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For: Kalra M, Mayes J, Assefa S, Kaul AK, Kaul R. Role of sex steroid receptors in pathobiology of hepatocellular carcinoma. World J Gastroenterol 2008; 14(39): 5945-5961 [PMID: 18932272 DOI: 10.3748/wjg.14.5945]
URL: https://www.wjgnet.com/1007-9327/full/v14/i39/5945.htm
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Number Citing Articles
1
Nicholas J. Lodato, Tisha Melia, Andy Rampersaud, David J. Waxman. Sex-Differential Responses of Tumor Promotion-Associated Genes and Dysregulation of Novel Long Noncoding RNAs in Constitutive Androstane Receptor-Activated Mouse Liver. Toxicological Sciences 2017; 159(1) doi: 10.1093/toxsci/kfx114
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Min Dai, Rashid N. Lui, Louis H.S. Lau. The role of gut microbiome and fecal microbiota transplantation in liver cancer and related complications: mechanisms and therapeutic potentials. Hepatoma Research 2023;  doi: 10.20517/2394-5079.2023.33
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Guoxiang Xie, Xiaoning Wang, Aihua Zhao, Jingyu Yan, Wenlian Chen, Runqiu Jiang, Junfang Ji, Fengjie Huang, Yunjing Zhang, Sha Lei, Kun Ge, Xiaojiao Zheng, Cynthia Rajani, Rosanna A. Alegado, Jiajian Liu, Ping Liu, Jeremy Nicholson, Wei Jia. Sex-dependent effects on gut microbiota regulate hepatic carcinogenic outcomes. Scientific Reports 2017; 7(1) doi: 10.1038/srep45232
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Anisha Jain, Satdarshan P. Monga. Sexual dimorphism in the liver. Nature Reviews Gastroenterology & Hepatology 2026;  doi: 10.1038/s41575-026-01244-2
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Anees M. Dauki, James S. Blachly, Esko A. Kautto, Sameera Ezzat, Mohamed H. Abdel-Rahman, Christopher C. Coss. Transcriptionally Active Androgen Receptor Splice Variants Promote Hepatocellular Carcinoma Progression. Cancer Research 2020; 80(3) doi: 10.1158/0008-5472.CAN-19-1117
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Shenglan Gao, Aimin Li, Feiye Liu, Fengsheng Chen, Mark Williams, Chengliang Zhang, Zakiya Kelley, Chin-Lee Wu, Rongcheng Luo, Hua Xiao. NCOA5 Haploinsufficiency Results in Glucose Intolerance and Subsequent Hepatocellular Carcinoma. Cancer Cell 2013; 24(6) doi: 10.1016/j.ccr.2013.11.005
7
Tatsuo Kido, Yun-Fai Chris Lau. The Y-linked proto-oncogene TSPY contributes to poor prognosis of the male hepatocellular carcinoma patients by promoting the pro-oncogenic and suppressing the anti-oncogenic gene expression. Cell & Bioscience 2019; 9(1) doi: 10.1186/s13578-019-0287-x
8
Kimberley D. Katleba, Paramita M. Ghosh, Maria Mudryj. Beyond Prostate Cancer: An Androgen Receptor Splice Variant Expression in Multiple Malignancies, Non-Cancer Pathologies, and Development. Biomedicines 2023; 11(8) doi: 10.3390/biomedicines11082215
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Tu Tuan Tran, Huy The Be, Khanh Dinh Hoang, Hoang Duc Dong. Sex and gender disparities in hepatocellular carcinoma: insights into risk, diagnosis, and therapeutic outcomes. Clinical and Translational Oncology 2025; 27(12) doi: 10.1007/s12094-025-03965-3
10
