Exploring macrophage polarization as a prognostic indicator for colorectal cancer: Unveiling the impact of metalloproteinase mutations

Table 4 MANOVA analysis of macrophages CD163, iNOS e CD206 combined (n = 61)

	Degrees of freedom	F	Hotelling-Lawley test	P value
Instability	1	0.314	0.005	0.958
Age	1	0.537	0.028	0.659
Location	1	0.058	0.003	0.936
Staging	3	1.697	0.296	0.094
Recurrence	1	0.650	0.038	0.586
Clinical outcome	1	1.929	0.102	0.305
Instability vs location	1	1.061	0.006	0.322
Instability vs clinical outcome	1	2.592	0.141	0.019