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For: Hentic O, Dreyer C, Rebours V, Zappa M, Lévy P, Raymond E, Ruszniewski P, Hammel P. Gemcitabine in elderly patients with advanced pancreatic cancer. World J Gastroenterol 2011; 17(30): 3497-3502 [PMID: 21941416 DOI: 10.3748/wjg.v17.i30.3497]
URL: https://www.wjgnet.com/1007-9327/full/v17/i30/3497.htm
Number Citing Articles
1
Lynda R. Corrigan, Dara M. Bracken-Clarke, Anne M. Horgan. The challenge of treating older patients with pancreaticobiliary malignancies. Current Problems in Cancer 2018; 42(1) doi: 10.1016/j.currproblcancer.2018.01.015
2
Minas Baltatzis, Maria Grazia Rodriquenz, Ajith K. Siriwardena, Nicola De Liguori Carino. Contemporary management of pancreas cancer in older people. European Journal of Surgical Oncology 2021; 47(3) doi: 10.1016/j.ejso.2020.08.007
3
Salah Mabrouk Khallaf, Elsayed Mostafa Ali, Ahmed M. Maklad, Mohamed Medhat Samir, Anwar Tawfik Amin, Muhammad Abbas El-Masry, Mona M. Sayed, Dalia Osama. In Frail Elderly Patients, Low-Dose Gemcitabine over 6-Hour Infusion Is Equally Effective and Less Toxic Than the Standard Gemcitabine Protocol for Advanced Pancreatic Adenocarcinoma: A Randomized Phase II Trial. Journal of Cancer Therapy 2020; 11(03) doi: 10.4236/jct.2020.113011
4
Lydia van der Geest, Johanneke Portielje, Hanneke Wilmink. Textbook of Pancreatic Cancer. 2021;  doi: 10.1007/978-3-030-53786-9_39
5
Satoshi Kobayashi, Makoto Ueno, Masafumi Ikeda, Masato Ozaka, Yusuke Sano, Akane Hirotani, Yuichiro Tozuka, Taito Fukushima, Shun Tezuka, Satoshi Moriya, Kumiko Umemoto, Kazuo Watanabe, Mitsuhito Sasaki, Yusuke Hashimoto, Hiroshi Imaoka, Izumi Ohno, Shuichi Mitsunaga, Ikuhiro Yamada, Takashi Sasaki, Naoki Sasahira, Manabu Morimoto. A Multicenter Retrospective Study of Gemcitabine Plus Nab-Paclitaxel for Elderly Patients With Advanced Pancreatic Cancer. Pancreas 2020; 49(2) doi: 10.1097/MPA.0000000000001484
6
Aurélien Lambert, Lilian Schwarz, Ivan Borbath, Aline Henry, Jean-Luc Van Laethem, David Malka, Michel Ducreux, Thierry Conroy. An update on treatment options for pancreatic adenocarcinoma. Therapeutic Advances in Medical Oncology 2019; 11 doi: 10.1177/1758835919875568
7
Jennifer Y. Wo, Theodore S. Hong, Lisa A. Kachnic. Impact of Age and Comorbidities on the Treatment of Gastrointestinal Malignancies. Seminars in Radiation Oncology 2012; 22(4) doi: 10.1016/j.semradonc.2012.05.008
8
Taira Kuroda, Teru Kumagi, Tomoyuki Yokota, Nobuaki Azemoto, Aki Hasebe, Hirotaka Seike, Mari Nishiyama, Nobu Inada, Naozumi Shibata, Hideki Miyata, Tomoe Kawamura, Yusuke Imai, Akiko Ueno-Toshimori, Yoshinori Tanaka, Takashi Terao, Yoshiki Imamura, Mitsuhito Koizumi, Hirofumi Yamanishi, Yoshinori Ohno, Yoichi Hiasa. Efficacy of chemotherapy in elderly patients with unresectable pancreatic cancer: a multicenter review of 895 patients. BMC Gastroenterology 2017; 17(1) doi: 10.1186/s12876-017-0623-8
9
A. N. Khitrova, L. V. Bolotina, A. L. Kornietskaya, L. I. Moskvicheva. High-intensity focused ultrasound therapy as part of combined treatment for inoperable pancreatic cancer. Onkologiya. Zhurnal imeni P.A.Gertsena 2020; 9(1) doi: 10.17116/onkolog2020901150
10
Byung Soo Kwan, Ok Jae Lee, Hyun Jin Kim, Kwang Min Kim, Sang Goon Shim, Dae Hyeon Cho, Sung Min Kong, Jun Young Kim, Jun Ho Ji. Efficacy and Safety of Chemotherapy in Elderly Patients with Unresectable Pancreatic Cancer. Journal of Clinical Medicine 2023; 12(9) doi: 10.3390/jcm12093334