Bo Zheng, Yan-Jing Zhu, Hong-Yang Wang, Lei Chen. Gender disparity in hepatocellular carcinoma (HCC): multiple underlying mechanisms. Science China Life Sciences 2017; 60(6) doi: 10.1007/s11427-016-9043-9
11
Shuko Hata, Yasuhiro Miki, Ryoko Saito, Kazuyuki Ishida, Mika Watanabe, Hironobu Sasano. Aromatase in human liver and its diseases. Cancer Medicine 2013; 2(3) doi: 10.1002/cam4.85
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Ewa Wolinska, Maciej Skrzypczak. Epigenetic Changes Affecting the Development of Hepatocellular Carcinoma. Cancers 2021; 13(16) doi: 10.3390/cancers13164237
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Nabil Mohie Abdel-Hamid, Rawaa Muayad Al-Quzweny. Prevalence of Hepatocellular Carcinoma in Men and the Contribution of Androgen and its Receptor in Pathogenesis and Therapy. Current Molecular Pharmacology 2023; 16(5) doi: 10.2174/1874467215666221010092825
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Cho Naing, Han Ni, Htar Htar Aung, Joon Wah Mak. Tamoxifen for hepatocellular carcinoma. Cochrane Database of Systematic Reviews 2021;  doi: 10.1002/14651858.CD014869
15
Michele Vacca, Chiara Degirolamo, Vittoria Massafra, Lorenzo Polimeno, Renato Mariani-Costantini, Giuseppe Palasciano, Antonio Moschetta. Nuclear receptors in regenerating liver and hepatocellular carcinoma. Molecular and Cellular Endocrinology 2013; 368(1-2) doi: 10.1016/j.mce.2012.06.025
16
Janaki K Iyer, Mamta Kalra, Anil Kaul, Mark E Payton, Rashmi Kaul. Estrogen receptor expression in chronic hepatitis C and hepatocellular carcinoma pathogenesis. World Journal of Gastroenterology 2017; 23(37): 6802-6816 doi: 10.3748/wjg.v23.i37.6802
17
Manri Kawakami, Yasuhiro Umekawa. A female patient developing hepatocellular carcinoma 4.5 years after sustained virological response to interferon therapy for chronic hepatitis C: Comparison with cases of male patients. Kanzo 2011; 52(11) doi: 10.2957/kanzo.52.722
18
Nicole E. Rich, Caitlin C. Murphy, Adam C. Yopp, Jasmin Tiro, Jorge A. Marrero, Amit G. Singal. Sex disparities in presentation and prognosis of 1110 patients with hepatocellular carcinoma. Alimentary Pharmacology & Therapeutics 2020; 52(4) doi: 10.1111/apt.15917
19
Lian Li, Liangliang Xu, Tianfu Wen, Hong Wu, Wentao Wang, Jiayin Yang, Zheyu Chen, Yonggang Wei, Mingqing Xu, Bo Li, Ming Zhang. Poor Prognoses of Young Hepatocellular Carcinoma Patients with Microvascular Invasion: A Propensity Score Matching Cohort Study. Gastroenterology Research and Practice 2020; 2020 doi: 10.1155/2020/4691425
20
Latifa Bakiri, Erwin F. Wagner. Mouse models for liver cancer. Molecular Oncology 2013; 7(2) doi: 10.1016/j.molonc.2013.01.005
21
Yan Li, Hankun Li, Jan M. Spitsbergen, Zhiyuan Gong. Males develop faster and more severe hepatocellular carcinoma than females in krasV12 transgenic zebrafish. Scientific Reports 2017; 7(1) doi: 10.1038/srep41280
22
Arup Banerjee, Ratna B. Ray, Ranjit Ray. Oncogenic Potential of Hepatitis C Virus Proteins. Viruses 2010; 2(9) doi: 10.3390/v2092108
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Zhaoyu Li, Geetu Tuteja, Jonathan Schug, Klaus H. Kaestner. Foxa1 and Foxa2 Are Essential for Sexual Dimorphism in Liver Cancer. Cell 2012; 148(1-2) doi: 10.1016/j.cell.2011.11.026
24
