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For: Dai ZJ, Wang XJ, Li ZF, Ji ZZ, Ren HT, Tang W, Liu XX, Kang HF, Guan HT, Song LQ. Scutellaria barbate extract induces apoptosis of hepatoma H22 cells via the mitochondrial pathway involving caspase-3. World J Gastroenterol 2008; 14(48): 7321-7328 [PMID: 19109865 DOI: 10.3748/wjg.14.7321]
URL: https://www.wjgnet.com/1007-9327/full/v14/i48/7321.htm
Number Citing Articles
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Su Su Thae Hnit, Mu Yao, Chanlu Xie, Guangbo Ge, Ling Bi, Shenyi Jin, Lijing Jiao, Ling Xu, Lina Long, Hong Nie, Yu Jin, Linda Rogers, Natalka Suchowerska, Matthew Wong, Tao Liu, Paul De Souza, Zhong Li, Qihan Dong. Transcriptional regulation of G2/M regulatory proteins and perturbation of G2/M Cell cycle transition by a traditional Chinese medicine recipeJournal of Ethnopharmacology 2020; 251: 112526 doi: 10.1016/j.jep.2019.112526
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Chien-Kai Wang, Yi-Feng Lin, Cheng-Jeng Tai, Chia-Wowi Wang, Yu-Jia Chang, Chen-Yen Choong, Chi-Shian Lin, Chen-Jei Tai, Chun-Chao Chang. Integrated Treatment of Aqueous Extract ofSolanum nigrum-Potentiated Cisplatin- and Doxorubicin-Induced Cytotoxicity in Human Hepatocellular Carcinoma CellsEvidence-Based Complementary and Alternative Medicine 2015; 2015: 1 doi: 10.1155/2015/675270
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Neha Sharma, Ashok Kumar, P.R. Sharma, Arem Qayum, Shashank K. Singh, Prabhu Dutt, Satya Paul, Vivek Gupta, M.K. Verma, N.K. Satti, R. Vishwakarma. A new clerodane furano diterpene glycoside from Tinospora cordifolia triggers autophagy and apoptosis in HCT-116 colon cancer cellsJournal of Ethnopharmacology 2018; 211: 295 doi: 10.1016/j.jep.2017.09.034
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Qi-Ling Tang, Ai-Rong Kang, Cong-Xiao Lu. Phytochemical Analysis, Antibacterial Activity and Mode of Action of the Methanolic Extract of Scutellaria barbata Against Various Clinically Important Bacterial PathogensInternational Journal of Pharmacology 2016; 12(2): 116 doi: 10.3923/ijp.2016.116.125
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Josephine Modica-Napolitano, Volkmar Weissig. Treatment Strategies that Enhance the Efficacy and Selectivity of Mitochondria-Targeted Anticancer AgentsInternational Journal of Molecular Sciences 2015; 16(8): 17394 doi: 10.3390/ijms160817394
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Seong Woo Yoon, Jong Soo Jeong, Ji Hye Kim, Bharat B. Aggarwal. Cancer Prevention and TherapyIntegrative Cancer Therapies 2014; 13(4): 310 doi: 10.1177/1534735413510023
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Teng Wang, Chun-yi Lyu, Yue-hua Jiang, Xue-yan Dong, Yan Wang, Zong-hong Li, Jin-xin Wang, Rui-rong Xu. A drug–biomarker interaction model to predict the key targets of Scutellaria barbata D. Don in adverse-risk acute myeloid leukaemiaMolecular Diversity 2021; 25(4): 2351 doi: 10.1007/s11030-020-10124-z
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Tian-Yang Chen, Jing-Yin Mai, Ping Zhang, Jian-Hua Xue, Sheng-Li He, Jun Xi, Jian-Jie Chen, Yang Cheng. Efficacy of erzhu jiedu recipe on hepatitis B cirrhosis with hyperalphafetoproteinemiaMedicine 2021; 100(38): e27231 doi: 10.1097/MD.0000000000027231
