BPG is committed to discovery and dissemination of knowledge
Cited by in CrossRef
Number Cited Articles
1
Francesco Crea, Stefania Nobili, Elisa Paolicchi, Gabriele Perrone, Cristina Napoli, Ida Landini, Romano Danesi, Enrico Mini. Epigenetics and chemoresistance in colorectal cancer: An opportunity for treatment tailoring and novel therapeutic strategiesDrug Resistance Updates 2011; 14(6): 280 doi: 10.1016/j.drup.2011.08.001
2
Carmen Salguero-Aranda, Daniel Sancho-Mensat. Clinical implications of STAT6 mRNA and protein knockdown in human colon adenocarcinoma cell line, HT-29Colorectal Cancer 2019; 8(1): CRC09 doi: 10.2217/crc-2019-0004
3
Kai-Yuan Lin, Chein Tai, Jung-Chin Hsu, Chien-Feng Li, Chia-Lang Fang, Hsi-Chin Lai, You-Cheng Hseu, Yi-Feng Lin, Yih-Huei Uen, Terence Lee. Overexpression of Nuclear Protein Kinase CK2 α Catalytic Subunit (CK2α) as a Poor Prognosticator in Human Colorectal CancerPLoS ONE 2011; 6(2): e17193 doi: 10.1371/journal.pone.0017193
4
H. Tamagawa, T. Oshima, M. Numata, N. Yamamoto, M. Shiozawa, S. Morinaga, Y. Nakamura, M. Yoshihara, Y. Sakuma, Y. Kameda, M. Akaike, N. Yukawa, Y. Rino, M. Masuda, Y. Miyagi. Global histone modification of H3K27 correlates with the outcomes in patients with metachronous liver metastasis of colorectal cancerEuropean Journal of Surgical Oncology (EJSO) 2013; 39(6): 655 doi: 10.1016/j.ejso.2013.02.023
5
Tian Qing, Zhang Yamin, Wang Guijie, Jin Yan, Shen Zhongyang. STAT6 silencing induces hepatocellular carcinoma-derived cell apoptosis and growth inhibition by decreasing the RANKL expressionBiomedicine & Pharmacotherapy 2017; 92: 1 doi: 10.1016/j.biopha.2017.05.029
6
Laura Vilorio-Marqués, Vicente Martín, Cristina Diez-Tascón, María Francisca González-Sevilla, Tania Fernández-Villa, Emiliano Honrado, Veronica Davila-Batista, Antonio J. Molina. The role of EZH2 in overall survival of colorectal cancer: a meta-analysisScientific Reports 2017; 7(1) doi: 10.1038/s41598-017-13670-z
7
Shuling Chen, Lixia Huang, Kaiyu Sun, Dexi Wu, Minrui Li, Manying Li, Bihui Zhong, Minhu Chen, Shenghong Zhang, Rossella Rota. Enhancer of Zeste Homolog 2 as an Independent Prognostic Marker for Cancer: A Meta-AnalysisPLOS ONE 2015; 10(5): e0125480 doi: 10.1371/journal.pone.0125480
8
Tao Huang, Chengyuan Lin, Linda L. D. Zhong, Ling Zhao, Ge Zhang, Aiping Lu, Jiang Wu, Zhaoxiang Bian. Targeting histone methylation for colorectal cancerTherapeutic Advances in Gastroenterology 2017; 10(1): 114 doi: 10.1177/1756283X16671287
9
Claudio Rizzi, Palmina Cataldi, Aldo Iop, Miriam Isola, Riccardo Sgarra, Guidalberto Manfioletti, Vincenzo Giancotti. The expression of the high-mobility group A2 protein in colorectal cancer and surrounding fibroblasts is linked to tumor invasivenessHuman Pathology 2013; 44(1): 122 doi: 10.1016/j.humpath.2012.05.001
10
Yannick Verhoeven, Sam Tilborghs, Julie Jacobs, Jorrit De Waele, Delphine Quatannens, Christophe Deben, Hans Prenen, Patrick Pauwels, Xuan Bich Trinh, An Wouters, Evelien L.J. Smits, Filip Lardon, Peter A. van Dam. The potential and controversy of targeting STAT family members in cancerSeminars in Cancer Biology 2020; 60: 41 doi: 10.1016/j.semcancer.2019.10.002
