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For: Thong-Ngam D, Tangkijvanich P, Lerknimitr R, Mahachai V, Theamboonlers A, Poovorawan Y. Diagnostic role of serum interleukin-18 in gastric cancer patients. World J Gastroenterol 2006; 12(28): 4473-4477 [PMID: 16874857 DOI: 10.3748/wjg.v12.i28.4473]
URL: https://www.wjgnet.com/1007-9327/full/v12/i28/4473.htm
Number Citing Articles
1
Zhanlong Shen, Hanna Seppänen, Sanna Vainionpää, Yingjiang Ye, Shan Wang, Harri Mustonen, Pauli Puolakkainen. IL10, IL11, IL18 are differently expressed in CD14+ TAMs and play different role in regulating the invasion of gastric cancer cells under hypoxia. Cytokine 2012; 59(2) doi: 10.1016/j.cyto.2012.04.033
2
Faruk Tas, Ceren Tilgen Yasasever, Senem Karabulut, Didem Tastekin, Derya Duranyildiz. Clinical significance of serum interleukin-18 (IL-18) levels in patients with gastric cancer. Biomedicine & Pharmacotherapy 2015; 70 doi: 10.1016/j.biopha.2014.12.040
3
Hui Yan, Penggao Wang, Qiang Zhou, Xiangyang Dong, Qionglin Wang, Ziqiao Yuan, Bo Zhai, Yang Zhou. Eupafolin hinders cross-talk between gastric cancer cells and cancer-associated fibroblasts by abrogating the IL18/IL18RAP signaling axis. Phytomedicine 2024; 134 doi: 10.1016/j.phymed.2024.155984
4
Tao Wu, Lingna Zhang, Jiao Tian, Yuyuan Lu, Yan Yang, Xin Yang, Penghui Jin, Yuanhui Gu, Xiaoke Wang, Lin Yi. Correlation between dyslipidaemia and gastric cancer: pathogenesis to prevention and treatment strategies. Lipids in Health and Disease 2025; 24(1) doi: 10.1186/s12944-025-02625-3
5
Wei-Chih Liao, Jaw-Town Lin, Chun-Ying Wu, Shih-Pei Huang, Ming-Tsan Lin, Ariel Sing-Huei Wu, Yu-Jie Huang, Ming-Shiang Wu. Serum Interleukin-6 Level but not Genotype Predicts Survival after Resection in Stages II and III Gastric Carcinoma. Clinical Cancer Research 2008; 14(2) doi: 10.1158/1078-0432.CCR-07-1032
6
Arseniy E. Yuzhalin, Anton G. Kutikhin. Interleukins in Cancer Biology. 2015;  doi: 10.1016/B978-0-12-801121-8.00002-6
7
Jeroen Kool, Léon Reubsaet, Feikje Wesseldijk, Raquel T. Maravilha, Martijn W. Pinkse, Clive S. D'Santos, Jacobus J. van Hilten, Freek J. Zijlstra, Albert J. R. Heck. Suction blister fluid as potential body fluid for biomarker proteins. PROTEOMICS 2007; 7(20) doi: 10.1002/pmic.200600938
8
琳 翁. Interstitial Disease of Autosomal Dominant Polycystic Kidney Disease. Journal of Physiology Studies 2014; 2(02) doi: 10.12677/JPS.2014.22002
9
Eiichi Tahara. Abnormal Growth Factor/Cytokine Network in Gastric Cancer. Cancer Microenvironment 2008; 1(1) doi: 10.1007/s12307-008-0008-1
10
Duangporn Werawatganon, Sittikorn Linlawan, Kessarin Thanapirom, Kanjana Somanawat, Naruemon Klaikeaw, Rungsun Rerknimitr, Prasong Siriviriyakul. Aloe vera attenuated liver injury in mice with acetaminophen-induced hepatitis. BMC Complementary and Alternative Medicine 2014; 14(1) doi: 10.1186/1472-6882-14-229
11
Pinghu Sun, Qiwen Ben, Shuiping Tu, Wenjie Dong, Xiaoguang Qi, Yunlin Wu. Serum Interleukin-33 Levels in Patients with Gastric Cancer. Digestive Diseases and Sciences 2011; 56(12) doi: 10.1007/s10620-011-1760-5
