Sinusoidal obstruction syndrome: A systematic review of etiologies, clinical symptoms, and magnetic resonance imaging features

Table 5 Clinical characteristics of 13 patients in 11 case reports, n (%)

Variable	No. of patients with available data	Value
Sex (male/female)	13	7/6
Age, yr	13	47.9
Underlying disease
None	13	4 (30.8)
Postoperative liver metastasis of advanced colorectal cancer	13	3 (23.1)
Leukemia	13	2 (15.4)
Liver cirrhosis	13	1 (7.7)
Hepatic metastasis of colonic carcinoma	13	1 (7.7)
Gastric adenocarcinoma	13	1 (7.7)
Clinical symptom
Ascites	13	7 (53.8)
Abdominal swelling	13	4 (30.8)
Pleural effusion	13	4 (30.8)
Hepatomegaly	13	3 (23.1)
Jaundice	13	3 (23.1)
Stomach ache	13	3 (23.1)
Weak	13	3 (23.1)
Lower limbs edema	13	2 (15.4)
Lower limbs lassitude	13	2 (15.4)
Loss of appetite	13	2 (15.4)
Yellow urine	13	2 (15.4)
Oliguria	13	1 (7.7)
Esophageal varices	13	1 (7.7)
PVH	13	1 (7.7)
Etiology
Chemotherapy	13	5 (38.5)
Tusanqi	13	4 (30.8)
Hematopoietic stem cell transplantation	13	2 (15.4)
“Poppers,” a recreational drug used during anal intercourse	13	1 (7.7)
Drug toxicity (6-thioguanine)	13	1 (7.7)
Laboratory index
ALP, U/L	11	206.4
ALT, U/L	9	836.2
AST, U/L	8	1284.25
GGT, U/L	7	155.42
LDH, U/L	3	5608.33
TBil, μmol/L	9	63.11
DBil, μmol/L	5	35
Alb, g/L	5	37.52
TBA, g/L	2	27.65
T-CHE, U/L	2	3242
TP, g/L	1	47.7
CA-125, U/mL	1	299.1

PVH: Portal hypertension; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; GGT: Gamma-glutamyl transpeptidase; TBil: Total bilirubin; DBil: Direct bilirubin; prothrombin time; ALB: Albumin; TBA: Total bile acid.