11
Samar M. Abdel Raouf, Taiseer R. Ibrahim, Lobna A. Abdelaziz, Mohamed I. Farid, Salem Y Mohamed. Prognostic Value of TWIST1 and EZH2 Expression in Colon CancerJournal of Gastrointestinal Cancer 2019;  doi: 10.1007/s12029-019-00344-4
12
Fábio Pereira, Antonio Barbáchano, Prashant K. Singh, Moray J. Campbell, Alberto Muñoz, María Jesús Larriba. Vitamin D has wide regulatory effects on histone demethylase genesCell Cycle 2012; 11(6): 1081 doi: 10.4161/cc.11.6.19508
13
Tao Jiang, Yan Wang, Fei Zhou, Guanghui Gao, Shengxiang Ren, Caicun Zhou. Prognostic value of high EZH2 expression in patients with different types of cancer: a systematic review with meta-analysisOncotarget 2016; 7(4): 4584 doi: 10.18632/oncotarget.6612
14
Mozhdeh Zamani, Seyed Vahid Hosseini, Pooneh Mokarram. Epigenetic biomarkers in colorectal cancer: premises and prospectsBiomarkers 2018; 23(2): 105 doi: 10.1080/1354750X.2016.1252961
15
Cuiping Fu, Liyan Jiang, Shengyu Hao, Zilong Liu, Suling Ding, Weiwei Zhang, Xiangdong Yang, Shanqun Li. Activation of the IL-4/STAT6 Signaling Pathway Promotes Lung Cancer Progression by Increasing M2 Myeloid CellsFrontiers in Immunology 2019; 10 doi: 10.3389/fimmu.2019.02638
16
Lucy Jankova, Owen F. Dent, Mark P. Molloy, Charles Chan, Pierre H. Chapuis, Viive M. Howell, Stephen J. Clarke. Reporting in studies of protein biomarkers of prognosis in colorectal cancer in relation to the REMARK guidelinesPROTEOMICS - Clinical Applications 2015; 9(11-12): 1078 doi: 10.1002/prca.201400177
17
Xinhua Wang, Hongqing Zhao, Lei Lv, Liang Bao, Xun Wang, Shuguang Han. Prognostic Significance of EZH2 Expression in Non-Small Cell Lung Cancer: A Meta-analysisScientific Reports 2016; 6(1) doi: 10.1038/srep19239
18
Jingchun Qin, Bin Wen, Yuqi Liang, Weitao Yu, Huixuan Li. Histone Modifications and their Role in Colorectal Cancer (Review)Pathology & Oncology Research 2019;  doi: 10.1007/s12253-019-00663-8
19
Francesco Crea, Lorenzo Fornaro, Gianluca Masi, Alfredo Falcone, Romano Danesi, William Farrar. Faithful Markers of Circulating Cancer Stem Cells: Is CD133 Sufficient for Validation in Clinics?Journal of Clinical Oncology 2011; 29(25): 3487 doi: 10.1200/JCO.2011.37.0122
20
M Koppens, M van Lohuizen. Context-dependent actions of Polycomb repressors in cancerOncogene 2016; 35(11): 1341 doi: 10.1038/onc.2015.195
21
Stanleyson V. Hato, I. Jolanda M. de Vries, W. Joost Lesterhuis. STATing the importance of immune modulation by platinum chemotherapeuticsOncoImmunology 2012; 1(2): 234 doi: 10.4161/onci.1.2.18126
22
Xin Tang, Wenwei Cai, Jing Cheng, Ping Lu, Shaojun Ma, Chaoting Chen, Yi Chen, Yun Sun, Caofeng Wang, Ping Hu, Xiaomin Lv, G. Sun, Yu Wang, Jing Sheng. The histone H3 lysine-27 demethylase UTX plays a critical role in colorectal cancer cell proliferationCancer Cell International 2019; 19(1) doi: 10.1186/s12935-019-0841-y