Hong Zhang, Xiao‐Xing Li, Yang Yang, Yanjie Zhang, Hui‐Yun Wang, X.F. Steven Zheng. Significance and mechanism of androgen receptor overexpression and androgen receptor/mechanistic target of rapamycin cross‐talk in hepatocellular carcinoma. Hepatology 2018; 67(6) doi: 10.1002/hep.29715
25
Aurélie Vega, Marine Baptissart, Emmanuelle Martinot, Jean-Paul Saru, Silvère Baron, Kristina Schoonjans, David H Volle. Hepatotoxicity induced by neonatal exposure to diethylstilbestrol is maintained throughout adulthood via the nuclear receptor SHP. Expert Opinion on Therapeutic Targets 2014;  doi: 10.1517/14728222.2014.964209
26
Yuxiao Liao, Zhao Peng, Liangkai Chen, Andreas K. Nüssler, Liegang Liu, Wei Yang. Deoxynivalenol, gut microbiota and immunotoxicity: A potential approach?. Food and Chemical Toxicology 2018; 112 doi: 10.1016/j.fct.2018.01.013
27
Arthur Zimmermann. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. 2016;  doi: 10.1007/978-3-319-26587-2_164-1
28
A. Mallat. Post’U FMC-HGE. 2010;  doi: 10.1007/978-2-8178-0097-4_34
29
Fung-Yu Huang, Danny Ka-Ho Wong, Wai-Kay Seto, Ching-Lung Lai, Man-Fung Yuen. Estradiol induces apoptosis via activation of miRNA-23a and p53: implication for gender difference in liver cancer development. Oncotarget 2015; 6(33) doi: 10.18632/oncotarget.5472
30
Mrittika Chattopadhyay, Edmund Charles Jenkins, Ana Victoria Lechuga-Vieco, Kai Nie, Maria Isabel Fiel, Alexander Rialdi, Ernesto Guccione, Jose Antonio Enriquez, Daniela Sia, Amaia Lujambio, Doris Germain. The Portrait of Liver Cancer is Shaped by Mitochondrial Genetics. SSRN Electronic Journal 2021;  doi: 10.2139/ssrn.3869891
31
S Assefa, JT Curtis, S Sethi, RL Davis, Y Chen, R Kaul. Inorganic mercury exposure in prairie voles (Microtus ochrogaster) alters the expression of toll-like receptor 4 and activates inflammatory pathways in the liver in a sex-specific manner. Human & Experimental Toxicology 2012; 31(4) doi: 10.1177/0960327111407223
32
Hui Ren, Bo Ren, Jiabin Zhang, Xiaofeng Zhang, Lixin Li, Lingzhan Meng, Zhijie Li, Jia Li, Yinjie Gao, Xuemei Ma. Androgen enhances the activity of ETS-1 and promotes the proliferation of HCC cells. Oncotarget 2017; 8(65) doi: 10.18632/oncotarget.22669
33
Xing Gu, Peng Qi, Feiguo Zhou, Qiang Ji, Hao Wang, Tonghai Dou, Yunpeng Zhao, Chunfang Gao. +49G > A polymorphism in the cytotoxic T-lymphocyte antigen-4 gene increases susceptibility to hepatitis B-related hepatocellular carcinoma in a male Chinese population. Human Immunology 2010; 71(1) doi: 10.1016/j.humimm.2009.09.353
34
Xuan Shao, Yongqing Wang, Yanlei Liu, Xuejiang Guo, Dong Li, Ran Huo, Wentong Jia, Guangming Cao, Yu-Xia Li, Ming Liu, Jiahao Sha, Yangyu Zhao, Yan-Ling Wang. Association of imbalanced sex hormone production with excessive procoagulation factor SerpinF2 in preeclampsia. Journal of Hypertension 2019; 37(1) doi: 10.1097/HJH.0000000000001862
35
Changcheng Yang, Juefu Hu, Liang Yao, Yang Yu, Xiaoying Dong, Jun Chen, Aiguo Wang, Huiling Li. Comprehensive phosphoproteomic profiling reveals sex-specific regulatory mechanisms in HrasG12V-driven hepatocarcinogenesis. Cancer Cell International 2025; 25(1) doi: 10.1186/s12935-025-04015-2
36
Giuseppe Carruba. Estrogens in Hepatocellular Carcinoma: Friends or Foes?. Cancers 2021; 13(9) doi: 10.3390/cancers13092085
37
