Systematic Reviews
Copyright ©The Author(s) 2025.
World J Clin Cases. Oct 16, 2025; 13(29): 108046
Published online Oct 16, 2025. doi: 10.12998/wjcc.v13.i29.108046
Table 2 Gross histology of the external ocular tunic
Histologic landmarks
Structural anatomy
Clinical anatomy
EpiscleraLoose fibroelastic tissue layer overlying Tenon's capsuleVascularized portion of sclera
Tenon’s capsuleSmooth muscle fiber and collagenous fasciaTransition zone from episclera to sclera
StromaInterlacing network of type 1 collagen and elastic fibers, oriented without parallelism. Dense portion of sclera
Suprachoroidal laminaContains fibroblasts and melanocytesThin fibrous connective tissue between sclera and choroid
Scleral endotheliumSimple squamous epitheliumCovers deep suprachoroidal lamina at the limbus
LimbusScleral-corneal junction. Transition of scleral to corneal collagen bundlesArea of contact between conjunctival stroma and Tenon's capsule. Limbal stem cells (unipotent to superficial corneal layers) at palisades of Vogt