23
Yan-Long Liu, Xu Gao, Yang Jiang, Gan Zhang, Zi-Cheng Sun, Bin-Bin Cui, Yan-Mei Yang. Expression and clinicopathological significance of EED, SUZ12 and EZH2 mRNA in colorectal cancerJournal of Cancer Research and Clinical Oncology 2015; 141(4): 661 doi: 10.1007/s00432-014-1854-5
24
Li Jiang, Xu-Hai Zhao, Yin-Ling Mao, Jun-Feng Wang, Hui-Jun Zheng, Qing-Shan You. Long non-coding RNA RP11-468E2.5 curtails colorectal cancer cell proliferation and stimulates apoptosis via the JAK/STAT signaling pathway by targeting STAT5 and STAT6Journal of Experimental & Clinical Cancer Research 2019; 38(1) doi: 10.1186/s13046-019-1428-0
25
Yong Jin Cho, Soo Hee Kim, Eun Kyung Kim, Jung Woo Han, Kyoo-Ho Shin, Hyuk Hu, Kyung Sik Kim, Young Deuk Choi, Sunghoon Kim, Young Han Lee, Jin-Suck Suh, Joong Bae Ahn, Hyun Cheol Chung, Sung Hoon Noh, Sun Young Rha, Sung-Taek Jung, Hyo Song Kim. Prognostic implications of polycomb proteins ezh2, suz12, and eed1 and histone modification by H3K27me3 in sarcomaBMC Cancer 2018; 18(1) doi: 10.1186/s12885-018-4066-6
26
Rosai and Ackerman's Surgical Pathology2011; : 37 doi: 10.1016/B978-0-323-06969-4.00023-4
27
Martijn AJ Koppens, Gergana Bounova, Paulien Cornelissen-Steijger, Nienke de Vries, Owen J Sansom, Lodewyk FA Wessels, Maarten van Lohuizen. Large variety in a panel of human colon cancer organoids in response to EZH2 inhibitionOncotarget 2016; 7(43): 69816 doi: 10.18632/oncotarget.12002
28
Bin Xu, Samuel Abourbih, Kanishka Sircar, Wassim Kassouf, Jose Joao Mansure, Armen Aprikian, Simon Tanguay, Fadi Brimo. Enhancer of Zeste Homolog 2 Expression Is Associated With Metastasis and Adverse Clinical Outcome in Clear Cell Renal Cell Carcinoma: A Comparative Study and Review of the LiteratureArchives of Pathology & Laboratory Medicine 2013; 137(10): 1326 doi: 10.5858/arpa.2012-0525-OA
29
Antonios N. Gargalionis, Christina Piperi, Christos Adamopoulos, Athanasios G. Papavassiliou. Histone modifications as a pathogenic mechanism of colorectal tumorigenesisThe International Journal of Biochemistry & Cell Biology 2012; 44(8): 1276 doi: 10.1016/j.biocel.2012.05.002
30
Saisai Li, Bo Sheng, Menghuang Zhao, Qi Shen, Haiyan Zhu, Xueqiong Zhu. The prognostic values of signal transducers activators of transcription family in ovarian cancerBioscience Reports 2017; 37(4) doi: 10.1042/BSR20170650
31
Hisao Kano, Tadatoshi Takayama, Yutaka Midorikawa, Hiroki Nagase. Promoter hypomethylation of RAR-related orphan receptor α 1 is correlated with unfavorable clinicopathological features in patients with colorectal cancerBioScience Trends 2016; 10(3): 202 doi: 10.5582/bst.2016.01097
32
Lamia Abd Al Kader, Takashi Oka, Katsuyoshi Takata, Xu Sun, Hiaki Sato, Ichiro Murakami, Tomohiro Toji, Akihiro Manabe, Hiroshi Kimura, Tadashi Yoshino. In aggressive variants of non-Hodgkin lymphomas, Ezh2 is strongly expressed and polycomb repressive complex PRC1.4 dominates over PRC1.2Virchows Archiv 2013; 463(5): 697 doi: 10.1007/s00428-013-1428-y
33