11
A M Nagrial, D K Chang, N Q Nguyen, A L Johns, L A Chantrill, J L Humphris, V T Chin, J S Samra, A J Gill, M Pajic, M Pinese, E K Colvin, C J Scarlett, A Chou, J G Kench, R L Sutherland, L G Horvath, A V Biankin. Adjuvant chemotherapy in elderly patients with pancreatic cancer. British Journal of Cancer 2014; 110(2) doi: 10.1038/bjc.2013.722
12
Sandrine Oziel-Taieb, Marjorie Faure, Marine Gilabert, Aurélie Autret, Olivier Turrini, Laurence Moureau-Zabotto, Marc Giovannini, Frederique Rousseau, Jean-Luc Raoul. Treatment of Pancreatic Adenocarcinoma in Elderly Patients over 75 Years of Age: A Retrospective Series of 129 Patients. Journal of Gastrointestinal Cancer 2016; 47(1) doi: 10.1007/s12029-015-9774-4
13
Pascal Hammel, Cindy Neuzillet, Sihem Bendaoud, Céline Lekhal, Louis de Mestier, Olivia Hentic. Traitement médical du cancer du pancréas : en 10 ans, enfin des progrès. Bulletin du Cancer 2015; 102(6) doi: 10.1016/S0007-4551(15)31219-4
14
Nicolai Härtel, Felix Rückert. Geriatrische Onkologie. 2016;  doi: 10.1007/978-3-662-49083-9_26-1
15
A. R. Lewis, C. Cipriano, X. Wang, R. Ward, A. Fitzpatrick, A. R. M. Scott, A. Rashed, H. Raja, A. Lamarca, R. A. Hubner, J. W. Valle, M. G. McNamara. Outcomes in patients ≥ 80 years with a diagnosis of a hepatopancreaticobiliary (HPB) malignancy. Medical Oncology 2019; 36(10) doi: 10.1007/s12032-019-1310-0
16
Satoshi KOBAYASHI, Makoto UENO, Junji FURUSE. Treatment for patients with pancreatic cancer in a super-aging society. Suizo 2024; 39(1) doi: 10.2958/suizo.39.26
17
Lydia G. M. van der Geest, Nadia Haj Mohammad, Marc G. H. Besselink, Valery E. P. P. Lemmens, Johanneke E. A. Portielje, Hanneke W. M. van Laarhoven, J. (Hanneke) W. Wilmink. Nationwide trends in chemotherapy use and survival of elderly patients with metastatic pancreatic cancer. Cancer Medicine 2017; 6(12) doi: 10.1002/cam4.1240
18
Mona Mohmed Eddfair, Othman Abdulrahman, Omar Alqawi, Mourad Assidi, Abdelbaset Buhmeida, Abdulfattah Elturki, Abdalla Jebriel, Mohamed Elfagieh, Eramah Ermiah. Correlations of demographical and clinicopathological features with patient outcome of pancreatic ductal adenocarcinoma: A retrospective study (2010-2018) from a Libyan Cohort. Journal of Cancer Research and Therapeutics 2023; 19(3) doi: 10.4103/jcrt.jcrt_1778_21
19
John R. Ogden, Hao Xie, Wen Wee Ma, Joleen M. Hubbard. The Management of Older Adults with Pancreatic Adenocarcinoma. Geriatrics 2018; 3(4) doi: 10.3390/geriatrics3040085
20
FARUK TAS, FATMA SEN, SERKAN KESKIN, LEYLA KILIC, IBRAHIM YILDIZ. Prognostic factors in metastatic pancreatic cancer: Older patients are associated with reduced overall survival. Molecular and Clinical Oncology 2013; 1(4) doi: 10.3892/mco.2013.131
21
Jean-Luc Raoul, Olivier Turrini, Anthony Gonçalves, Marine Gilabert, Marc Giovannini, Frederique Rousseau. Why is Pancreatic Cancer Difficult to Treat in the Elderly?. Aging Health 2012; 8(3) doi: 10.2217/ahe.12.20
22
Maya N. White, Efrat Dotan, Paul J. Catalano, Dana B. Cardin, Jordan D. Berlin. Advanced pancreatic cancer clinical trials: The continued underrepresentation of older patients. Journal of Geriatric Oncology 2019; 10(4) doi: 10.1016/j.jgo.2018.11.001
23
