Interaction of arylsulfatases A and B with maspin: A possible explanation for dysregulation of tumor cell metabolism and invasive potential of colorectal cancer

Table 3 Correlation between arylsulfatase B expression and pathological aspects of colorectal cancer

Characteristics	Number	ARSB expression		P value
		Low	High
Age, yr
≤ 60	19	7	12	0.091
> 60	26	4	22
Gender
Male	26	5	21	0.341
Female	19	6	13
Macroscopic aspect
Polypoid	12	7	5	0.0031
Ulcero-infiltrative	33	4	29
Microscopic aspect
G1	14	2	12	0.0072
G2	24	4	20
G3+4	7	5	2
Localization
Proximal	8	2	6	0.992
Distal	21	5	16
Upper rectum	16	4	12
Lymph node ratio
< 0.1	34	9	25	0.701
≥ 0.1	11	2	9
Lymph node metastasis
Absent	29	9	20	0.271
Present	16	2	14
pT stage
≤ T2	15	5	10	0.461
≥ T3	30	6	23
Budding grade
G1	15	3	12	0.822
G2	9	2	7
G3	21	6	15
Maspin expression
Positive	22	2	20	0.03
Negative	23	9	14

¹Fisher’s exact test.

²χ² test. Significant differences are shown in bold. G1: Well differentiated; G2: Moderately differentiated; G3: Poorly differentiated, 4 mucinous.