Hye Lim Lee, Mi Hee Park, Ju Kyoung Song, Yu Yeon Jung, Youngsoo Kim, Kyung Bo Kim, Dae Yeon Hwang, Do Young Yoon, Min Jong Song, Sang Bae Han, Jin Tae Hong. Tumor growth suppressive effect of IL-4 through p21-mediated activation of STAT6 in IL-4Rα overexpressed melanoma modelsOncotarget 2016; 7(17): 23425 doi: 10.18632/oncotarget.8111
34
Hisae Iinuma, Toshiaki Watanabe, Koshi Mimori, Junko Tamura, Miki Adachi, Naoko Hayashi, Keijiro Nozawa, Soichiro Ishihara, Keiji Matsuda, Hideo Baba, Ryoji Fukushima, Kota Okinaga, Mitsuru Sasako, Masaki Mori. Reply to F. Crea et alJournal of Clinical Oncology 2011; 29(25): 3488 doi: 10.1200/JCO.2011.37.2276
35
Qi Zhang, Qi Han, Jie Zi, Jinlong Ma, Huihui Song, Yulu Tian, Mary McGrath, Chunhua Song, Zheng Ge. Mutations in EZH2 are associated with poor prognosis for patients with myeloid neoplasmsGenes & Diseases 2019; 6(3): 276 doi: 10.1016/j.gendis.2019.05.001
36
Jiaqiu Li, Hongchuan Jin, Xian Wang. Epigenetic Biomarkers: Potential Applications in Gastrointestinal CancersISRN Gastroenterology 2014; 2014: 1 doi: 10.1155/2014/464015
37
Lamia Abdalkader, Takashi Oka, Katsuyoshi Takata, Hiaki Sato, Ichiro Murakami, Arie P. Otte, Tadashi Yoshino. Aberrant differential expression of EZH1 and EZH2 in Polycomb repressive complex 2 among B- and T/NK-cell neoplasmsPathology 2016; 48(5): 467 doi: 10.1016/j.pathol.2016.05.002
38
Yawei Wang, Fang Gao, Meng Zhao, Bing Li, Dan Xing, Jie Wang, Yang Yang. Prognostic significance of EZH2 expression in patients with oesophageal cancer: a meta-analysisJournal of Cellular and Molecular Medicine 2016; 20(5): 836 doi: 10.1111/jcmm.12791
39
Lukas F. Mager, Marie-Hélène Wasmer, Tilman T. Rau, Philippe Krebs. Cytokine-Induced Modulation of Colorectal CancerFrontiers in Oncology 2016; 6 doi: 10.3389/fonc.2016.00096
40
Chun-Mao Lin, Chia-Lang Fang, You-Cheng Hseu, Chun-Liang Chen, Jin-Wun Wang, Sheng-Lung Hsu, Ming-Dao Tu, Shih-Ting Hung, Chein Tai, Yih-Huei Uen, Kai-Yuan Lin, Irina V. Lebedeva. Clinical and Prognostic Implications of Transcription Factor SOX4 in Patients with Colon CancerPLoS ONE 2013; 8(6): e67128 doi: 10.1371/journal.pone.0067128
41
Antja-Voy Hartley, Matthew Martin, Tao Lu. Advances in the Molecular Understanding of Colorectal Cancer2019;  doi: 10.5772/intechopen.82572
42
Sarah Derks, Manon van Engeland. Epigenetic Therapy of Cancer2014; : 283 doi: 10.1007/978-3-642-38404-2_12
43
Mónica G. Mendoza-Rodríguez, C. Ángel Sánchez-Barrera, Blanca E. Callejas, Verónica García-Castillo, Diana L. Beristain-Terrazas, Norma L. Delgado-Buenrostro, Yolanda I. Chirino, Sonia A. León-Cabrera, Miriam Rodríguez-Sosa, Emma Bertha Gutierrez-Cirlos, Carlos Pérez-Plasencia, Felipe Vaca-Paniagua, Marco Antonio Meraz-Ríos, Luis I. Terrazas. Use of STAT6 Phosphorylation Inhibitor and Trimethylglycine as New Adjuvant Therapies for 5-Fluorouracil in Colitis-Associated TumorigenesisInternational Journal of Molecular Sciences 2020; 21(6): 2130 doi: 10.3390/ijms21062130
44
