Copyright
©The Author(s) 2021.
World J Meta-Anal. Feb 28, 2021; 9(1): 74-87
Published online Feb 28, 2021. doi: 10.13105/wjma.v9.i1.74
Published online Feb 28, 2021. doi: 10.13105/wjma.v9.i1.74
Table 4 Sensitivity analysis of efficacy and safety outcomes based on the risk of bias assessment and study design
| Variable | All studies | Sensitivity analysis(risk of bias assessment) | Sensitivity analysis (study design) | |||
| RR (95%CI) | I2 | RR (95%CI) | I2 | RR (95%CI) | I2 | |
| Mortality | 0.83 (0.57-1.20) | 59 | 0.83 (0.55-1.26) | 73 | 0.74 (0.38-1.44) | 65 |
| Ventilation | 0.69 (0.41-1.18) | 77 | 0.73 (0.42-1.27) | 83 | 0.57 (0.41-0.77) | 00 |
| Composite mortality and ventilation | 0.80 (0.58-1.11) | 78 | 0.83 (0.60-1.16) | 84 | 0.69 (0.55-0.86) | 10 |
| Clinical recovery | 1.10 (1.04-1.16) | 00 | 1.10 (1.02-1.18) | 00 | 1.10 (1.02-1.18) | 00 |
| Adverse event | 1.05 (0.86-1.27) | 77 | 0.94 (0.86-1.02) | 00 | 0.94 (0.86-1.02) | 00 |
| Grade 3 or 4 adverse event | 0.89 (0.80-0.99) | 00 | 0.87 (0.71-1.07) | 10 | 0.87 (0.71-1.07) | 10 |
| Serious adverse event | 0.75 (0.63-0.90) | 00 | 0.76 (0.64-0.92) | 00 | 0.76 (0.64-0.92) | 00 |
- Citation: Patel TK, Patel PB, Barvaliya M, Vijayalaxmi, Bhalla HL. Efficacy and safety outcomes with remdesivir in COVID-19 patients: A meta-analysis. World J Meta-Anal 2021; 9(1): 74-87
- URL: https://www.wjgnet.com/2308-3840/full/v9/i1/74.htm
- DOI: https://dx.doi.org/10.13105/wjma.v9.i1.74