Wan Sun, Changchang Hu, Tianyu Wang, Juan Wang, Jieping Zhang, Furong Gao, Qingjian Ou, Haibin Tian, Caixia Jin, Jingying Xu, Jingfa Zhang, Guo-Tong Xu, Lixia Lu. Glia Maturation Factor Beta as a Novel Biomarker and Therapeutic Target for Hepatocellular Carcinoma. Frontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.744331
38
C Chang, S O Lee, S Yeh, T M Chang. Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver. Oncogene 2014; 33(25) doi: 10.1038/onc.2013.274
39
Lupin Jiang, Juanjuan Shan, Junjie Shen, Yanzhou Wang, Ping Yan, Limei Liu, Wenxu Zhao, Yanmin Xu, Wei Zhu, Li Su, Jun Chen, Feifei Cheng, Hong Yao, Huicheng Xu, Cheng Qian, Zhiqing Liang. Androgen/androgen receptor axis maintains and promotes cancer cell stemness through direct activation of Nanog transcription in hepatocellular carcinoma. Oncotarget 2016; 7(24) doi: 10.18632/oncotarget.9192
40
Xiaotao Zhang, Hashem B. El-Serag, Aaron P. Thrift. Sex and Race Disparities in the Incidence of Hepatocellular Carcinoma in the United States Examined through Age–Period–Cohort Analysis. Cancer Epidemiology, Biomarkers & Prevention 2020; 29(1) doi: 10.1158/1055-9965.EPI-19-1052
41
Won Kim. Sex/Gender-Specific Medicine in the Gastrointestinal Diseases. 2022;  doi: 10.1007/978-981-19-0120-1_15
42
Sarah Groover, Sarah Addison, Savannah Nicks, Mitchelle Mwangi, Amy Brooks, Anil Kaul, Rashmi Kaul. Sex based relative expression of estrogen receptors and tumor necrosis factor-alpha in liver affects hepatitis C virus viral pathogenesis. World Journal of Gastroenterology 2025; 31(32): 104277 doi: 10.3748/wjg.v31.i32.104277
43
Michael Schweizer, Evan Yu. AR-Signaling in Human Malignancies: Prostate Cancer and Beyond. Cancers 2017; 9(1) doi: 10.3390/cancers9010007
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YE TIAN, XU XIE, YAO LIN, GUANG TAN, WU ZHONG. Androgen receptor in hepatocarcinogenesis: Recent developments and perspectives. Oncology Letters 2015; 9(5) doi: 10.3892/ol.2015.3025
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Shaimaa Bakr, Kevin Brennan, Pritam Mukherjee, Josepmaria Argemi, Mikel Hernaez, Olivier Gevaert. Identifying key multifunctional components shared by critical cancer and normal liver pathways via SparseGMM. Cell Reports Methods 2023; 3(1) doi: 10.1016/j.crmeth.2022.100392
46
Anna Ruggieri, Cristiana Barbati, Walter Malorni. Cellular and molecular mechanisms involved in hepatocellular carcinoma gender disparity. International Journal of Cancer 2010; 127(3) doi: 10.1002/ijc.25298
47
Gundula Behrens, Charles E. Matthews, Steven C. Moore, Neal D. Freedman, Katherine A. McGlynn, James E. Everhart, Albert R. Hollenbeck, Michael F. Leitzmann. The association between frequency of vigorous physical activity and hepatobiliary cancers in the NIH-AARP Diet and Health Study. European Journal of Epidemiology 2013; 28(1) doi: 10.1007/s10654-013-9767-1
48
Francesca Giunchi, Francesco Vasuri, Michelangelo Fiorentino. Pathology and Epidemiology of Cancer. 2017;  doi: 10.1007/978-3-319-35153-7_23
49
Sharon N. DeWitte. Sex differentials in frailty in medieval England. American Journal of Physical Anthropology 2010; 143(2) doi: 10.1002/ajpa.21316
50
Tatsuo Kido, Z. Laura Tabatabai, Xin Chen, Yun‐Fai Chris Lau. Potential dual functional roles of the Y‐linked RBMY in hepatocarcinogenesis. Cancer Science 2020; 111(8) doi: 10.1111/cas.14506
