Safety and efficacy of dexmedetomidine for flexible bronchoscopy: A systematic review and meta-analysis

doi:10.13105/wjma.v14.i1.112793

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World Journal of Meta-Analysis

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2308-3840

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Meta-Anal. Mar 18, 2026; 14(1): 112793
Published online Mar 18, 2026. doi: 10.13105/wjma.v14.i1.112793

Table 2 Baseline patient characteristics, mean ± SD/ mean (95%CI)

Ref.	Age (year)		Weight (kg)			Body mass index (kg/m²)			Duration of bronchoscopy		Heart rate (bpm)		Mean systolic blood pressure (mmHg)		Mean diastolic blood pressure (mmHg)		Mean oxygen saturation, saturation of oxygen in blood
Ref.	Intervention	Control	Intervention	Control		Intervention	Control		Intervention	Control	Intervention	Control	Intervention	Control	Intervention	Control	Intervention	Control
Magazine et al[27], 2024	47.65 ± 13.41	50.23 ± 11.97	52.94 ± 12.36	57.16 ± 10.95		20.90 ± 4.86	21.83 ± 3.19		15.35 ± 11.93	12.84 ± 8.11	89.87 ± 11.35	85.94 ± 16.86	133.77 ± 22.38	124.68 ± 14.16	83.29 ± 8.77	76.61 ± 9.31	99.45 ± 1.50	99.23 ± 1.28
Magazine et al[28], 2021	48.50 ± 13.138	44.42 ± 12.047	50.55 ± 10.20	50.07 ± 7.81		20.25 ± 2.80	20.05 ± 3.36		13.42 ± 6.801	10.54 ± 3.706	81.92 ± 18.533	84.83 ± 15.670	127.42 ± 20.930	126.58 ± 20.905	74.08 ± 11.088	78.92 ± 9.528	99.92 ± 0.408	100.00 ± 0.000
Kim et al[29], 2021	63.7 ± 11.3	63.9 ± 11.0	-	-		23.4 ± 2.9	23.7 ± 2.6		-	-	-	-	-	-	-	-	-	-
Zhang et al[31], 2021	58.03 ± 14.04	60.23 ± 11.56	63.40 ± 11.60	61.76 ± 9.72		-	-		24.40 ± 12.37	20.29 ± 10.96	-	-	-	-	-	-	-	-
Magazine et al[30], 2020	47.07 ± 13.40	45.00 ± 14.26	53.23 ± 8.69	50.37 ± 9.84		20.61 ± 3.27	19.98 ± 3.51		-	-	87.85 ± 16.19	87.41 ± 16.31	131.63 ± 22.56	126.67 ± 18.92	77.85 ± 9.53	77.19 ± 11.49	100.00 ± 0	99.85 ± 0.53
Goneppanavar et al[32], 2015	49.70 ± 13.85	52.52 ± 15.05	53.26 ± 10.10	56.07 ± 10.84		20.77 ± 3.40	20.42 ± 3.46		8.93 ± 2.96	8.19 ± 2.53	-	-	-	-	-	-	-	-
Liao et al[33], 2012	58.5 ± 9.1	60.1 ± 8.4	57.0 ± 8.4	58.2 ± 11.3		-	-		12.8 ± 2.6	13.1 ± 2.6	-	-	-	-	-	-	-	-
Kumari et al[34], 2021	44 ± 14	49 ± 14	63 ± 13	65 ± 13		-	-		-	-	-	-	-	-	-	-	-	-
Zhou et al[21], 2024	61 (55-65)	60 (52-66)	60 (53-68)	61 (54-70)		22.24 ± 2.787	22.60 ± 2.742		13 (10-18.5)	13 (10-19)	-	-	-	-	-	-	-	-
Riachy et al[22], 2018	63		-	-		-	-		16		-	-	-	-	-	-	-	-
Yuan et al[23], 2016	59.76 ± 7.61	60.46 ± 69.3	-	-		22.20 ± 3.06	21.69 ± 3.16		20.64 ± 2.08	21.14 ± 1.87	-	-	-	-	-	-	-	-
Shoukry et al[24], 2016	50.3 ± 14.9	47.9 ± 15.3	77.9 ± 14.2	80.3 ± 14.0		-	-		21.8 ± 3.9	21.5 ± 3.6	-	-	-	-	-	-	-	-
Mani et al[26], 2015	-	-	164.9			61.3 ± 6.15			-	-	-	-	-	-	-	-	-	-
Ryu et al[25], 2012	52.9 (27-67)	52.9 (23-69)	62.1 ± 13.8		60.6 ± 13.8	-		-	12.1 ± 2.8	12.0 ± 3.4	-	-	-	-	-	-	-	-

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Citation: Hassni A, Siddiqui AH, Shahid M, Shariq A, Anwar H, Nadeem K, Anjum A, Memon H, Talha A, Khan S, Faisal Y, Naveed M, Moeed A, Surani S. Safety and efficacy of dexmedetomidine for flexible bronchoscopy: A systematic review and meta-analysis. World J Meta-Anal 2026; 14(1): 112793
URL: https://www.wjgnet.com/2308-3840/full/v14/i1/112793.htm
DOI: https://dx.doi.org/10.13105/wjma.v14.i1.112793

Hassni A, Siddiqui AH, Shahid M, Shariq A, Anwar H, Nadeem K, Anjum A, Memon H, Talha A, Khan S, Faisal Y, Naveed M, Moeed A, Surani S. Safety and efficacy of dexmedetomidine for flexible bronchoscopy: A systematic review and meta-analysis. World J Meta-Anal 2026; 14(1): 112793 [DOI: 10.13105/wjma.v14.i1.112793]

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