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For: Kann M, Schmitz A, Rabe B. Intracellular transport of hepatitis B virus. World J Gastroenterol 2007; 13(1): 39-47 [PMID: 17206753 DOI: 10.3748/wjg.v13.i1.39]
URL: https://www.wjgnet.com/1007-9327/full/v13/i1/39.htm
Number Citing Articles
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Dawei Cai, Courtney Mills, Wenquan Yu, Ran Yan, Carol E. Aldrich, Jeffry R. Saputelli, William S. Mason, Xiaodong Xu, Ju-Tao Guo, Timothy M. Block, Andrea Cuconati, Haitao Guo. Identification of Disubstituted Sulfonamide Compounds as Specific Inhibitors of Hepatitis B Virus Covalently Closed Circular DNA Formation. Antimicrobial Agents and Chemotherapy 2012; 56(8) doi: 10.1128/AAC.00473-12
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Chao Chen, Joseph Che-Yen Wang, Elizabeth E. Pierson, David Z. Keifer, Mildred Delaleau, Lara Gallucci, Christian Cazenave, Michael Kann, Martin F. Jarrold, Adam Zlotnick, Jianming Hu. Importin β Can Bind Hepatitis B Virus Core Protein and Empty Core-Like Particles and Induce Structural Changes. PLOS Pathogens 2016; 12(8) doi: 10.1371/journal.ppat.1005802
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Hye Won Lee, Jae Seung Lee, Sang Hoon Ahn. Hepatitis B Virus Cure: Targets and Future Therapies. International Journal of Molecular Sciences 2020; 22(1) doi: 10.3390/ijms22010213
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Justin W. Flatt, Urs F. Greber. Viral mechanisms for docking and delivering at nuclear pore complexes. Seminars in Cell & Developmental Biology 2017; 68 doi: 10.1016/j.semcdb.2017.05.008
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Xiuji Cui, Laurie Ludgate, Xiaojun Ning, Jianming Hu. Maturation-Associated Destabilization of Hepatitis B Virus Nucleocapsid. Journal of Virology 2013; 87(21) doi: 10.1128/JVI.01912-13
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Michael Nassal. Hepatitis B viruses: Reverse transcription a different way. Virus Research 2008; 134(1-2) doi: 10.1016/j.virusres.2007.12.024
14
Jehoon Kim, Jianzhong Wu. A Theoretical Study of SRPK Interaction with the Flexible Domains of Hepatitis B Capsids. Biophysical Journal 2014; 107(6) doi: 10.1016/j.bpj.2014.07.032
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Dai Kurihara, Hidetaka Akita, Asako Kudo, Tomoya Masuda, Shiroh Futaki, Hideyoshi Harashima. Effect of Polyethyleneglycol Spacer on the Binding Properties of Nuclear Localization Signal-Modified Liposomes to Isolated Nucleus. Biological and Pharmaceutical Bulletin 2009; 32(7) doi: 10.1248/bpb.32.1303
18
Lei Wei, Alexander Ploss. Mechanism of Hepatitis B Virus cccDNA Formation. Viruses 2021; 13(8) doi: 10.3390/v13081463
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Balasubramanian Venkatakrishnan, Adam Zlotnick. The Structural Biology of Hepatitis B Virus: Form and Function. Annual Review of Virology 2016; 3(1) doi: 10.1146/annurev-virology-110615-042238
21
Gang Wang, Jun Guan, Nazif U. Khan, Guojun Li, Junwei Shao, Qihui Zhou, Lichen Xu, Chunhong Huang, Jingwen Deng, Haihong Zhu, Zhi Chen. Potential capacity of interferon-α to eliminate covalently closed circular DNA (cccDNA) in hepatocytes infected with hepatitis B virus. Gut Pathogens 2021; 13(1) doi: 10.1186/s13099-021-00421-9