51
Ilkyu Park, Nakyoung Kim, Sugi Lee, Kunhyang Park, Mi-Young Son, Hyun-Soo Cho, Dae-Soo Kim. Characterization of signature trends across the spectrum of non-alcoholic fatty liver disease using deep learning method. Life Sciences 2023; 314 doi: 10.1016/j.lfs.2022.121195
52
Emma J. Montgomery, Enming Xing, Moray J. Campbell, Pui-Kai Li, James S. Blachly, Allan Tsung, Christopher C. Coss. Constitutively Active Androgen Receptor in Hepatocellular Carcinoma. International Journal of Molecular Sciences 2022; 23(22) doi: 10.3390/ijms232213768
53
Qing Wei, Pengbo Guo, Kun Mu, Ying Zhang, Wei Zhao, Wanwan Huai, Yumin Qiu, Tao Li, Xiaomin Ma, Yafei Liu, Xiaoyan Chen, Lihui Han. Estrogen suppresses hepatocellular carcinoma cells through ERβ-mediated upregulation of the NLRP3 inflammasome. Laboratory Investigation 2015; 95(7) doi: 10.1038/labinvest.2015.63
54
Junping Ao, Jiao Meng, Lei Zhu, Huizhen Nie, Chenchen Yang, Jinjun Li, Jianren Gu, Qiushi Lin, Weiwen Long, Xiaoqun Dong, Chao Li. Activation of androgen receptor induces ID1 and promotes hepatocellular carcinoma cell migration and invasion. Molecular Oncology 2012; 6(5) doi: 10.1016/j.molonc.2012.06.005
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Liang Shi, Yili Feng, Hui Lin, Rui Ma, Xiujun Cai. Role of estrogen in hepatocellular carcinoma: is inflammation the key?. Journal of Translational Medicine 2014; 12(1) doi: 10.1186/1479-5876-12-93
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Qingshan Chang, Jianguo Chen, Kevin J Beezhold, Vince Castranova, Xianglin Shi, Fei Chen. JNK1 activation predicts the prognostic outcome of the human hepatocellular carcinoma. Molecular Cancer 2009; 8(1) doi: 10.1186/1476-4598-8-64
57
Yao-Tsung Yeh, Chien-Wei Chang, Ren-Jie Wei, Shen-Nien Wang. Progesterone and Related Compounds in Hepatocellular Carcinoma: Basic and Clinical Aspects. BioMed Research International 2013; 2013 doi: 10.1155/2013/290575
58
Qian Zhong, Shaoyan Xi, Jianzhong Liang, Ganggang Shi, Yi Huang, Yanmei Zhang, Daniel Levy, Shuping Zhong. The significance of Brf1 overexpression in human hepatocellular carcinoma. Oncotarget 2016; 7(5) doi: 10.18632/oncotarget.6668
59
Ruey-Shyang Soong, Ming-Chin Yu, Kun-Ming Chan, Hong-Shiue Chou, Ting-Jung Wu, Chen-Fang Lee, Tsung-Han Wu, Wei-Chen Lee. Analysis of the recurrence risk factors for the patients with hepatocellular carcinoma meeting University of California San Francisco criteria after curative hepatectomy. World Journal of Surgical Oncology 2011; 9(1) doi: 10.1186/1477-7819-9-9
60
Arthur Zimmermann. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. 2017;  doi: 10.1007/978-3-319-26956-6_164
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Fangfang Chen, Xiaoqing Chen, Fan Jiang, Feng Leng, Wei Liu, Yaoting Gui, Jing Yu. Computational analysis of androgen receptor (AR) variants to decipher the relationship between protein stability and related-diseases. Scientific Reports 2020; 10(1) doi: 10.1038/s41598-020-68731-7
62
Yunfeng Yi, Chenghao Huang, Yanmei Zhang, Suke Tian, Junxia Lei, Songlin Chen, Ganggang Shi, Zhongdao Wu, Ningshao Xia, Shuping Zhong. Exploring a common mechanism of alcohol-induced deregulation of RNA Pol III genes in liver and breast cells. Gene 2017; 626 doi: 10.1016/j.gene.2017.05.048