Josenon Gomes Costa, Victor Hugo Fonseca de Jesus, Marcos Pedro Guedes Camandaroba, Aldo Lourenço Abbade Dettino. Characteristics and survival of older patients with metastatic pancreatic cancer: a retrospective analysis of the AC Camargo Cancer Center experience. Therapeutic Advances in Medical Oncology 2019; 11 doi: 10.1177/1758835919874650
24
T. Macarulla, A. Carrato, R. Díaz, A. García, B. Laquente, J. Sastre, R. Álvarez, A. Muñoz, M. Hidalgo. Management and supportive treatment of frail patients with metastatic pancreatic cancer. Journal of Geriatric Oncology 2019; 10(3) doi: 10.1016/j.jgo.2018.06.005
25
Francesca M. Dimou, Taylor S. Riall. Difficult Decisions in Hepatobiliary and Pancreatic Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach 2016;  doi: 10.1007/978-3-319-27365-5_58
26
Marina Macchini, Marta Chiaravalli, Silvia Zanon, Umberto Peretti, Elena Mazza, Luca Gianni, Michele Reni. Chemotherapy in elderly patients with pancreatic cancer: Efficacy, feasibility and future perspectives. Cancer Treatment Reviews 2019; 72 doi: 10.1016/j.ctrv.2018.10.013
27
Kangju Son, Byung Kyu Park, Chan Su Park, Joung-Ho Han, Kyong Joo Lee. Effects of Chemotherapy on Survival Outcomes in Older Patients with Metastatic Pancreatic Cancer: A Nationwide Population-Based Study. Gut and Liver 2026; 20(5) doi: 10.5009/gnl250551
28
Hyunsoo Kim, Joonho Park, Joseph I. Wang, Youngsoo Kim. Recent advances in proteomic profiling of pancreatic ductal adenocarcinoma and the road ahead. Expert Review of Proteomics 2017; 14(11) doi: 10.1080/14789450.2017.1382356
29
30
Louise S. Rasmussen, Claus W. Fristrup, Benny V. Jensen, Per Pfeiffer, Britta Weber, Mette K. Yilmaz, Laurids Ø. Poulsen, Morten Ladekarl, Kell Østerlind, Jim S. Larsen, Halla Skuladottir, Martin Bøgsted, Ursula G. Falkmer. Patterns of Palliative Chemotherapy and Survival in Patients With Pancreatic Cancer Focusing on Age. Pancreas 2021; 50(5) doi: 10.1097/MPA.0000000000001833
31
Flore Pignon, Anthony Turpin, Olivia Hentic, Romain Coriat, Emma Salmon, Isabelle Baumgaertner, Nicolas Bertrand, Philippe Lévy, Vinciane Rebours, Pascal Hammel, Louis de Mestier. Efficacy and tolerance of gemcitabine and nab-paclitaxel in elderly patients with advanced pancreatic ductal adenocarcinoma. Pancreatology 2021; 21(6) doi: 10.1016/j.pan.2021.05.006
32
Carolyn H Kim, Diane C Ling, Rodney E Wegner, John C Flickinger, Dwight E Heron, Herbert Zeh, Arthur J Moser, Steven A Burton. Stereotactic body radiotherapy in the treatment of Pancreatic Adenocarcinoma in elderly patients. Radiation Oncology 2013; 8(1) doi: 10.1186/1748-717X-8-240
33
Hiroshi Imaoka, Tadayuki Kou, Masao Tanaka, Shinichi Egawa, Nobumasa Mizuno, Susumu Hijioka, Kazuo Hara, Shujiro Yazumi, Yasuhiro Shimizu, Kenji Yamao. Clinical outcome of elderly patients with unresectable pancreatic cancer treated with gemcitabine plus S-1, S-1 alone, or gemcitabine alone: Subgroup analysis of a randomised phase III trial, GEST study.. European Journal of Cancer 2016; 54 doi: 10.1016/j.ejca.2015.11.002
34
Josefina Salazar, Javier Bracchiglione, Roberto Acosta-Dighero, Nicolas Meza, Adriana-G. Meade, María Jesús Quintana, Carolina Requeijo, Gerardo Rodríguez-Grijalva, Marilina Santero, Anna Selva, Ivan Solà, Xavier Bonfill, Karla Salas, Alba Antequera, Ariadna Auladell-Rispau, Gerard Urrútia, Pamela Meinardi, Juan Irassar, Daniel Simancas, Rosario Dorantes, Angela Merchán, Yahveth Cantero, Edgar Hernandez, Miguel Sugrañes. Systemic oncological treatments in patients with advanced pancreatic cancer: a scoping review and evidence map. Supportive Care in Cancer 2023; 31(2) doi: 10.1007/s00520-022-07564-8