22
Sheikh Mohammad Fazle Akbar, Mamun Al Mahtab, Osamu Yoshida, Yoichi Hiasa. Cellular and Molecular Mechanisms Underlying Scope and Limitation of Ongoing and Innovative Therapies for Treating Chronic Hepatitis B. Livers 2022; 2(1) doi: 10.3390/livers2010001
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Gang Wang, Zhi Chen, Jian Wu. HBV Genomic Integration and Hepatocellular Carcinoma. Advanced Gut & Microbiome Research 2022; 2022 doi: 10.1155/2022/2140886
26
Christine Kim, Lauren F. Barnes, Christopher J. Schlicksup, Angela J. Patterson, Brian Bothner, Martin F. Jarrold, Che-Yen Joseph Wang, Adam Zlotnick, J.-H. James Ou. Core Protein-Directed Antivirals and Importin β Can Synergistically Disrupt Hepatitis B Virus Capsids. Journal of Virology 2022; 96(2) doi: 10.1128/JVI.01395-21
27
Samuel Hofmann, Verena Plank, Peter Groitl, Nathalie Skvorc, Katharina Hofmann, Julius Luther, Chunkyu Ko, Peter Zimmerman, Volker Bruss, Daniela Stadler, Arnaud Carpentier, Shahinda Rezk, Michael Nassal, Ulrike Protzer, Sabrina Schreiner, Peter Pelka. SUMO Modification of Hepatitis B Virus Core Mediates Nuclear Entry, Promyelocytic Leukemia Nuclear Body Association, and Efficient Formation of Covalently Closed Circular DNA. Microbiology Spectrum 2023; 11(3) doi: 10.1128/spectrum.00446-23
28
Dong-li Li, Wen-lin Wu, Hai-peng Liu. CqProfilin enhances WSSV infection by promoting viral intracellular transport through binding to both viral nucleocapsid and actin cytoskeleton. Developmental & Comparative Immunology 2025; 162 doi: 10.1016/j.dci.2024.105281
29
Laura J. Lester, Suneal K. Agarwal. Sexually Transmitted Infections and Sexually Transmitted Diseases. 2011;  doi: 10.1007/978-3-642-14663-3_42
30
Haitao Guo, Dong Jiang, Tianlun Zhou, Andrea Cuconati, Timothy M. Block, Ju-Tao Guo. Characterization of the Intracellular Deproteinized Relaxed Circular DNA of Hepatitis B Virus: an Intermediate of Covalently Closed Circular DNA Formation. Journal of Virology 2007; 81(22) doi: 10.1128/JVI.01123-07
31
Tarik Asselah, Dimitri Loureiro, Nathalie Boyer, Abdellah Mansouri. Targets and future direct-acting antiviral approaches to achieve hepatitis B virus cure. The Lancet Gastroenterology & Hepatology 2019; 4(11) doi: 10.1016/S2468-1253(19)30190-6
32
Abdullah Ely, Prashika Singh, Tiffany S. Smith, Patrick Arbuthnot. In vitro transcribed mRNA for expression of designer nucleases: Advantages as a novel therapeutic for the management of chronic HBV infection. Advanced Drug Delivery Reviews 2021; 168 doi: 10.1016/j.addr.2020.05.010
33
Stephan Urban, Andreas Schulze, Maura Dandri, Joerg Petersen. The replication cycle of hepatitis B virus. Journal of Hepatology 2010; 52(2) doi: 10.1016/j.jhep.2009.10.031
34
Andrea Caballero, David Tabernero, Maria Buti, Francisco Rodriguez-Frias. Hepatitis B virus: The challenge of an ancient virus with multiple faces and a remarkable replication strategy. Antiviral Research 2018; 158 doi: 10.1016/j.antiviral.2018.07.019
35
Michael Nassal, Immanuel Leifer, Ida Wingert, Kai Dallmeier, Simone Prinz, Jolanta Vorreiter. A Structural Model for Duck Hepatitis B Virus Core Protein Derived by Extensive Mutagenesis. Journal of Virology 2007; 81(23) doi: 10.1128/JVI.00846-07
36
Nikta Fay, Nelly Panté. Nuclear entry of DNA viruses. Frontiers in Microbiology 2015; 6 doi: 10.3389/fmicb.2015.00467