63
Hankun Li, Jeng-Wei Lu, Xiaojing Huo, Yan Li, Zhen Li, Zhiyuan Gong. Effects of sex hormones on liver tumor progression and regression in Myc/xmrk double oncogene transgenic zebrafish. General and Comparative Endocrinology 2019; 277 doi: 10.1016/j.ygcen.2019.03.018
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Stephanie Cauble, Ali Abbas, Luis Balart, Lydia Bazzano, Sabeen Medvedev, Nathan Shores. United States Women Receive More Curative Treatment for Hepatocellular Carcinoma Than Men. Digestive Diseases and Sciences 2013; 58(10) doi: 10.1007/s10620-013-2731-9
65
Marco Marzioni, Alessia Torrice, Stefania Saccomanno, Chiara Rychlicki, Laura Agostinelli, Irene Pierantonelli, Patrik Rhönnstad, Luciano Trozzi, Theresa Apelqvist, Raffaele Gentile, Cinzia Candelaresi, Giammarco Fava, Rossella Semeraro, Antonio Benedetti, Eugenio Gaudio, Antonio Franchitto, Paolo Onori, Samuele De Minicis, Guido Carpino, Elisabet Kallin, Domenico Alvaro, Stefan Nilsson. An oestrogen receptor β-selective agonist exerts anti-neoplastic effects in experimental intrahepatic cholangiocarcinoma. Digestive and Liver Disease 2012; 44(2) doi: 10.1016/j.dld.2011.06.014
66
Lilian Rego de Carvalho, Andrea Borrego, José Ricardo Jensen, Wafa Hanna Koury Cabrera, Aline Marques Santos, Orlando Garcia Ribeiro, Nancy Starobinas, Marcelo De Franco, Tommaso A. Dragani, Giacomo Manenti, Olga Célia Martinez Ibañez. Genetic Predisposition to Hepatocarcinogenesis in Inbred and Outbred Mouse Lines Selected for High or Low Inflammatory Response. Journal of Immunology Research 2019; 2019 doi: 10.1155/2019/5298792
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Jonathan F. Goodwin, Matthew J. Schiewer, Jeffry L. Dean, Randy S. Schrecengost, Renée de Leeuw, Sumin Han, Teng Ma, Robert B. Den, Adam P. Dicker, Felix Y. Feng, Karen E. Knudsen. A Hormone–DNA Repair Circuit Governs the Response to Genotoxic Insult. Cancer Discovery 2013; 3(11) doi: 10.1158/2159-8290.CD-13-0108
68
Richard S. Judson, Keith A. Houck, Robert J. Kavlock, Thomas B. Knudsen, Matthew T. Martin, Holly M. Mortensen, David M. Reif, Daniel M. Rotroff, Imran Shah, Ann M. Richard, David J. Dix. In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project. Environmental Health Perspectives 2010; 118(4) doi: 10.1289/ehp.0901392
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Wen-Lung Ma, Hsueh-Chou Lai, Shuyuan Yeh, Xiujun Cai, Chawnshang Chang. Androgen receptor roles in hepatocellular carcinoma, fatty liver, cirrhosis and hepatitis. Endocrine-Related Cancer 2014; 21(3) doi: 10.1530/ERC-13-0283
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T. El Mahdy Korah, E. Abd Elfatah Badr, M. Mohamed Emara, M. Ahmed Samy Kohla, G. Gamal Saad Michael. Relation between sex hormones and hepatocellular carcinoma. Andrologia 2016; 48(9) doi: 10.1111/and.12536
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Ping Jiang, Jun Cao, Wen-Hui Bai. Lentivirus-Mediated siRNA Targeting ER-αInhibits Tumorigenesis and Induces Apoptosis in Hepatocarcinoma Cells. BioMed Research International 2015; 2015 doi: 10.1155/2015/490681
