Retrospective Study
Copyright ©The Author(s) 2020.
World J Clin Cases. Mar 26, 2020; 8(6): 1065-1073
Published online Mar 26, 2020. doi: 10.12998/wjcc.v8.i6.1065
Table 2 Response to treatment with ruxolitinib
ParameteraGVHD, n = 10cGVHD, n = 28
Overall response rate, n (%)10 (100)22 (82.1)
Median follow-up time in mo, median (range)2.5 (1.5–4)5 (1.5–10)
Time to best overall response in mo, median (range)1.0 (0.5–2.5)3.0 (1.0–9.5)
Time to best response for each organ system in d, median (range)
Skin28 (14–28)77 (7–147)
Digestive tract25 (14–60)259 (70–308)
Liver32 (21–42)42 (28–56)
Eye-112 (42–182)
Oral cavity-80 (28–168)
Lung-91 (49–140)
Fascia-91 (56–266)
Discontinuation of immunosuppressive agents after ruxolitinib, n (%)8 (80.0)21 (75.0)