Inflammatory pseudotumor-like follicular dendritic cell sarcoma: Literature review of 67 cases

Table 2 Pathological features of inflammatory pseudotumor-like follicular dendritic cell sarcoma

Markers	Number of cases positive/number of cases tested	Cases positive, %
Necrosis	40/67	59.7
Hemorrhage	22/67	32.8
Granuloma	23/67	34.3
Fibrinoid deposits in blood vessel wall	22/67	32.8
CD1a	0/6	0
CD3	0/7	0
CD20	1/9	11.1
CD21	54/65	83.1
CD23	34/47	72.3
CD30	1/27	3.7
CD31	1/8	12.5
CD34	5/15	33.3
CD35	50/55	90.9
CD68	8/16	50
CD117	0/9	0
LMP1	28/34	82.4
EBER	60/63	95.2
D2-40	6/10	60
CNA.42	13/13	100
Clusterin	8/11	72.7
EGFR	3/8	37.5
Vimentin	6/6	100
CK-pan	0/9	0
Caldesmon	0/7	0
ALK1	0/42	0
Desmin	0/30	0
Fascin	9/9	100
SMA	32/39	82.1
MSA	5/9	55.5
EMA	2/8	25
S100	6/23	26.1
p53	1/6	16.7
HHV-8	0/7	0
TUBB3	3/6	50
γ-synuclein	2/6	33.3

EMA: Epithelial membrane antigen; HHV-8: Human herpes virus 8; LMP1: Latent membrane protein 1; MSA: Muscle-specific actin; SMA: Smooth muscle actin; TUBB3: Tubulin beta 3 class III.