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Yanli Wang, Xiaoqing Zhu, Kailiang Wang, Ying Cai, Chunhua Liu, Jie Pan, Jia Sun, Ting Liu, Yong Huang, Yongjun Li, Yuan Lu. Cell metabolomics study on synergistic anti‐hepatocellular carcinoma effect of Aidi injection combined with doxorubicinBiomedical Chromatography 2022; 36(10) doi: 10.1002/bmc.5451
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Brian Y. Y. Wong, Hannah H. L. Wong. Evidence-based Anticancer Materia MedicaEvidence-based Anticancer Complementary and Alternative Medicine 2011; : 155 doi: 10.1007/978-94-007-0526-5_8
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Jelena Klawitter, Jost Klawitter, Jennifer Gurshtein, Kyler Corby, Sylvia Fong, Mary Tagliaferri, Linda Quattrochi, Isaac Cohen, Emma Shtivelman, Uwe Christians. Bezielle (BZL101)‐induced oxidative stress damage followed by redistribution of metabolic fluxes in breast cancer cells: A combined proteomic and metabolomic studyInternational Journal of Cancer 2011; 129(12): 2945 doi: 10.1002/ijc.25965
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Mytre Koul, Ashok Kumar, Ramesh Deshidi, Vishal Sharma, Rachna D. Singh, Jasvinder Singh, Parduman Raj Sharma, Bhahwal Ali Shah, Sundeep Jaglan, Shashank Singh. Cladosporol A triggers apoptosis sensitivity by ROS-mediated autophagic flux in human breast cancer cellsBMC Cell Biology 2017; 18(1) doi: 10.1186/s12860-017-0141-0
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Weixiao An, Honglin Lai, Yangyang Zhang, Minghua Liu, Xiukun Lin, Shousong Cao. Apoptotic Pathway as the Therapeutic Target for Anticancer Traditional Chinese MedicinesFrontiers in Pharmacology 2019; 10 doi: 10.3389/fphar.2019.00758
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Chuan Chen, Zhu Han, Minjie Yang, Zhongke Jiang, Xiuyuan Ou. Induction of apoptosis by Xiakemycin A in human hepatoma HepG2 cellsMedicine 2020; 99(17): e19848 doi: 10.1097/MD.0000000000019848
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Quan-Gui Gao, Jun-Xia Xie, Man-Sau Wong, Wen-Fang Chen. IGF-I receptor signaling pathway is involved in the neuroprotective effect of genistein in the neuroblastoma SK-N-SH cellsEuropean Journal of Pharmacology 2012; 677(1-3): 39 doi: 10.1016/j.ejphar.2011.12.032
16
Jiayu Gao, Weiping Yin, Olivia Corcoran. From Scutellaria barbata to BZL101 in Cancer Patients: Phytochemistry, Pharmacology, and Clinical EvidenceNatural Product Communications 2019; 14(10): 1934578X1988064 doi: 10.1177/1934578X19880645
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Terri Ann Brearley, Brajesh Nanda Vaidya, Nirmal Joshee. Cytokinin, Carbon Source, and Acclimatization Requirements for <i>in Vitro</i> Propagation of <i>Scutellaria barbata</i> D. Don and <i>Scutellaria racemosa</i> Pers.American Journal of Plant Sciences 2014; 5(24): 3662 doi: 10.4236/ajps.2014.524382
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Chin-Chuan Chen, Chun-Pin Kao, Mei-Miao Chiu, Shu-Huei Wang. The anti-cancer effects and mechanisms of Scutellaria barbata D. Don on CL1-5 lung cancer cellsOncotarget 2017; 8(65): 109340 doi: 10.18632/oncotarget.22677
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Ai‐Li Shiau, Yu‐Ting Shen, Jeng‐Long Hsieh, Chao‐Liang Wu, Che‐Hsin Lee. Scutellaria barbata inhibits angiogenesis through downregulation of HIF‐1 α in lung tumorEnvironmental Toxicology 2014; 29(4): 363 doi: 10.1002/tox.21763
20
Zhidong Wang, Jun Li, Yuanyuan Ji, Peng An, Shu Zhang, Zongfang Li. Traditional Herbal Medicine: A Review of Potential of Inhibitory Hepatocellular Carcinoma in Basic Research and Clinical TrialEvidence-Based Complementary and Alternative Medicine 2013; 2013: 1 doi: 10.1155/2013/268963
