Exploring macrophage polarization as a prognostic indicator for colorectal cancer: Unveiling the impact of metalloproteinase mutations

Table 2 Variable analysis regarding staging (n = 61)

	Total		Stage I, n = 10		Stage II, n = 19		Stage III, n = 25		Stage IV, n = 5		P value
	n	%	n	%	n	%	n	%	n	%
Instability											0.05a
No mutation	33	52.5	3	30.0	8	40.0	18	72.0	4	66.66
With mutation	28	47.5	7	70.0	12	60.0	7	28.0	2	33.33
Age (year)											0.61
≤ 60	15	24.6	1	10.0	6	30.0	7	28.0	1	16.7
> 60	46	75.4	9	90.0	14	70.0	18	72.0	5	83.3
Sex											0.055
Female	43	70.5	9	90.0	17	85.0	14	56.0	3	50.0
Male	18	29.5	1	10.0	3	15.0	11	44.0	3	50.0
Location											0.722
Right colon	44	72.1	8	80.0	16	80.0	17	68.0	3	50.0
Left colon	17	27.9	2	20.0	4	20.0	8	32.0	3	50.0
Colectomy											0.342
Right side	39	63.9	7	70.0	15	75.0	14	56.0	3	50.0
Left side	15	24.6	3	30.0	3	15.0	6	24.0	3	50.0
Total	7	11.5	0	0.0	2	10.0	5	20.0	0	0.0
Lymphocytes											0.874
Low	30	50.0	3	33.3	10	50.0	14	56.0	3	50.0
Moderate	18	30.0	4	44.4	6	30.0	7	28.0	1	16.6
Intense	12	20.0	2	22.2	4	20.0	4	16.0	2	33.3
Recurrence											0.59
No	49	87.5	9	100.0	16	89.0	19	82.6	5	83.3
Yes	7	12.5	0	0.0	2	11.0	4	17.4	1	16.7
Clinical outcome											0.022a
Disease-free	49	80.3	8	80.0	17	85.0	22	88.0	2	33.3
Death	12	19.7	1	10.0	3	15.0	3	12.0	4	66.6

^aStatistically significant.

Qualitative variables expressed in values of absolute frequency and relative frequency.

The percentual value shown as relative frequency is taking into account the percentage of valid cases, that is, excluding the missing values.