37
Nuruddin Unchwaniwala, Nathan M. Sherer, Daniel D. Loeb, R. M. Sandri-Goldin. Hepatitis B Virus Polymerase Localizes to the Mitochondria, and Its Terminal Protein Domain Contains the Mitochondrial Targeting Signal. Journal of Virology 2016; 90(19) doi: 10.1128/JVI.01229-16
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Christine Kim, Christopher J. Schlicksup, Carolina Pérez-Segura, Jodi A. Hadden-Perilla, Joseph Che-Yen Wang, Adam Zlotnick. Structure of the Hepatitis B virus capsid quasi-6-fold with a trapped C-terminal domain reveals capsid movements associated with domain exit. Journal of Biological Chemistry 2023; 299(9) doi: 10.1016/j.jbc.2023.105104
40
Mary S. Dhason, Joseph C.-Y. Wang, Michael F. Hagan, Adam Zlotnick. Differential assembly of Hepatitis B Virus core protein on single- and double-stranded nucleic acid suggest the dsDNA-filled core is spring-loaded. Virology 2012; 430(1) doi: 10.1016/j.virol.2012.04.012
41
Valentina Sirri, Silvio Urcuqui-Inchima, Pascal Roussel, Danièle Hernandez-Verdun. Nucleolus: the fascinating nuclear body. Histochemistry and Cell Biology 2008; 129(1) doi: 10.1007/s00418-007-0359-6
42
Cong Li, Yixue Wang, Rui Xiong, Qiaoyi Li, Zhongmin Zhou, Qingmei Liu, Yonghe Qi, Zihao Gao, Guangwei Xu, Linqiang Fang, Yinyan Sun, Michael Farzan, Hyeryun Choe, Jianhua Sui, Wenhui Li. Scavenger receptor class F member 2 is an intracellular receptor for hepatitis B virus. Cell 2026; 189(14) doi: 10.1016/j.cell.2026.04.045
43
Zhongchao Zhao, Joseph Che-Yen Wang, Giovanni Gonzalez-Gutierrez, Balasubramanian Venkatakrishnan, Roi Asor, Daniel Khaykelson, Uri Raviv, Adam Zlotnick, J.-H. James Ou. Structural Differences between the Woodchuck Hepatitis Virus Core Protein in the Dimer and Capsid States Are Consistent with Entropic and Conformational Regulation of Assembly. Journal of Virology 2019; 93(14) doi: 10.1128/JVI.00141-19
44
Peter Vanlandschoot, Catelijne Stortelers, Els Beirnaert, Lorena Itatí Ibañez, Bert Schepens, Erik Depla, Xavier Saelens. Nanobodies®: New ammunition to battle viruses. Antiviral Research 2011; 92(3) doi: 10.1016/j.antiviral.2011.09.002
45
Jiradej Makjaroen, Poorichaya Somparn, Kenneth Hodge, Witthaya Poomipak, Nattiya Hirankarn, Trairak Pisitkun. Comprehensive Proteomics Identification of IFN-λ3-regulated Antiviral Proteins in HBV-transfected Cells. Molecular & Cellular Proteomics 2018; 17(11) doi: 10.1074/mcp.RA118.000735
46
Wen Siang Tan, Kok Lian Ho. Phage display creates innovative applications to combat hepatitis B virus. World Journal of Gastroenterology 2014; 20(33): 11650-11670 doi: 10.3748/wjg.v20.i33.11650
47
Hung-Chih Yang, Shiou-Hwei Yeh, Pei-Jer Chen, Ding-Shinn Chen. Viruses and Human Cancer. 2014;  doi: 10.1007/978-1-4939-0870-7_6
48
José L. Neira. Structure and Physics of Viruses. Subcellular Biochemistry 2024; 105 doi: 10.1007/978-3-031-65187-8_6
49
50
51
K. Weigand, A. Knaust, H. Schaller. Assembly and export determine the intracellular distribution of hepatitis B virus core protein subunits. Journal of General Virology 2010; 91(1) doi: 10.1099/vir.0.013698-0
52
Wataru Kinoshita, Naoki Ogura, Koichi Watashi, Takaji Wakita. Host factor PRPF31 is involved in cccDNA production in HBV-replicating cells. Biochemical and Biophysical Research Communications 2017; 482(4) doi: 10.1016/j.bbrc.2016.11.085