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Jae Heon Kim, Gi Hwan Bae, Jaehun Jung, Tae Il Noh. Secondary Cancer after Androgen Deprivation Therapy in Prostate Cancer: A Nationwide Study. The World Journal of Men's Health 2025; 43(1) doi: 10.5534/wjmh.230237
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Yongbing Zhao, Zhaoyu Li. Interplay of estrogen receptors and FOXA factors in the liver cancer. Molecular and Cellular Endocrinology 2015; 418 doi: 10.1016/j.mce.2015.01.043
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Zhen Yuan, Mu Ye, Jingbo Qie, Tao Ye. <p>FOXA1 Promotes Cell Proliferation and Suppresses Apoptosis in HCC by Directly Regulating miR-212-3p/FOXA1/AGR2 Signaling Pathway</p>. OncoTargets and Therapy 2020;  doi: 10.2147/OTT.S252890
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Eriko Tanabe, Ayano Shibata, Serina Inoue, Misaho Kitayoshi, Nobuyuki Fukushima, Toshifumi Tsujiuchi. Regulation of cell motile activity through the different induction of LPA receptors by estrogens in liver epithelial WB-F344 cells. Biochemical and Biophysical Research Communications 2012; 428(1) doi: 10.1016/j.bbrc.2012.10.015
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Yong-Ping Yang, Cheng-Jun Guo, Zhao-Xuan Gu, Jun-Jie Hua, Jia-Xuan Zhang, Jian Shi. Conditional survival probability of distant-metastatic hepatocellular carcinoma: A population-based study. World Journal of Gastrointestinal Oncology 2023; 15(11): 1874-1890 doi: 10.4251/wjgo.v15.i11.1874
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Juan Guo, Yanjun Zhang, Jie Zhang, Jun Liang, Lihua Zeng, Guozhen Guo. Anticancer effect of tert-butyl-2(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2)-pyrrolidine-1-carboxylic ester on human hepatoma HepG2 cell line. Chemico-Biological Interactions 2012; 199(1) doi: 10.1016/j.cbi.2012.06.001
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Maureen P. Kohi. Gender-Related Differences in Hepatocellular Carcinoma: Does Sex Matter?. Journal of Vascular and Interventional Radiology 2016; 27(9) doi: 10.1016/j.jvir.2016.06.035
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Chun-Hsiang Wang, Ruey-Chang Lin, Hua-Yin Hsu, Yuan-Tsung Tseng, Yann Benetreau. Hormone replacement therapy is associated with reduced hepatocellular carcinoma risk and improved survival in postmenopausal women with hepatitis B: A nationwide long-term population-based cohort study. PLOS ONE 2022; 17(7) doi: 10.1371/journal.pone.0271790
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Farzaneh Rostamzadeh, Mahboobeh Yeganeh-Hajahmadi, Yasmin Moosavi-Saeed. Klotho-gonadal hormone crosstalk in male and female reproduction. Biology of Reproduction 2025; 113(5) doi: 10.1093/biolre/ioaf181
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Hankun Li, Yan Li, Jeng-Wei Lu, Xiaojing Huo, Zhiyuan Gong. Liver-specific androgen receptor knockout attenuates early liver tumor development in zebrafish. Scientific Reports 2019; 9(1) doi: 10.1038/s41598-019-46378-3
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YE TIAN, HAN WAN, GUANG TAN. Cell cycle-related kinase in carcinogenesis. Oncology Letters 2012; 4(4) doi: 10.3892/ol.2012.828