F. Crea, L. Fornaro, E. Paolicchi, G. Masi, P. Frumento, F. Loupakis, L. Salvatore, C. Cremolini, M. Schirripa, F. Graziano, M. Ronzoni, V. Ricci, W.L. Farrar, A. Falcone, R. Danesi. An EZH2 polymorphism is associated with clinical outcome in metastatic colorectal cancer patientsAnnals of Oncology 2012; 23(5): 1207 doi: 10.1093/annonc/mdr387
45
Ajay Goel, C. Richard Boland. Epigenetics of Colorectal CancerGastroenterology 2012; 143(6): 1442 doi: 10.1053/j.gastro.2012.09.032
46
Hiromu Suzuki, Eiichiro Yamamoto, Hiroshi Nakase, Tamotsu Sugai. DNA and Histone Methylation as Cancer TargetsCancer Drug Discovery and Development 2017; : 461 doi: 10.1007/978-3-319-59786-7_17
47
Zoe Veneti, Kalliopi Gkouskou, Aristides Eliopoulos. Polycomb Repressor Complex 2 in Genomic Instability and CancerInternational Journal of Molecular Sciences 2017; 18(8): 1657 doi: 10.3390/ijms18081657
48
Yanxin An, Yi Zhou, Gui Ren, Qifei Tian, Yuanyuan Lu, Hongtao Li, Kai Li, Tao Su, Bin Xu, Shuo Chen, Tao Wang, Xipeng Zhang, Yongzhan Nie, Xin Wang, Qingchuan Zhao. Elevated expression of MGb2-Ag/TRAK1 is correlated with poor prognosis in patients with colorectal cancerInternational Journal of Colorectal Disease 2011; 26(11): 1397 doi: 10.1007/s00384-011-1237-1
49
Lauren Krill, Wei Deng, Ramez Eskander, David Mutch, Susan Zweizig, Bang Hoang, Olga Ioffe, Leslie Randall, Heather Lankes, David S. Miller, Michael Birrer. Overexpression of enhance of Zeste homolog 2 (EZH2) in endometrial carcinoma: An NRG Oncology/Gynecologic Oncology Group StudyGynecologic Oncology 2020; 156(2): 423 doi: 10.1016/j.ygyno.2019.12.003
50
Francesco Crea, Lorenzo Fornaro, Guido Bocci, Lei Sun, William L. Farrar, Alfredo Falcone, Romano Danesi. EZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesisCancer and Metastasis Reviews 2012; 31(3-4): 753 doi: 10.1007/s10555-012-9387-3
51
James B Rawson, Bharati Bapat. Epigenetic biomarkers in colorectal cancer diagnosticsExpert Review of Molecular Diagnostics 2012; 12(5): 499 doi: 10.1586/erm.12.39
52
Evelyne Lima-Fernandes, Alex Murison, Tiago da Silva Medina, Yadong Wang, Anqi Ma, Cherry Leung, Genna M. Luciani, Jennifer Haynes, Aaron Pollett, Constanze Zeller, Shili Duan, Antonija Kreso, Dalia Barsyte-Lovejoy, Bradly G. Wouters, Jian Jin, Daniel D. De Carvalho, Mathieu Lupien, Cheryl H. Arrowsmith, Catherine A. O’Brien. Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cellsNature Communications 2019; 10(1) doi: 10.1038/s41467-019-09309-4
53
Sónia Carvalho, Micaela Freitas, Luís Antunes, Sara Monteiro-Reis, Marcia Vieira-Coimbra, Ana Tavares, Sofia Paulino, José Flávio Videira, Carmen Jerónimo, Rui Henrique. Prognostic value of histone marks H3K27me3 and H3K9me3 and modifying enzymes EZH2, SETDB1 and LSD-1 in colorectal cancerJournal of Cancer Research and Clinical Oncology 2018; 144(11): 2127 doi: 10.1007/s00432-018-2733-2
54
Szofia Hajósi-Kalcakosz, Eszter Vincze, Katalin Dezső, Sándor Paku, András Rókusz, Zoltán Sápi, Erika Tóth, Péter Nagy. EZH2 is a sensitive marker of malignancy in salivary gland tumorsDiagnostic Pathology 2015; 10(1) doi: 10.1186/s13000-015-0392-z