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Samira EghbaliFeriz, Akram Taleghani, Zahra Tayarani-Najaran. Scutellaria: Debates on the anticancer propertyBiomedicine & Pharmacotherapy 2018; 105: 1299 doi: 10.1016/j.biopha.2018.06.107
22
Li Li, Xiaoyi Xu, Leilei Wu, Haicheng Zhu, Zhipeng He, Bo Zhang, Yanjun Chi, Gaochen Song. Scutellaria barbata polysaccharides inhibit tumor growth and affect the serum proteomic profiling of hepatoma H22‑bearing miceMolecular Medicine Reports 2019;  doi: 10.3892/mmr.2019.9862
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Bing Hu, Hong-Mei An, Xia Yan, Jia-Lu Zheng, Xiao-Wei Huang, Miao Li. Traditional Chinese medicine formulation Yanggan Jiedu Sanjie inhibits TGF-β1-induced epithelial-mesenchymal transition and metastatic potential in human hepatocarcinoma Bel-7402 cellsBMC Complementary and Alternative Medicine 2019; 19(1) doi: 10.1186/s12906-019-2477-9
24
Yu-Chiao Yang, Ming-Chi Wei, Show-Jen Hong, Ting-Chia Huang, Suen-Zone Lee. Development/optimization of a green procedure with ultrasound-assisted improved supercritical carbon dioxide to produce extracts enriched in oleanolic acid and ursolic acid from Scutellaria barbata D. DonIndustrial Crops and Products 2013; 49: 542 doi: 10.1016/j.indcrop.2013.05.013
25
Wei Yan, Dan-Dan Li, Dan Liu, Hong-Mei Li, Zhi-Jun Zhang, Rong-Tao Li, Xuan-Qin Chen. Neo-clerodane diterpenoids from Scutellaria barbata and their reversal multidrug resistance activity in HepG2/Adr cellsPhytochemistry Letters 2020; 35: 128 doi: 10.1016/j.phytol.2019.11.014
26
Yameng Zhang, Chao Li, Shanmei Sun, Zhiqun Cao, Jian Chen, Hongjie Xiang, Lucheng Song. Screening and Identification of Molecular Targets Involved in Preventing Gastric Precancerous Lesions in Chronic Atrophic Gastritis by Qilianshupi DecoctionEvidence-Based Complementary and Alternative Medicine 2019; 2019: 1 doi: 10.1155/2019/5804710
27
Crystal N. Marconett, Travis J. Morgenstern, Adrianna K. San Roman, Shyam N. Sundar, Ankur K. Singhal, Gary L. Firestone. BZL101, a phytochemical extract from theScutellaria barbataplant, disrupts proliferation of human breast and prostate cancer cells through distinct mechanisms dependent on the cancer cell phenotypeCancer Biology & Therapy 2010; 10(4): 397 doi: 10.4161/cbt.10.4.12424
28
Qiong Chen, Khalid Rahman, Su-Juan Wang, Shuang Zhou, Hong Zhang. Scutellaria barbata: A Review on Chemical Constituents, Pharmacological Activities and Clinical ApplicationsCurrent Pharmaceutical Design 2020; 26(1): 160 doi: 10.2174/1381612825666191216124310
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Zhi-Jun Dai, Bao-Feng Wang, Wang-Feng Lu, Zhi-Dong Wang, Xiao-Bin Ma, Wei-Li Min, Hua-Feng Kang, Xi-Jing Wang, Wen-Ying Wu. Total Flavonoids of Scutellaria barbata Inhibit Invasion of Hepatocarcinoma via MMP/TIMP in VitroMolecules 2013; 18(1): 934 doi: 10.3390/molecules18010934
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Ranjita Misra, Manasi Das, Bhabani Sankar Sahoo, Sanjeeb K. Sahoo. Reversal of multidrug resistance in vitro by co-delivery of MDR1 targeting siRNA and doxorubicin using a novel cationic poly(lactide-co-glycolide) nanoformulationInternational Journal of Pharmaceutics 2014; 475(1-2): 372 doi: 10.1016/j.ijpharm.2014.08.056
31
