Prognostic factors for overall survival in prostate cancer patients with different site-specific visceral metastases: A study of 1358 patients

doi:10.12998/wjcc.v8.i1.54

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Retrospective Study

World J Clin Cases. Jan 6, 2020; 8(1): 54-67
Published online Jan 6, 2020. doi: 10.12998/wjcc.v8.i1.54

Table 7 Multivariable Cox regression analysis of prognostic factors affecting overall survival in prostate cancer patients with lung, brain, and liver metastases

Variable	Lung			Brain			Liver
Variable	HR	95%CI	P value	HR	95%CI	P value	HR	95%CI	P value
Age (yr)
≤ 70	Ref.			Ref.			Ref.
> 70	2.084	1.601-2.712	< 0.001	0.994	0.553-1.785	0.983	1.499	1.099-2.043	0.010
Grade¹
I/II	Ref.
III/IV	2.031	0.879-4.692	0.097
Unknown	NA	NA	NA
T stage
T1/T2	Ref.			Ref.			Ref.
T3/T4	1.490	1.135-1.958	0.004	1.785	1.007-3.163	0.047	1.021	0.737-1.414	0.900
Unknown	NA	NA	NA	NA	NA	NA	NA	NA	NA
Gleason score
≤ 8	Ref.						Ref.
> 8	1.735	1.315-2.289	< 0.001				1.688	1.224-2.327	0.001
Unknown	NA	NA	NA				NA	NA	NA
Bone metastases
No	Ref.
Yes	1.327	0.961-1.833	0.086
Unknown	NA	NA	NA

¹I: Well differentiated; II: Moderately differentiated; III: Poorly differentiated; IV: Undifferentiated. All variables with Unknown Data did not fit in Cox and Kaplan–Meier model. NA: Not available; PSA: Prostate-specific antigen.

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Citation: Cui PF, Cong XF, Gao F, Yin JX, Niu ZR, Zhao SC, Liu ZL. Prognostic factors for overall survival in prostate cancer patients with different site-specific visceral metastases: A study of 1358 patients. World J Clin Cases 2020; 8(1): 54-67
URL: https://www.wjgnet.com/2307-8960/full/v8/i1/54.htm
DOI: https://dx.doi.org/10.12998/wjcc.v8.i1.54

Cui PF, Cong XF, Gao F, Yin JX, Niu ZR, Zhao SC, Liu ZL. Prognostic factors for overall survival in prostate cancer patients with different site-specific visceral metastases: A study of 1358 patients. World J Clin Cases 2020; 8(1): 54-67 [PMID: 31970170 DOI: 10.12998/wjcc.v8.i1.54]

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