55
Jonathan R. Hart, Lujian Liao, John R. Yates, Peter K. Vogt. Essential role of Stat3 in PI3K-induced oncogenic transformationProceedings of the National Academy of Sciences 2011; 108(32): 13247 doi: 10.1073/pnas.1110486108
56
Hiroyoshi Kurihara, Reo Maruyama, Kazuya Ishiguro, Shinichi Kanno, Itaru Yamamoto, Keisuke Ishigami, Kei Mitsuhashi, Hisayoshi Igarashi, Miki Ito, Tokuma Tanuma, Yasutaka Sukawa, Kenji Okita, Tadashi Hasegawa, Kohzoh Imai, Hiroyuki Yamamoto, Yasuhisa Shinomura, Katsuhiko Nosho. The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathwayOncotarget 2016; 7(11): 12704 doi: 10.18632/oncotarget.7260
57
Bin Liu, Bo Pang, Qirui Wang, Shengji Yang, Taihong Gao, Qian Ding, Huajie Liu, Yihang Yang, Haitao Fan, Rui Zhang, Tao Xin, Guangming Xu, Qi Pang. EZH2 upregulation correlates with tumor invasiveness, proliferation, and angiogenesis in human pituitary adenomasHuman Pathology 2017; 66: 101 doi: 10.1016/j.humpath.2017.03.028
58
Carmen Salguero-Aranda, Daniel Sancho-Mensat, Beatriz Canals-Lorente, Sabena Sultan, Ajan Reginald, Lee Chapman, Sumitra Deb. STAT6 knockdown using multiple siRNA sequences inhibits proliferation and induces apoptosis of human colorectal and breast cancer cell linesPLOS ONE 2019; 14(5): e0207558 doi: 10.1371/journal.pone.0207558
59
Anne Benard, Inès J. Goossens-Beumer, Anneke Q. van Hoesel, Hamed Horati, Hein Putter, Eliane C. M. Zeestraten, Cornelis J. H. van de Velde, Peter J. K. Kuppen, Richard L. Eckert. Prognostic Value of Polycomb Proteins EZH2, BMI1 and SUZ12 and Histone Modification H3K27me3 in Colorectal CancerPLoS ONE 2014; 9(9): e108265 doi: 10.1371/journal.pone.0108265
60
Daisy PF Tsang, Alfred SL Cheng. Epigenetic regulation of signaling pathways in cancer: Role of the histone methyltransferase EZH2Journal of Gastroenterology and Hepatology 2011; 26(1): 19 doi: 10.1111/j.1440-1746.2010.06447.x
61
Bettina Fussbroich, Nina Wagener, Stephan Macher-Goeppinger, Axel Benner, Maria Fälth, Holger Sültmann, Angela Holzer, Karin Hoppe-Seyler, Felix Hoppe-Seyler, Moray Campbell. EZH2 Depletion Blocks the Proliferation of Colon Cancer CellsPLoS ONE 2011; 6(7): e21651 doi: 10.1371/journal.pone.0021651
62
Szofia Hajósi-Kalcakosz, Katalin Dezső, Edina Bugyik, Csaba Bödör, Sándor Paku, Zoltán Pávai, Judit Halász, Krisztina Schlachter, Zsuzsa Schaff, Péter Nagy. Enhancer of zeste homologue 2 (EZH2) is a reliable immunohistochemical marker to differentiate malignant and benign hepatic tumorsDiagnostic Pathology 2012; 7(1): 86 doi: 10.1186/1746-1596-7-86
63
Elizabeth G. Demicco, Paul W. Harms, Rajiv M. Patel, Steven C. Smith, Davis Ingram, Keila Torres, Shannon L. Carskadon, Sandra Camelo-Piragua, Jonathan B. McHugh, Javed Siddiqui, Nallasivam Palanisamy, David R. Lucas, Alexander J. Lazar, Wei-Lien Wang. Extensive Survey of STAT6 Expression in a Large Series of Mesenchymal TumorsAmerican Journal of Clinical Pathology 2015; 143(5): 672 doi: 10.1309/AJCPN25NJTOUNPNF