Ao‐Chun Yue, Xu‐Dong Zhou, Hui‐Ping Song, Xu‐Han Liu, Ming‐Jun Bi, Wei Han, Qin Li. Effect and molecular mechanism of Sulforaphane alleviates brain damage caused by acute carbon monoxide poisoning:Network pharmacology analysis, molecular docking, and experimental evidenceEnvironmental Toxicology 2024; 39(3): 1140 doi: 10.1002/tox.24000
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Rong Gao, Jie Ma, Zhifa Wen, Peiying Yang, Jinjin Zhao, Meng Xue, Yongqiang Chen, Mohanad Aldarouish, Hong-Ming Hu, Xue-Jun Zhu, Ning Pan, Li-Xin Wang. Tumor cell-released autophagosomes (TRAP) enhance apoptosis and immunosuppressive functions of neutrophilsOncoImmunology 2018; 7(6) doi: 10.1080/2162402X.2018.1438108
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Xian-qian Li, Shi-he Shao, Gui-lian Fu, Xiao-hong Han, Hong Gao. Study on norcantharidin-induced apoptosis in SMMC-7721 cells through mitochondrial pathwaysChinese Journal of Integrative Medicine 2010; 16(5): 448 doi: 10.1007/s11655-010-0538-5
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Zhi-Jun Dai, Jie Gao, Zong-Fang Li, Zong-Zheng Ji, Hua-Feng Kang, Hai-Tao Guan, Yan Diao, Bao-Feng Wang, Xi-Jing Wang. In Vitro and In Vivo Antitumor Activity of Scutellaria barbate Extract on Murine Liver CancerMolecules 2011; 16(6): 4389 doi: 10.3390/molecules16064389
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Aijing Bi, Zhen Guo, Guocui Yang, Youfang Huang, Zhimin Yin, Lan Luo. γ-glutamylcysteine suppresses cadmium-induced apoptosis in PC12 cells via regulating oxidative stressToxicology 2022; 465: 153029 doi: 10.1016/j.tox.2021.153029
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Yongqiang Chen, Jinjuan Liu, Bo Yuan, Chengliang Cao, Sheng Qin, Xiaoying Cao, Guangkai Bian, Zhe Wang, Jihong Jiang. Methylated actinomycin D, a novel actinomycin D analog induces apoptosis in HepG2 cells through Fas‐ and mitochondria‐mediated pathwaysMolecular Carcinogenesis 2013; 52(12): 983 doi: 10.1002/mc.21943
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Ravindra Dhar Dubey, Ankit Saneja, Arem Qayum, Amarinder Singh, Girish Mahajan, Gousia Chashoo, Amit Kumar, Samar S. Andotra, Shashank K. Singh, Gurdarshan Singh, Surinder Koul, Dilip M. Mondhe, Prem N. Gupta. PLGA nanoparticles augmented the anticancer potential of pentacyclic triterpenediol in vivo in miceRSC Advances 2016; 6(78): 74586 doi: 10.1039/C6RA14929D
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Ning Yang, Yuying Zhao, Zhipeng Wang, Yu Liu, Yanqiao Zhang. Scutellarin suppresses growth and causes apoptosis of human colorectal cancer cells by regulating the p53 pathwayMolecular Medicine Reports 2017; 15(2): 929 doi: 10.3892/mmr.2016.6081
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Jie Gao, Wang-Feng Lu, Zhi-Jun Dai, Shuai Lin, Yang Zhao, Sha Li, Nuan-Nuan Zhao, Xi-Jing Wang, Hua-Feng Kang, Xiao-Bin Ma, Wang-Gang Zhang. Induction of apoptosis by total flavonoids from Scutellaria barbata D. Don in human hepatocarcinoma MHCC97-H cells via the mitochondrial pathwayTumor Biology 2014; 35(3): 2549 doi: 10.1007/s13277-013-1336-4
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Xiao-Shun Gong, Rui-Jian Jiang, Xia-Li Liao, Hu-Die Xie, Xue Ma, Chuan-Zhu Gao, Bo Yang, Yu-Lin Zhao. Synthesis, characterization and in vitro evaluation of a series of novel polyrotaxane-based delivery system for artesunateCarbohydrate Research 2015; 412: 7 doi: 10.1016/j.carres.2015.04.021