12
ZHANLONG SHEN, YINGJIANG YE, TUULI KAUTTU, HANNA SEPPÄNEN, SANNA VAINIONPÄÄ, SHAN WANG, HARRI MUSTONEN, PAULI PUOLAKKAINEN. The novel focal adhesion gene kindlin-2 promotes the invasion of gastric cancer cells mediated by tumor-associated macrophages. Oncology Reports 2013; 29(2) doi: 10.3892/or.2012.2137
13
Yunguang Liu, Na Lin, Li Huang, Qunqing Xu, Guangfu Pang. Genetic Polymorphisms of the Interleukin-18 Gene and Risk of Prostate Cancer. DNA and Cell Biology 2007; 26(8) doi: 10.1089/dna.2007.0600
14
Xin Yang, Man-Tang Qiu, Jing-Wen Hu, Feng Jiang, Ming Li, Jie Wang, Qin Zhang, Rong Yin, Lin Xu, Roger Chammas. Association of Interleukin-18 Gene Promoter −607 C>A and −137G>C Polymorphisms with Cancer Risk: A Meta-Analysis of 26 Studies. PLoS ONE 2013; 8(9) doi: 10.1371/journal.pone.0073671
15
Lancelot Lobo, M. James Rohith, Suchetha Kumari N., Kishan Prasad H. L.. Utility of serum interleukin-18 (IL-18) as a tumour marker in gastric cancer. Biomedicine 2022; 42(5) doi: 10.51248/.v42i5.1442
16
17
Do-Kyong Kim, Sung Yong Oh, Hyuk-Chan Kwon, Suee Lee, Kyung A Kwon, Byung Geun Kim, Seong-Geun Kim, Sung-Hyun Kim, Jin Seok Jang, Min Chan Kim, Kyeong Hee Kim, Jin-Yeong Han, Hyo-Jin Kim. Clinical significances of preoperative serum interleukin-6 and C-reactive protein level in operable gastric cancer. BMC Cancer 2009; 9(1) doi: 10.1186/1471-2407-9-155
18
Tahseen H. Nasti, Laura Timares. Inflammasome Activation of IL‐1 Family Mediators in Response to Cutaneous Photodamage†. Photochemistry and Photobiology 2012; 88(5) doi: 10.1111/j.1751-1097.2012.01182.x
19
Kyung A Kwon, Sung Hyun Kim, Sung Yong Oh, Suee Lee, Jin-Yeong Han, Kyeong Hee Kim, Ri Young Goh, Hong Jo Choi, Ki Jae Park, Mee Sook Roh, Hyo-Jin Kim, Hyuk-Chan Kwon, Jong Hoon Lee. Clinical significance of preoperative serum vascular endothelial growth factor, interleukin-6, and C-reactive protein level in colorectal cancer. BMC Cancer 2010; 10(1) doi: 10.1186/1471-2407-10-203
20
Praveen Ravishankaran, R Karunanithi. Clinical significance of preoperative serum interleukin-6 and C-reactive protein level in breast cancer patients. World Journal of Surgical Oncology 2011; 9(1) doi: 10.1186/1477-7819-9-18
21
Joan A. Loayza-Castro, Luisa E.M. Vásquez-Romero, Lupita A.M. Valladolid-Sandoval, Enrique Vigil-Ventura, Nataly M. Sanchez-Tamay, Fiorella E. Zuzunaga-Montoya, Rafael Tapia-Limonchi, Víctor J. Vera-Ponce. Interleukin-6 as a Risk and Prognostic Biomarker in Gastric Cancer: A Systematic Review and Meta-Analysis. Journal of Cancer Research Updates 2024; 13 doi: 10.30683/1929-2279.2024.13.07
22
Brendan J. Jenkins, Virginie Deswaerte. Inflammation and Cancer. Methods in Molecular Biology 2018; 1725 doi: 10.1007/978-1-4939-7568-6_18
23
Liping Wang, Baoxin Zheng, Liqun Jia, Aihua Liang. Inflammatory storms of gastric cancer progression and anti-inflammatory intervention. Chinese Herbal Medicines 2026;  doi: 10.1016/j.chmed.2026.08.001
24