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Maurizio Montella, Giovanni D’Arena, Anna Crispo, Mario Capunzo, Flavia Nocerino, Maria Grimaldi, Antonio Barbieri, Anna Maria D’Ursi, Mario Felice Tecce, Alfonso Amore, Massimiliano Galdiero, Gennaro Ciliberto, Aldo Giudice. Role of Sex Hormones in the Development and Progression of Hepatitis B Virus-Associated Hepatocellular Carcinoma. International Journal of Endocrinology 2015; 2015 doi: 10.1155/2015/854530
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Kimberly Cox-York, Evan Stoecker, Alison K. Hamm, Tiffany L. Weir. Microbiome and Cancer. Current Cancer Research 2019;  doi: 10.1007/978-3-030-04155-7_15
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Tong Liu, Wanchao Wang, Haozhe Cui, Miaomiao Sun, Yiming Wang, Xining Liu, Liying Cao, Hai Liu, Siqing Liu. Elevated fasting serum glucose levels increase the risk of hepatocellular carcinoma. Medicine 2019; 98(30) doi: 10.1097/MD.0000000000016369
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Cho Naing, Han Ni, Htar Htar Aung. Tamoxifen for adults with hepatocellular carcinoma. Cochrane Database of Systematic Reviews 2024; 2024(8) doi: 10.1002/14651858.CD014869.pub2
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Lulu Yu, Masahiko Ajiro, Vladimir Majerciak, Alexei Lobanov, Yafeng He, Maggie Cam, Baktiar Karim, Deanna Gotte, Chuxia Deng, Keji Zhao, Douglas R. Lowy, Nicholas J. G. Webster, Zhi-Ming Zheng. SRSF3 plays a key role in liver cancer sex disparity by facilitating hepatocyte expression of ERα and FOXA. Proceedings of the National Academy of Sciences 2026; 123(40) doi: 10.1073/pnas.2536317123
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Alison K. Buxton, Salma Abbasova, Charlotte L. Bevan, Damien A. Leach. Liver Microenvironment Response to Prostate Cancer Metastasis and Hormonal Therapy. Cancers 2022; 14(24) doi: 10.3390/cancers14246189
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Daniel Desaulniers, K. Leingartner, G. Pelletier, G.-H. Xiao, W. J. Bowers. Effects of Developmental Exposure to Mixtures of Environmental Contaminants on the Hepatic Metabolism of Estradiol-17β in Immature Female Sprague Dawley Rats. International Journal of Toxicology 2012; 31(5) doi: 10.1177/1091581812457431
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Yvonne G. J. van Helden, Roger W. L. Godschalk, Johannes von Lintig, Georg Lietz, Jean‐Francois Landrier, M. Luisa Bonet, Frederik J. van Schooten, Jaap Keijer. Gene expression response of mouse lung, liver and white adipose tissue to β‐carotene supplementation, knockout of Bcmo1 and sex. Molecular Nutrition & Food Research 2011; 55(10) doi: 10.1002/mnfr.201100194
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Sheng‐Han Wang, Pei‐Jer Chen, Shiou‐Hwei Yeh. Gender disparity in chronic hepatitisB: Mechanisms of sex hormones. Journal of Gastroenterology and Hepatology 2015; 30(8) doi: 10.1111/jgh.12934
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Yahong Xu, Yongjie Zhu, Zhenru Wu, Shengfu Li, Mingyang Shao, Qing Tao, Qing Xu, Yuwei Chen, Yuke Shu, Menglin Chen, Yongjie Zhou, Yujun Shi. Hepatocyte-specific HDAC3 ablation promotes hepatocellular carcinoma in females by suppressing Foxa1/2. BMC Cancer 2023; 23(1) doi: 10.1186/s12885-023-11393-1
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