Mycobacterium chimaera infections following cardiac surgery in Treviso Hospital, Italy, from 2016 to 2019: Cases report

Table 3 Microbiological features

Case	Specimens	Time for cultural identification	Other positive tests	Antimicrobial susceptibility test
11	Sputum	8 wk		Macrolid (S)2
	Broncholavage	10 wk
	Bioprosthesis	np	PCR
	Pericardial abscess	8 wk
	Blood	np
2	Blood	4 wk		Macrolid (S)2
3	Blood	4 wk		Macrolid (S)2
4	Blood (2)	3 wk		Clarithromycin (S); Linezolid (R); Moxifloxacin (S); Aminoglycoside (S)2; Macrolid (S)2
	Bioprosthesis	6 wk	Microscopy after enrichment
	Vertebral bone	12 wk
5	Vertebral bone (3)	3, 5, and 10 wk	Auramine rhodamine stain	Clarithromycin (S); Linezolid (I); Moxifloxacin (R)
	Blood (2)	Negative
6	Blood (3)	3, 4, and 5 wk		Clarithromycin (S); Linezolid (I); Moxifloxacin (R)
	Bone Marrow	2 wk	Microscopy after enrichment
	Bioprosthesis (5)	3 wk	Microscopy after enrichment
7	Blood	6 wk		Clarithromycin (S); Linezolid (I); Moxifloxacin (S)
8	Blood (2)	4 wk		Clarithromycin (S); Linezolid (S); Moxifloxacin (S)
9	Blood	4 wk		ip

¹Originally identified as M. intracellulare;

²Molecular Characterization. ip: In process; np: Not performed; S: Susceptible; I: Intermediate; R: Resistant.