Endoscopic ultrasound-guided biliary drainage vs endoscopic retrograde cholangiopancreatography for malignant distal obstruction: Randomized-trial meta-analysis

doi:10.13105/wjma.124719

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World Journal of Meta-Analysis

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2308-3840

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Meta-Anal. Sep 18, 2026; 14(3): 124719
Published online Sep 18, 2026. doi: 10.13105/wjma.124719

Table 2 Summary of pooled outcomes

Outcome	EUS-guided	ERCP	RR (95%CI)	I²	Interpretation
Technical success	350/374	304/365	1.08 (0.96-1.22)	64	No clear difference; inconsistent
Clinical success	331/369	322/359	1.01 (0.95-1.07)	0	Comparable
Procedure-related adverse events	52/374	63/365	0.83 (0.53-1.31)	1	Imprecise
Postprocedural pancreatitis	2/374	24/365	0.20 (0.05-0.77)	0	Lower with ultrasound-guided drainage
Stent dysfunction or reintervention	35/374	56/365	0.60 (0.36-1.01)	0	Possible reduction; uncertain

Risk ratios use Paule-Mandel random effects and modified Hartung-Knapp confidence intervals. CI: Confidence interval; EUS: Endoscopic ultrasound; ERCP: Endoscopic retrograde cholangiopancreatography; RR: Risk ratio.

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Citation: Salman A, Salman MA, Shaaban HE. Endoscopic ultrasound-guided biliary drainage vs endoscopic retrograde cholangiopancreatography for malignant distal obstruction: Randomized-trial meta-analysis. World J Meta-Anal 2026; 14(3): 124719
URL: https://www.wjgnet.com/2308-3840/full/v14/i3/124719.htm
DOI: https://dx.doi.org/10.13105/wjma.124719

Salman A, Salman MA, Shaaban HE. Endoscopic ultrasound-guided biliary drainage vs endoscopic retrograde cholangiopancreatography for malignant distal obstruction: Randomized-trial meta-analysis. World J Meta-Anal 2026; 14(3): 124719 [DOI: 10.13105/wjma.124719]

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