53
54
P. Pumpens, E. Grens. The true story and advantages of the famous Hepatitis B virus core particles: Outlook 2016. Molecular Biology 2016; 50(4) doi: 10.1134/S0026893316040099
55
Christopher John Schlicksup, Joseph Che-Yen Wang, Samson Francis, Balasubramanian Venkatakrishnan, William W Turner, Michael VanNieuwenhze, Adam Zlotnick. Hepatitis B virus core protein allosteric modulators can distort and disrupt intact capsids. eLife 2018; 7 doi: 10.7554/eLife.31473
56
Timothy M. Block, Haitao Guo, Ju-Tao Guo. Molecular Virology of Hepatitis B Virus for Clinicians. Clinics in Liver Disease 2007; 11(4) doi: 10.1016/j.cld.2007.08.002
57
Dejuan Sun, Lingjuan Zhu, Dahong Yao, Lixia Chen, Leilei Fu, Liang Ouyang. Recent progress in potential anti-hepatitis B virus agents: Structural and pharmacological perspectives. European Journal of Medicinal Chemistry 2018; 147 doi: 10.1016/j.ejmech.2018.02.001
58
Josef Köck, Christine Rösler, Jing-Jing Zhang, Hubert E. Blum, Michael Nassal, Christian Thoma, Jing-hsiung James Ou. Generation of Covalently Closed Circular DNA of Hepatitis B Viruses via Intracellular Recycling Is Regulated in a Virus Specific Manner. PLoS Pathogens 2010; 6(9) doi: 10.1371/journal.ppat.1001082
59
Haitao Guo, Richeng Mao, Timothy M. Block, Ju-Tao Guo. Production and Function of the Cytoplasmic Deproteinized Relaxed Circular DNA of Hepadnaviruses. Journal of Virology 2010; 84(1) doi: 10.1128/JVI.01921-09
60
Thabani Sibiya, Lunga Xaba, Lulama Mthethwa, Anil A. Chuturgoon, Nokukhanya Msomi. The Evolution of Cell Culture Systems to Study Hepatitis B Virus Pathogenesis and Antiviral Susceptibility. Viruses 2025; 17(8) doi: 10.3390/v17081057
61
Jieliang Chen, Min Wu, Kuancheng Liu, Wen Zhang, Yaming Li, Xiaohui Zhou, Lu Bai, Zhenghong Yuan. New insights into hepatitis B virus biology and implications for novel antiviral strategies. National Science Review 2015; 2(3) doi: 10.1093/nsr/nwv044
62
Christopher John Schlicksup, Patrick Laughlin, Steven Dunkelbarger, Joseph Che-Yen Wang, Adam Zlotnick. Local Stabilization of Subunit–Subunit Contacts Causes Global Destabilization of Hepatitis B Virus Capsids. ACS Chemical Biology 2020; 15(6) doi: 10.1021/acschembio.0c00320
63
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65
Barbara Schroeder, Mark McNiven. The Liver. 2009;  doi: 10.1002/9780470747919.ch7
66
Dong Meng, Rex P Hjelm, Jianming Hu, Jianzhong Wu. A Theoretical Model for the Dynamic Structure of Hepatitis B Nucleocapsid. Biophysical Journal 2011; 101(10) doi: 10.1016/j.bpj.2011.10.002
67
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Fabien Abdul, Bénédicte Ndeboko, Thierry Buronfosse, Fabien Zoulim, Michael Kann, Peter E. Nielsen, Lucyna Cova, Wang-Shick Ryu. Potent Inhibition of Late Stages of Hepadnavirus Replication by a Modified Cell Penetrating Peptide. PLoS ONE 2012; 7(11) doi: 10.1371/journal.pone.0048721
70
71
Gaëtan Ligat, Eloi R Verrier, Michael Nassal, Thomas F Baumert. Hepatitis B virus–host interactions and novel targets for viral cure. Current Opinion in Virology 2021; 49 doi: 10.1016/j.coviro.2021.04.009
72
Lena Allweiss, Maura Dandri. The Role of cccDNA in HBV Maintenance. Viruses 2017; 9(6) doi: 10.3390/v9060156