Natalia Siwińska, Agnieszka Żak-Bochenek, Hannah Trodd, Zuzanna Czekaj, Ewa Kumiega, Artur Niedźwiedź, Michael Hewetson. Effects of omeprazole therapy administered via different routes on urinary parameters and selected interleukins in horses with equine gastric ulcer syndrome. Journal of Equine Veterinary Science 2026; 167 doi: 10.1016/j.jevs.2026.106127
25
Anjali Shinde, Xiaoyun Tang, Rajesh Singh, David N. Brindley. Infliximab, a Monoclonal Antibody against TNF-α, Inhibits NF-κB Activation, Autotaxin Expression and Breast Cancer Metastasis to Lungs. Cancers 2023; 16(1) doi: 10.3390/cancers16010052
26
Ming Wang, Xiao-Yang Zhu, Liang Wang, Yu Lin, Qing-Yi Wei. The -607C/A Polymorphisms in Interleukin-18 Gene Promoter Contributes to Cancer Risk: Evidence from A Meta-Analysis of 22 Case-Control Studies. PLoS ONE 2013; 8(10) doi: 10.1371/journal.pone.0076915
27
N.I. Mikulyak, A.S. Kinzirsky, O.A. Yurtaev, D.I. Zhuravlev. Study of serum cytokine concentration in primary patients with gastric cancer. P.A. Herzen Journal of Oncology 2025; 14(2) doi: 10.17116/onkolog20251402125
28
Shafiq Ur Rehman, Mahd Rauf, Zaigham Abbas, Muhammed Haroon Hamed, Ishtiaq Qadri. Role of Some Predominant Host Immunomodulators' Single Nucleotide Polymorphisms in Severity of Hepatitis B Virus and Hepatitis C Virus Infection. Viral Immunology 2016; 29(10) doi: 10.1089/vim.2016.0062
29
Fatemeh Babajani, Hadi Mozafari. Integrated Network Analysis Suggests an miR‐21/MMP/VEGF‐Associated Regulatory Axis in Gastric Cancer. Cancer Reports 2026; 9(8) doi: 10.1002/cnr2.70634
30
Mohammad Reza Haghshenas, Seyed Vahid Hosseini, Mahmoud Mahmoudi, Mehdi Saberi‐Firozi, Shirin Farjadian, Abbas Ghaderi. IL‐18 serum level and IL‐18 promoter gene polymorphism in Iranian patients with gastrointestinal cancers. Journal of Gastroenterology and Hepatology 2009; 24(6) doi: 10.1111/j.1440-1746.2009.05791.x
31
Marta Łukaszewicz-Zając, Maciej Szmitkowski, Ala Litman-Zawadzka, Barbara Mroczko. Matrix Metalloproteinases and Their Tissue Inhibitors in Comparison to Other Inflammatory Proteins in Gastric Cancer (GC). Cancer Investigation 2016; 34(7) doi: 10.1080/07357907.2016.1197237
32
Marta Łukaszewicz-Zając, Barbara Mroczko, Mariusz Gryko, Bogusław Kędra, Maciej Szmitkowski. Comparison between clinical significance of serum proinflammatory proteins (IL-6 and CRP) and classic tumor markers (CEA and CA 19-9) in gastric cancer. Clinical and Experimental Medicine 2011; 11(2) doi: 10.1007/s10238-010-0114-5
33
Behrooz Mozaffari Namin, Mohammad Mehdi Soltan Dallal, Nasser Ebrahimi Daryani. The Effect of Campylobacter concisus on Expression of IL-18, TNF-α and p53 in Barrett’s Cell Lines. Jundishapur Journal of Microbiology 2015; 8(12) doi: 10.5812/jjm.26393
34
Chintana Chirathaworn, Yong Poovorawan. Targeted Cancer Immune Therapy. 2009;  doi: 10.1007/978-1-4419-0170-5_2
35
Chen Hong-Ying, Cui Bao-An, Xia Ping-An, Li Xin-Sheng, Yang Ming-Fan, Zheng Lan-Lan. Cloning and expression of Ma duck interleukin-18 mature protein gene and biological activity detection. Chinese Journal of Agricultural Biotechnology 2007; 4(3) doi: 10.1017/S1479236207001842
36
