Risk of infectious diseases and cutaneous tumours in solid organ recipients: A meta-analysis of literature

Table 2 Incidence of bacterial infections in solid organ recipients n (%)

Ref.	No. of cases/	Age (yr)	M/F	Median follow-	Therapy	Bacterial infections
	population			up time
Bakr et al[11]	302/Kidney	35.9 ± 11.3	216/86	0.25-23 yr	Miscellaneous	47 (16) Mainly folliculitis and impetigo
Hogewoning et al[15]	134/Kidney	32.6 ± 10.3	80/54	NA	NA	28 (20.9) Mainly folliculitis, ectyma and erysipelas (3)
Alangaden et al[66]	127/Liver	47 ± 12	79/62	NA	79% prednisone 72% tacrolimus 28% sirolimus	17 (13) Mainly wound infections and skin and soft tissue infections
Perera et al[21]	100/Liver	42.5	NA	5.5 (0.75-16) yr	35% cyclosporine, azathioprine and prednisone 48% prednisone and tacrolimus 17% tacrolimus	5 (5) Mainly folliculitis and 1 case of erythrasma
Sánchez-Lázaro et al[20]	604/Heart	51	506/98	First year after transplantation	NA	36 (5.9)
Savoia et al[65]	286/Kidney	NA	273/163	9.3 (0.1-39.8) yr	66.7% combination therapy comprising tacrolimus in 90%	6 (1.4) All cases of erysipelas
Lima et al[22]	53/Kidney	44	28/25	52.5% of patients over 5 yr	44% prednisone 31% mycophenolate	3 (5.7) 2 cases of furuncle and 1 cellulitis

For each literature study has been indicated number of included patients, type of solid organ transplantation, median age, sex, median follow-up time after solid organ transplantation, type of immunosuppressive treatment and the percentage of patients affected by bacterial infections; when available, type of bacterial infection has been specified. NA: Data non available in the considered study; M: Male; F: Female.