Metabolic and biological changes in children with obesity and diabetes

Table 3 Insulin, glucose/insulin, and homeostasis model assessment of insulin resistance levels during childhood

Group	Insulin	Glucose/insulin	HOMA-IR
Prepubertal
≤ 7.5 yr	2.9 (1.6-10.9)	29 (12-50)	0.6 (0.3-1.4)
> 7.5 yr	5 (1.7-9.6)	20 (10-47)	1.1 (0.3-2.0)
Pubertal
Girls	6.7 (1.8-16.9)	12 (7.9-44)	1.6 (0.3-2.6)
Boys	7.3 (2.2-12.9)	16 (8.0-44)	1.1 (0.3-2.4)

G/Ins: Glycemia/insulin ratio; HOMA-IR: Homeostasis model assessment of insulin resistance; Insulin level: μIU/mL: G/Ins ratio: G (mg/dL) and Ins (μIU/mL); HOMA-IR: Ins (μIU/mL) × G (mmol/L)/22.5.