XIAO-LEI YE, YA-RONG ZHAO, GUO-BIN WENG, YI-CHEN CHEN, XUE-NI WEI, JING-PING SHAO, HUI JI. IL-33-induced JNK pathway activation confers gastric cancer chemotherapy resistance. Oncology Reports 2015; 33(6) doi: 10.3892/or.2015.3898
37
Aunchalee Jaroenlapnopparat, Khushboo Bhatia, Sahin Coban. Inflammation and Gastric Cancer. Diseases 2022; 10(3) doi: 10.3390/diseases10030035
38
Jun Yu, Yanhong Jia, Kin Fai Cheung, Zhirong Zeng, Linwei Tian, Shiyan Wang, Pinjin Hu, Joseph J. Y. Sung. Polymorphisms inInterleukin-6-6331 Influences the Susceptibility of a Chinese Population to Gastric Cancer. Cancer Investigation 2011; 29(8) doi: 10.3109/07357907.2011.605411
39
Ye-Sheng Wei, Yan Lan, Yun-Guang Liu, Hui Tang, Ren-Guang Tang, Jian-Chu Wang. Interleukin-18 gene promoter polymorphisms and the risk of esophageal squamous cell carcinoma. Acta Oncologica 2007; 46(8) doi: 10.1080/02841860701373595
40
Virginie Deswaerte, Paul Nguyen, Alison West, Alison F. Browning, Liang Yu, Saleela M. Ruwanpura, Jesse Balic, Thaleia Livis, Charlotte Girard, Adele Preaudet, Hiroko Oshima, Ka Yee Fung, Hazel Tye, Meri Najdovska, Matthias Ernst, Masanobu Oshima, Cem Gabay, Tracy Putoczki, Brendan J. Jenkins. Inflammasome Adaptor ASC Suppresses Apoptosis of Gastric Cancer Cells by an IL18-Mediated Inflammation-Independent Mechanism. Cancer Research 2018; 78(5) doi: 10.1158/0008-5472.CAN-17-1887
41
Marcus Vinicius Cândido, Pernillä Syrjä, Mohsen Hanifeh, Jaan Lepajõe, Kati Salla, Susanne Kilpinen, Peter-John Mäntylä Noble, Thomas Spillmann. Gastric mucosal pathology in Belgian Shepherd dogs with and without clinical signs of gastric disease. Acta Veterinaria Scandinavica 2021; 63(1) doi: 10.1186/s13028-021-00570-6
42
Shaojun Nong, Yueping Zhang, Shujun Zhou, Wenguang Li, Limin Ma, You Wu. Relationship between serum IL-18 and VEGF levels in patients with prostate cancer. The Chinese-German Journal of Clinical Oncology 2010; 9(11) doi: 10.1007/s10330-010-0702-6
43
YEFENG YIN, XIULIAN SI, YAN GAO, LEI GAO, JIANGNING WANG. The nuclear factor-κB correlates with increased expression of interleukin-6 and promotes progression of gastric carcinoma. Oncology Reports 2013; 29(1) doi: 10.3892/or.2012.2089
44
Zakari Shaibu, Fumeng Yang, Zhihong Chen, Wei Zhu. Investigating the correlation between cytokine levels and prognostic factors in advanced gastric cancer: A systematic review and meta-analysis. Cancer Treatment and Research Communications 2025; 45 doi: 10.1016/j.ctarc.2025.101005
45
Le-Gen Nong, Bin Luo, Liang Zhang, Hong-Bing Nong. Interleukin-18 Gene Promoter Polymorphism and the Risk of Nasopharyngeal Carcinoma in a Chinese Population. DNA and Cell Biology 2009; 28(10) doi: 10.1089/dna.2009.0912
46
Andrzej Szkaradkiewicz, Tomasz M. Karpiński, Michał Drews, Maciej Borejsza-Wysocki, Przemyslaw Majewski, Ewa Andrzejewska. Natural Killer Cell Cytotoxicity and Immunosuppressive Cytokines (IL-10, TGF-β1) in Patients with Gastric Cancer. Journal of Biomedicine and Biotechnology 2010; 2010 doi: 10.1155/2010/901564
47
