Copyright
©The Author(s) 2020.
World J Meta-Anal. Oct 28, 2020; 8(5): 348-374
Published online Oct 28, 2020. doi: 10.13105/wjma.v8.i5.348
Published online Oct 28, 2020. doi: 10.13105/wjma.v8.i5.348
Table 5 Prevalence of hepatic abnormalities reported in different studies, n (%)
| Ref. | Location | Number of patients | AST elevation | ALT elevation | T. Bili elevation |
| Huang et al[42] | Wuhan, China | 41 | 15 (37) | NA | NA |
| Chen et al[1] | Wuhan, China | 99 | 35 (35) | 28 (28) | 18 (18) |
| Zhou et al[84] | Wuhan, China | 191 | NA | 59 (31) | NA |
| Chen et al[86] | Wuhan, China | 274 | 84 (31) | 60 (27) | NA |
| Xu et al[91] | Wuhan, China | 355 | 102 (28.7) | 91 (25.6) | 66 (18.6) |
| Huang et al[94] | Wuhan, China | 36 | 18 (58) | 4 (13.3) | 4 (12.9) |
| Shu et al[97] | Wuhan, China | 545 | 35 (10.1) | 41 (7.5) | 189 (34.7) |
| Cai et al[146] | Shenzhen City, Guangdong, China | 298 | 25 (8.4) | 39 (13.1) | 24 (8.1) |
| Ai et al[98] | Xiangyang, China | 102 | 26 (25.5) | 20 (19.6) | NA |
| Zhao et al[102] | Hefei, Anhui, China | 75 | 14 (18.7) | 15 (20) | 12 (16) |
| Zhao et al[100] | Beijing, China | 77 | 20 (26) | 26 (33.8) | NA |
| Qi et al[105] | Chongqing, China | 267 | 19 (7.1) | 20 (7.5) | 6 (2.2) |
| Lin et al[107] | Zhuhai, Guangdong, China | 95 | 4 (4.2) | 5 (5.3) | 22 (23.2) |
| Xu et al[109] | Multiple locations in China (All outside Hubei province) | 45 | NA | NA | NA |
| Yan et al[110] | Hainan Province, China | 168 | 18 (17.3) | 9 (8) | 7 (6.4) |
| Wang et al[111] | Zhengzhou, Henan, China | 18 | Abnormal LFTs 4 (25) | NA | |
| Chen et al[112] | Changsha and Loudi, Hunan, China | 291 | 44 (15.1) | 30 (10.3) | 27(9.3) |
| Yao et al[115] | Xi’an, Shaanxi, China | 40 | 16 (40) | 21 (52.5) | 10 (25) |
| Tian et al[116] | Liaocheng, Shandong, China | 37 | 4 (10.8) | 2 (5.4) | 13 (35.1) |
| Fu et al[120] | Kunming, Yunnan, China | 36 | 4 (11.1) | 4 (11.1) | 11 (30.56) |
| Xu et al[121] | Zhejiang, China | 62 | 10 (16.1) | NA | NA |
| Qian et al[122] | Multiple sites, Zhejiang, China | 91 | 9 (9.9) | 7 (7.7) | NA |
| Chen et al[123] | Multiple sites, Wenzhou, Zhejiang, China | 175 | 19 (11) | 23 (13) | NA |
| Guan et al[48] | Multiple sites across China | 1099 | 168 (22.2) | 158 (21.3) | 76 (10.5) |
| Ferm et al[77] | New York, United States | 892 | Borderline elevation (1-2 × ULN) 40% | Borderline elevation (1-2 × ULN) 26.5% | 4.3% |
| mild elevation (2-5 × ULN) 13.8% | mild elevation (2-5 × ULN) 11.5% | ||||
| moderate to severe elevation (> 5 × ULN) 2.8% | moderate to severe (> 5 × ULN) 1.9% | ||||
| Tabata et al[131] | Diamond Princess Cruise, Japan | 104 | 18 (17.3) | 17 (16.3) | NA |
- Citation: Pasha SB, Swi A, Hammoud GM. Gastrointestinal and hepatic manifestations of COVID-19 infection: Lessons for practitioners. World J Meta-Anal 2020; 8(5): 348-374
- URL: https://www.wjgnet.com/2308-3840/full/v8/i5/348.htm
- DOI: https://dx.doi.org/10.13105/wjma.v8.i5.348