Efficacy and safety outcomes with remdesivir in COVID-19 patients: A meta-analysis

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World Journal of Meta-Analysis

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2308-3840

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Meta-Analysis

World J Meta-Anal. Feb 28, 2021; 9(1): 74-87
Published online Feb 28, 2021. doi: 10.13105/wjma.v9.i1.74

Table 4 Sensitivity analysis of efficacy and safety outcomes based on the risk of bias assessment and study design

Variable	All studies		Sensitivity analysis(risk of bias assessment)		Sensitivity analysis (study design)
Variable	RR (95%CI)	I²	RR (95%CI)	I²	RR (95%CI)	I²
Mortality	0.83 (0.57-1.20)	59	0.83 (0.55-1.26)	73	0.74 (0.38-1.44)	65
Ventilation	0.69 (0.41-1.18)	77	0.73 (0.42-1.27)	83	0.57 (0.41-0.77)	00
Composite mortality and ventilation	0.80 (0.58-1.11)	78	0.83 (0.60-1.16)	84	0.69 (0.55-0.86)	10
Clinical recovery	1.10 (1.04-1.16)	00	1.10 (1.02-1.18)	00	1.10 (1.02-1.18)	00
Adverse event	1.05 (0.86-1.27)	77	0.94 (0.86-1.02)	00	0.94 (0.86-1.02)	00
Grade 3 or 4 adverse event	0.89 (0.80-0.99)	00	0.87 (0.71-1.07)	10	0.87 (0.71-1.07)	10
Serious adverse event	0.75 (0.63-0.90)	00	0.76 (0.64-0.92)	00	0.76 (0.64-0.92)	00

CI: Confidence interval; RR: Risk ratio.

Citation: Patel TK, Patel PB, Barvaliya M, Vijayalaxmi, Bhalla HL. Efficacy and safety outcomes with remdesivir in COVID-19 patients: A meta-analysis. World J Meta-Anal 2021; 9(1): 74-87
URL: https://www.wjgnet.com/2308-3840/full/v9/i1/74.htm
DOI: https://dx.doi.org/10.13105/wjma.v9.i1.74

Patel TK, Patel PB, Barvaliya M, Vijayalaxmi, Bhalla HL. Efficacy and safety outcomes with remdesivir in COVID-19 patients: A meta-analysis. World J Meta-Anal 2021; 9(1): 74-87 [DOI: 10.13105/wjma.v9.i1.74]

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