Performance of common imaging techniques vs serum biomarkers in assessing fibrosis in patients with chronic hepatitis B: A systematic review and meta-analysis

doi:10.12998/wjcc.v7.i15.2022

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

World J Clin Cases. Aug 6, 2019; 7(15): 2022-2037
Published online Aug 6, 2019. doi: 10.12998/wjcc.v7.i15.2022

Table 1 Meta-analysis of hepatitis B-related significant fibrosis

	SEN (95%CI)	SPE (95%CI)	DOR (95%CI)
APRI	0.69 (0.63-0.73)	0.71 (0.66-0.75)	5 (4-6)
FIB-4	0.62 (0.57-0.67)	0.75 (0.71-0.78)	5 (4-5)
ARFI	0.77 (0.70-0.83)	0.87 (0.81-0.92)	23 (15-38)
FibroScan	0.72 (0.68-0.76)	0.82 (0.77-0.86)	12 (9-16)
MRE	0.94 (0.91-0.96)	0.96 (0.93-0.97)	348 (185-656)

SEN: Sensitivity; SPE: Specificity; DOR: Diagnostic odds ratio; CI: Confidence interval; APRI: Aminotransferase-to-platelet ratio index; FIB-4: Fibrosis index based on the 4 factors; ARFI: Acoustic radiation force impulse.

Citation: Xu XY, Wang WS, Zhang QM, Li JL, Sun JB, Qin TT, Liu HB. Performance of common imaging techniques vs serum biomarkers in assessing fibrosis in patients with chronic hepatitis B: A systematic review and meta-analysis. World J Clin Cases 2019; 7(15): 2022-2037
URL: https://www.wjgnet.com/2307-8960/full/v7/i15/2022.htm
DOI: https://dx.doi.org/10.12998/wjcc.v7.i15.2022