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Ngoc-Ha Bui-Xuan, Patrick Ming-Kuen Tang, Chun-Kwok Wong, Kwok-Pui Fung. Photo-activated pheophorbide-a, an active component of Scutellaria barbata, enhances apoptosis via the suppression of ERK-mediated autophagy in the estrogen receptor-negative human breast adenocarcinoma cells MDA-MB-231Journal of Ethnopharmacology 2010; 131(1): 95 doi: 10.1016/j.jep.2010.06.007
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Wafaa Ahmed, Dina Mofed, Abdel-Rahman Zekri, Nasr El-Sayed, Mohamed Rahouma, Salwa Sabet. Antioxidant activity and apoptotic induction as mechanisms of action of Withania somnifera (Ashwagandha) against a hepatocellular carcinoma cell lineJournal of International Medical Research 2018; 46(4): 1358 doi: 10.1177/0300060517752022
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Ming-Rong Cao, Qiang Li, Zhi-Long Liu, Hui-Hui Liu, Wei Wang, Xiao-Li Liao, Yun-Long Pan, Jian-Wei Jiang. Harmine induces apoptosis in HepG2 cells via mitochondrial signaling pathwayHepatobiliary & Pancreatic Diseases International 2011; 10(6): 599 doi: 10.1016/S1499-3872(11)60102-1
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Liu-Lin Xiong, Ruo-Lan Du, Lu-Lu Xue, Ya Jiang, Jin Huang, Li Chen, Jia Liu, Ting-Hua Wang. Anti-colorectal cancer effects of scutellarin revealed by genomic and proteomic analysisChinese Medicine 2020; 15(1) doi: 10.1186/s13020-020-00307-z
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Ashok Kumar, Baljinder Singh, Girish Mahajan, Parduman R. Sharma, Sandip B. Bharate, Mubashir J. Mintoo, Dilip M. Mondhe. A novel colchicine-based microtubule inhibitor exhibits potent antitumor activity by inducing mitochondrial mediated apoptosis in MIA PaCa-2 pancreatic cancer cellsTumor Biology 2016; 37(10): 13121 doi: 10.1007/s13277-016-5160-5
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Grace Gar‐Lee Yue, Yuk‐Yu Chan, Wenjing Liu, Si Gao, Chun‐Wai Wong, Julia Kin‐Ming Lee, Kit‐Man Lau, Clara Bik‐San Lau. Effectiveness of Scutellaria barbata water extract on inhibiting colon tumor growth and metastasis in tumor‐bearing micePhytotherapy Research 2021; 35(1): 361 doi: 10.1002/ptr.6808
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Rui-Jian Jiang, Bo Yang, Zhen-Kun Liu, Yu-Lin Zhao, Xia-Li Liao, Jian Yang, Chuan-Zhu Gao, Fen Wang, Bin Han. A novel polyrotaxane-based delivery system for scutellarin: preparation, characterization, and in vitro evaluationCarbohydrate Research 2013; 380: 149 doi: 10.1016/j.carres.2013.07.009
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Jue Zhang, Hyeon-Soo Park, Jin-A Kim, Gyeong-Eun Hong, ArulKumar Nagappan, Kwang-Il Park, Gon-Sup Kim. Flavonoids Identified from Korean Scutellaria baicalensis Induce Apoptosis by ROS Generation and Caspase Activation on Human Fibrosarcoma CellsThe American Journal of Chinese Medicine 2014; 42(02): 465 doi: 10.1142/S0192415X14500311
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Shalini Mani, Geeta Swargiary, Keshav K. Singh. Natural Agents Targeting Mitochondria in CancerInternational Journal of Molecular Sciences 2020; 21(19): 6992 doi: 10.3390/ijms21196992
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Zong-Fang Li, Zhi-Dong Wang, Yuan-Yuan Ji, Shu Zhang, Chen Huang, Jun Li, Xian-Ming Xia. Induction of apoptosis and cell cycle arrest in human HCC MHCC97H cells with <italic>Chrysanthemum indicum</italic> extractWorld Journal of Gastroenterology 2009; 15(36): 4538-4546 doi: 10.3748/wjg.15.4538