Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Artif Intell Gastroenterol. Apr 30, 2024; 5(1): 90503
Published online Apr 30, 2024. doi: 10.35712/aig.v5.i1.90503
Evaluating the accuracy and reproducibility of ChatGPT-4 in answering patient questions related to small intestinal bacterial overgrowth
Lauren Schlussel, Jamil S Samaan, Yin Chan, Bianca Chang, Yee Hui Yeo, Wee Han Ng, Ali Rezaie
Lauren Schlussel, Jamil S Samaan, Yin Chan, Bianca Chang, Yee Hui Yeo, Ali Rezaie, Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States
Wee Han Ng, Bristol Medical School, University of Bristol, BS8 1TH, Bristol, United Kingdom
Ali Rezaie, Medically Associated Science and Technology Program, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States
Author contributions: Rezaie A was the guarantor, participated in the acquisition, analysis, and interpretation of the data, and revised the article for critically important intellectual content; Schlussel L drafted the initial manuscript and participated in the acquisition, analysis, and interpretation of the data; Samaan J designed the study and revised the article for critically important intellectual content; Chan Y and Chang B participated in the acquisition, analysis, and interpretation of the data, and revised the article for critically important intellectual content; Yeo YH revised the article for critically important intellectual content; Ng WH participated in the acquisition, analysis, and interpretation of the data.
Institutional review board statement: Our study did not require IRB approval, given our research does not involve human subjects.
Informed consent statement: Our research does not involve human subjects. Therefore, no signed informed consent or documents were obtained.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ali Rezaie, MD, MSc, FRCPC, Medical Director, Medically Associated Science and Technology Program, Cedars-Sinai Medical Center, Cedars-Sinai, 8730 Alden Drive, Thalians Bldg, #E240, Los Angeles, CA 90048, United States. Ali.rezaie@cshs.org
Received: December 7, 2023
Revised: March 27, 2024
Accepted: April 16, 2024
Published online: April 30, 2024
Core Tip

Core Tip: ChatGPT-4 demonstrates promise in enhancing patient understanding of basic concepts related to small intestinal bacterial overgrowth (SIBO). However, it exhibits limitations in accurately addressing questions about the diagnosis and treatment of SIBO, which are areas where up-to-date medical guidance is crucial. As such, artificial intelligence can be beneficial for general patient education but should not replace professional medical advice, especially for conditions with complex care protocols. Continuous refinement and updating of Chat-GPT’s knowledge are essential for its safe and effective application in healthcare. Rigorous scrutiny of artificial intelligence-generated content is imperative to prevent the dissemination of potentially harmful misinformation.