35
Satoshi Kobayashi, Makoto Ueno, Hiroshi Ishii, Junji Furuse. Management of elderly patients with unresectable pancreatic cancer. Japanese Journal of Clinical Oncology 2022;  doi: 10.1093/jjco/hyac101
36
Raphaël Maréchal, Anne Demols, Jean-Luc Van Laethem. Adjuvant Pharmacotherapy in the Management of Elderly Patients with Pancreatic Cancer. Drugs & Aging 2013; 30(3) doi: 10.1007/s40266-013-0049-0
37
Sohei Satoi, Tomohisa Yamamoto, Kazushige Uchida, Tsutomu Fujii, Toshifumi Kin, Satoshi Hirano, Keiji Hanada, Takao Itoi, Yoshiaki Murakami, Hisato Igarashi, Hidetoshi Eguchi, Tamotsu Kuroki, Yasuhiro Shimizu, Masaji Tani, Satoshi Tanno, Yoshihisa Tsuji, Yoshiki Hirooka, Atsushi Masamune, Toshio Shimokawa, Hiroki Yamaue, Kazuichi Okazaki. Optimal Treatment for Octogenarians With Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma. Pancreas 2020; 49(6) doi: 10.1097/MPA.0000000000001579
38
Alison Backen, Angela Lamarca, Richard A. Hubner, Mairéad G. McNamara, Juan W. Valle. HPB cancers in older patients | inclusion of older/senior patients in clinical trials. European Journal of Surgical Oncology 2021; 47(3) doi: 10.1016/j.ejso.2020.11.002
39
Daneng Li, Marinela Capanu, Kenneth H. Yu, Maeve A. Lowery, David P. Kelsen, Eileen M. O'Reilly. Treatment, Outcomes, and Clinical Trial Participation in Elderly Patients With Metastatic Pancreas Adenocarcinoma. Clinical Colorectal Cancer 2015; 14(4) doi: 10.1016/j.clcc.2015.05.005
40
Marina Macchini, Marta Chiaravalli, Chiara Pircher, Silvia Zanon, Umberto Peretti, Elena Mazza, Maria Maddalena Valente, Clara Fugazza, Luca Gianni, Michele Reni. Multidrug regimens for treatment of older patients with metastatic pancreatic cancer. Digestive and Liver Disease 2021; 53(1) doi: 10.1016/j.dld.2020.06.006
41
Xiang Li, Da-bing Huang, Qi Zhang, Cheng-xiang Guo, Qi-han Fu, Xiao-chen Zhang, Tian-Yu Tang, Wei Su, Yi-Wen Chen, Wei Chen, Tao Ma, Shun-Liang Gao, Ri-Sheng Que, Xue-Li Bai, Ting-Bo Liang. The efficacy and toxicity of chemotherapy in the elderly with advanced pancreatic cancer. Pancreatology 2020; 20(1) doi: 10.1016/j.pan.2019.11.012
42
Jonathan J. Hue, Katherine Bingmer, Kavin Sugumar, Lee M. Ocuin, Luke D. Rothermel, Jordan M. Winter, John B. Ammori, Jeffrey M. Hardacre. Mortality and Survival Among Octogenarians with Localized Pancreatic Head Cancer: a National Cancer Database Analysis. Journal of Gastrointestinal Surgery 2021; 25(10) doi: 10.1007/s11605-021-04949-8
43
Nicolai Härtel, Felix Rückert. Geriatrische Onkologie. 2018;  doi: 10.1007/978-3-662-48727-3_26
44
Philip A. Sutera, Mark E. Bernard, Hong Wang, Dwight E. Heron. Prognostic Factors for Elderly Patients Treated With Stereotactic Body Radiation Therapy for Pancreatic Adenocarcinoma. Frontiers in Oncology 2018; 8 doi: 10.3389/fonc.2018.00282
45
Jie Zeng, Ying Xiong, Long-bo Zhang, Jing-de Ruan, Wei Wu, Wei-jia Sun. The Antitumor Activity of Recombinant Antitumor Antiviral Protein and the Associated Molecular Mechanism in Pancreatic Tumor Cells. Cancer Biotherapy and Radiopharmaceuticals 2012; 27(7) doi: 10.1089/cbr.2012.1166
46
Fan Huang, Ashani T. Weeraratna. Age-Related Metabolic Reprogramming in Cancer Cell Plasticity.  Annual Review of Cancer Biology 2026; 10(1) doi: 10.1146/annurev-cancerbio-070524-040250