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Oct 16, 2025 (publication date) through Sep 3, 2025
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World Journal of Clinical Cases
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2307-8960
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Systematic Reviews
Copyright ©The Author(s) 2025.
World J Clin Cases. Oct 16, 2025; 13(29): 111096
Published online Oct 16, 2025. doi: 10.12998/wjcc.v13.i29.111096
Table 7 Summary of clinical strategies for preventing gestational diabetes mellitus recurrence
Strategy
Effectiveness
Comments
Preconception lifestyle++Strongest evidence, cost-effective
Mid-late pregnancy lifestyle-Typically implemented too late for meaningful metabolic benefit
Metformin-No proven preventive effect
Probiotics-Promising but inconsistent
Bariatric surgery+++Consider for BMI ≥ 35 kg/m² and failed lifestyle efforts
Effectiveness ratings are qualitative (+ to +++), based on current clinical trial data and expert consensus. BMI: Body mass index.
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