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74
Katrin Busch, Robert Thimme. Natural history of chronic hepatitis B virus infection. Medical Microbiology and Immunology 2015; 204(1) doi: 10.1007/s00430-014-0369-7
75
Ahmed Diab, Adrien Foca, Fabien Zoulim, David Durantel, Ourania Andrisani. The diverse functions of the hepatitis B core/capsid protein (HBc) in the viral life cycle: Implications for the development of HBc-targeting antivirals. Antiviral Research 2018; 149 doi: 10.1016/j.antiviral.2017.11.015
76
Martin F. Jarrold. Applications of Charge Detection Mass Spectrometry in Molecular Biology and Biotechnology. Chemical Reviews 2022; 122(8) doi: 10.1021/acs.chemrev.1c00377
77
Daniel Puntener, Urs F. Greber. DNA-tumor virus entry—From plasma membrane to the nucleus. Seminars in Cell & Developmental Biology 2009; 20(5) doi: 10.1016/j.semcdb.2009.03.014
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B. Serruys, F. Van Houtte, A. Farhoudi-Moghadam, G. Leroux-Roels, P. Vanlandschoot. Production, characterization and in vitro testing of HBcAg-specific VHH intrabodies. Journal of General Virology 2010; 91(3) doi: 10.1099/vir.0.016063-0
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Camille Sureau. Hepatitis B Virus in Human Diseases. Molecular and Translational Medicine 2016;  doi: 10.1007/978-3-319-22330-8_7
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Kai Dallmeier, Michael Nassal. Comparative Hepatitis. 2008;  doi: 10.1007/978-3-7643-8558-3_14
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Jasmine Samal, Manish Kandpal, Perumal Vivekanandan. Molecular Mechanisms Underlying Occult Hepatitis B Virus Infection. Clinical Microbiology Reviews 2012; 25(1) doi: 10.1128/CMR.00018-11
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Xian Hao, Xin Shang, Jiazhen Wu, Yuping Shan, Mingjun Cai, Junguang Jiang, Zhong Huang, Zhiyong Tang, Hongda Wang. Single‐Particle Tracking of Hepatitis B Virus‐like Vesicle Entry into Cells. Small 2011; 7(9) doi: 10.1002/smll.201002020
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Christian Königer, Ida Wingert, Moritz Marsmann, Christine Rösler, Jürgen Beck, Michael Nassal. Involvement of the host DNA-repair enzyme TDP2 in formation of the covalently closed circular DNA persistence reservoir of hepatitis B viruses. Proceedings of the National Academy of Sciences 2014; 111(40) doi: 10.1073/pnas.1409986111
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William S. Mason, Sam Litwin, Allison R. Jilbert. Immune selection during chronic hepadnavirus infection. Hepatology International 2008; 2(1) doi: 10.1007/s12072-007-9024-3
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He-ming Sun, Xing-yu Wang, Hong-qin Xu, Yan-hang Gao. Navigating the Viral Hepatitis Drug Landscape: New Discoveries and Enduring Challenges. A Narrative Review. Infectious Diseases and Therapy 2026; 15(4) doi: 10.1007/s40121-026-01321-8
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Yilin Li, Yishuang Sun, Fuyun Sun, Rong Hua, Chenlin Li, Lang Chen, Deyin Guo, Jingfang Mu. Mechanisms and Effects on HBV Replication of the Interaction between HBV Core Protein and Cellular Filamin B. Virologica Sinica 2018; 33(2) doi: 10.1007/s12250-018-0023-4
