Successful treatment of basaloid squamous cell carcinoma in the rectosigmoid colon: A case report and review of literature

Table 1 Previous basaloid squamous cell carcinoma in the colorectum (review of the literature)

Ref.	Age/gender	Tumor location	Tumor size, cm	Operation methods	Depth of invasion	Lymph node metastasis	Systemic metastasis	Treatment after surgery	Survival, mo	Immune positive	Immune negative
Strate et al[7], 1977	59/F	Sigmoid	7 × 1.5	palliating colectomy, colostomy	Subserosa	Yes	Liver	NA	0	PTH, ACTH	NA
Hall-Craggs et al[8], 1982	69/F	Sigmoid	4 × 2	excised colon	Serosa	No	Liver	NA	NA	NA	NA
Indinnimeo et al[9], 1998	61/F	Rectum	6 × 5 × 7	APR	Serosa	No	No	Radiotherapy Chemotherapy (cisplatin plus 5-FU)	19	ki67, CD31	NA
Newell et al[5], 2001	54/M	Splenic flexure	10	palliative resection	Serosa	Yes	Liver	NA	0.3	Low/high-molecular weight keratin, CK 5/6, EMA, NSE	CK 7, CK 20, CEA, vimentin, desmin, SMA, chromogranin, synaptophysin, serotonin, PTH, ACTH, calcitonin, gastrin, glucagon, VIP, PP, CD34, somatostatin
Garcia-higuera et al[12], 2002	67/M	Recto-sigmoid	3.5 × 3.2	Anterior resection	Serosa	Yes	Liver, lung	Radiotherapy Chemotherapy (cisplatin plus 5-FU)	6	NA	NA
Jaswal et al[13], 2002	24/F	Descending colon	3 × 2.5	Left hemicolectomy	Serosa	Yes	Liver, para-aortic and iliac lymph nodes	NA	3	NA	NA
Akbulut et al[10], 2009	23/M	Recto-sigmoid	8 × 8.5	Hartmann`s operation	Serosa	NA	NA	Radiotherapy Chemotherapy (irinotecan)	5	High-molecular weight keratin, p63	NA
Ha et al[14], 2013	70/M	Recto-sigmoid	6.0 × 7.0	Low anterior resection	Serosa	NA	Liver, lung	NA	Loss the follow up	NA	NA
Gurzu et al[11], 2014	61/F	Sigmoid	3.5 × 2.5	Anterior resection	Subserosa	No	Liver	Chemotherapy (FOLFOX plus bevacizumab)	4	Pan-CK, CK 5/6, EMA, NSE, bcl-2, VEGF, CD105, p53	CK 7, CK 20, CEA, chromogranin, p63, c-KIT, maspin
Our case	58/F	Recto-sigmoid	10 × 4 × 4	Low anterior resection, PLND, diverting ileostomy, TAH with BSO	Serosa	No	No	Chemotherapy (Mitomycin C plus 5-FU)	96	CK7, p63, Pan-CK	CK20, CD34. CD117, Vimentin, CD56, WT-1, Calretinin, SMA, CD99, Synaptophysin, TTF-1, CDX2, desmin. S-100 protein

LN: Lymph node; APR: Abdominoperineal resection; PLND: Pelvic lymph node dissection; TAH: Transabdominal hysterectomy; BSO: Bilateral salphingo-oophorectomy; 5-FU: 5-fluorouracil; FOLFOX: Oxaliplatin with 5-fluorouracil and folinic acid; EMA: Epithelial membrane antigen; NSE: Neuron specific enolase; PTH: Parathyroid hormone; ACTH: Adrenocorticotropic hormone; CEA: Carcinoembryonic antigen; SMA: Smooth muscle antigen; PTH: Parathyroid hormone; VIP: Vasoactive intestinal peptide; PP: Pancreatic polypeptide; VEGF: Vascular endothelial growth factor; WT-1: Wilms' tumor protein; TTF-1: Thyroid transcription factor 1; CDX2: Caudal type homeobox 2; NA: Not available.