, ethanol, D-lactic acid, and biochar from starch-rich traditional Chinese medicine decoction residues. Biomass Conversion and Biorefinery 2024; 14(24) doi: 10.1007/s13399-023-04997-x
36
Maite Casado-Bedmar, Åsa V. Keita. Potential neuro-immune therapeutic targets in irritable bowel syndrome. Therapeutic Advances in Gastroenterology 2020; 13 doi: 10.1177/1756284820910630
37
Bosen Zhang, Ziye Zhang, Lei Feng, Zhiyong Hu, Ruina Zhai. Effects of Supplementing Yeast Culture to Prepartum Cows Under Heat Stress on the Jejunal Microbiota and Metabolites of Calves. Animals 2026; 16(4) doi: 10.3390/ani16040668
38
Saeed Mohammadian Haftcheshmeh, Maliheh Abedi, Kazem Mashayekhi, Mohammad Javad Mousavi, Jamshid Gholizadeh Navashenaq, Asadollah Mohammadi, Amir Abbas Momtazi‐Borojeni. Berberine as a natural modulator of inflammatory signaling pathways in the immune system: Focus on NF‐κB, JAK/STAT, and MAPK signaling pathways. Phytotherapy Research 2022; 36(3) doi: 10.1002/ptr.7407
39
Bifang Yao, Zhengxiang Long, Xiaojiao Lin, Guangqiang Chen, Xiaoyu Li, Ziqi Ye, Jiahong Liu. The potential value of the use of berberine in depression: a systematic review and meta-analysis of preclinical studies. Frontiers in Pharmacology 2025; 16 doi: 10.3389/fphar.2025.1664784
40
Xue Zhou, Meng Zeng, Fujiao Huang, Gang Qin, Zhangyong Song, Fangyan Liu. The potential role of plant secondary metabolites on antifungal and immunomodulatory effect. Applied Microbiology and Biotechnology 2023; 107(14) doi: 10.1007/s00253-023-12601-5