Manohar Babu Kuppala, Sunayana Begum Syed, Srinivas Bandaru, Sreedevi Varre, Jyothy Akka, Hema Prasad Mundulru. Immunotherapeutic Approach for Better Management of Cancer - Role of IL-18. Asian Pacific Journal of Cancer Prevention 2012; 13(11) doi: 10.7314/APJCP.2012.13.11.5353
48
Yongfen Xu, Hua Li, Wei Chen, Xiaomin Yao, Yue Xing, Xun Wang, Jin Zhong, Guangxun Meng, Suresh Yenugu. Mycoplasma hyorhinis Activates the NLRP3 Inflammasome and Promotes Migration and Invasion of Gastric Cancer Cells. PLoS ONE 2013; 8(11) doi: 10.1371/journal.pone.0077955
49
N. Bouzgarrou, E. Hassen, E. Schvoerer, F. Stoll‐Keller, O. Bahri, S. Gabbouj, I. Cheikh, N. Maamouri, N. Mammi, H. Saffar, A. Trabelsi, H. Triki, L. Chouchane. Association of interleukin‐18 polymorphisms and plasma level with the outcome of chronic HCV infection. Journal of Medical Virology 2008; 80(4) doi: 10.1002/jmv.21079
50
Guohua Yu, Wubin Wang, Xu Wang, Meng Xu, Lili Zhang, Lei Ding, Rui Guo, Yuanyuan Shi. Network pharmacology-based strategy to investigate pharmacological mechanisms of Zuojinwan for treatment of gastritis. BMC Complementary and Alternative Medicine 2018; 18(1) doi: 10.1186/s12906-018-2356-9
51
Kyoko Sakai, Masakazu Kita, Naoki Sawai, Satoshi Shiomi, Yoshio Sumida, Kazuyuki Kanemasa, Shoji Mitsufuji, Jiro Imanishi, Yoshio Yamaoka. Levels of Interleukin‐18 Are Markedly Increased inHelicobacter pylori–Infected Gastric Mucosa among Patients with SpecificIL18Genotypes1. The Journal of Infectious Diseases 2008; 197(12) doi: 10.1086/588196
52
Jorge L. Sepulveda. Molecular Pathology of Neoplastic Gastrointestinal Diseases. Molecular Pathology Library 2013; 7 doi: 10.1007/978-1-4614-6015-2_15
53
Keykavous Parang, Koosha Paydary. Inflammation and detection: Rethinking the biomarker landscape in gastric cancer. World Journal of Clinical Oncology 2025; 16(9): 109717 doi: 10.5306/wjco.v16.i9.109717
54
Anna Maria Orengo, Marina Fabbi, Loredana Miglietta, Cristian Andreani, Milena Bruzzone, Andrea Puppo, Paolo Cristoforoni, Maria Grazia Centurioni, Marina Gualco, Sandra Salvi, Simona Boccardo, Mauro Truini, Tiziana Piazza, Silvana Canevari, Delia Mezzanzanica, Silvano Ferrini. Interleukin (IL)‐18, a biomarker of human ovarian carcinoma, is predominantly released as biologically inactive precursor. International Journal of Cancer 2011; 129(5) doi: 10.1002/ijc.25757
55
Özgür Kemik, Aziz Sümer, Ahu Sarbay Kemik, A Cumhur Dülger, İsmail Hasırcı, Mine Adaş, Sevim Purisa, Sefa Tüzün. Preoperative Serum IL-6 Levels: Clinical Importance in Gastric Carcinoma with Lymph Node Metastasis. Electronic Journal of General Medicine 2010; 7(4) doi: 10.29333/ejgm/82894
56
Zahra Khalili Azni, Matia Sadat Borhani, Hossein Sabouri, Sayed Javad Sajadi, Maryam Pasandideh Arjmand, Zhanzhan Li. Uncovering the molecular landscape of young-onset diffuse gastric cancer: A relieff-based feature selection analysis on RNA-Seq data. PLOS One 2026; 21(8) doi: 10.1371/journal.pone.0354961
57
Magdalena Chechlinska, Maria Kowalska, Janina Kaminska. Cytokines as potential tumour markers. Expert Opinion on Medical Diagnostics 2008; 2(6) doi: 10.1517/17530059.2.6.691