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Bo Liu, Xin Wen, Canhua Huang, Yuquan Wei. Unraveling the complexity of hepatitis B virus: From molecular understanding to therapeutic strategy in 50 years. The International Journal of Biochemistry & Cell Biology 2013; 45(9) doi: 10.1016/j.biocel.2013.06.017
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Angela Patterson, Zhongchao Zhao, Elizabeth Waymire, Adam Zlotnick, Brian Bothner. Dynamics of Hepatitis B Virus Capsid Protein Dimer Regulate Assembly through an Allosteric Network. ACS Chemical Biology 2020; 15(8) doi: 10.1021/acschembio.0c00481
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Michael Nassal. New Insights into Hbv Replication: New Opportunities for Improved Therapies. Future Virology 2009; 4(1) doi: 10.2217/17460794.4.1.55
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Adam Zlotnick, Balasubramanian Venkatakrishnan, Zhenning Tan, Eric Lewellyn, William Turner, Samson Francis. Core protein: A pleiotropic keystone in the HBV lifecycle. Antiviral Research 2015; 121 doi: 10.1016/j.antiviral.2015.06.020
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Zahra Zahid Piracha, Hyeonjoong Kwon, Umar Saeed, Jumi Kim, Jaesung Jung, Yong-Joon Chwae, Sun Park, Ho-Joon Shin, Kyongmin Kim, J.-H. James Ou. RETRACTED: Sirtuin 2 Isoform 1 Enhances Hepatitis B Virus RNA Transcription and DNA Synthesis through the AKT/GSK-3β/β-Catenin Signaling Pathway. Journal of Virology 2018; 92(21) doi: 10.1128/jvi.00955-18
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Sarah Cohen, Shelly Au, Nelly Panté. How viruses access the nucleus. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2011; 1813(9) doi: 10.1016/j.bbamcr.2010.12.009
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Hong Tang, Mei-Fang Han, Ji-Ming Zhang. Acute Exacerbation of Chronic Hepatitis B. 2019;  doi: 10.1007/978-94-024-1606-0_3
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Jehoon Kim, Jianzhong Wu. Self‐Assembling Systems. 2016;  doi: 10.1002/9781119113171.ch6
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Raimundas Razanskas, Kestutis Sasnauskas. Interaction of hepatitis B virus core protein with human GIPC1. Archives of Virology 2010; 155(2) doi: 10.1007/s00705-009-0561-z
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Qiao He, Wanyu Li, Jihua Ren, Yecai Huang, Ying Huang, Qin Hu, Juan Chen, Weixian Chen. ZEB2 inhibits HBV transcription and replication by targeting its core promoter. Oncotarget 2016; 7(13) doi: 10.18632/oncotarget.7435
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Alexandra Alexopoulou, Larisa Vasilieva, Peter Karayiannis. New Approaches to the Treatment of Chronic Hepatitis B. Journal of Clinical Medicine 2020; 9(10) doi: 10.3390/jcm9103187
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Joao M. Serigado, Manhal Izzy, Harmit Kalia. Novel therapies and potential therapeutic targets in the management of chronic hepatitis B. European Journal of Gastroenterology & Hepatology 2017; 29(9) doi: 10.1097/MEG.0000000000000911
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Hua Yang, Jiayin Mo, Qi Xiang, Peiyi Zhao, Yunting Song, Ge Yang, Kailang Wu, Yingle Liu, Weiyong Liu, Jianguo Wu. SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation. Viruses 2020; 12(3) doi: 10.3390/v12030273