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©The Author(s) 2025.
World J Clin Cases. Aug 16, 2025; 13(23): 105011
Published online Aug 16, 2025. doi: 10.12998/wjcc.v13.i23.105011
Published online Aug 16, 2025. doi: 10.12998/wjcc.v13.i23.105011
Table 1 Variable analysis regarding microsatellite instability (n = 61)
Total | No mutation, n = 33 | With mutation, n = 28 | P value | ||||
n | % | n | % | n | % | ||
Age (year) | 0.1351 | ||||||
≤ 60 | 15 | 24.6 | 11 | 33.3 | 4 | 14.3 | |
> 60 | 46 | 75.4 | 22 | 66.7 | 24 | 85.7 | |
Sex | 0.0931 | ||||||
Female | 43 | 70.5 | 20 | 60.6 | 23 | 82.1 | |
Male | 18 | 29.5 | 13 | 39.4 | 5 | 17.9 | |
Location | 0.1541 | ||||||
Right colon | 44 | 72.1 | 21 | 54.5 | 23 | 78.6 | |
Left colon | 17 | 27.9 | 12 | 45.5 | 5 | 21.4 | |
Staging | 0.051 | ||||||
I | 10 | 16.9 | 3 | 9.7 | 7 | 25.0 | |
II | 19 | 32.2 | 7 | 22.6 | 12 | 42.9 | |
III | 25 | 42.4 | 18 | 58.0 | 7 | 25 | |
IV | 5 | 8.5 | 3 | 9.7 | 2 | 7.1 | |
Colectomy | 0.248 | ||||||
Right side | 39 | 63.9 | 18 | 54.5 | 21 | 75.0 | |
Left side | 15 | 24.6 | 10 | 30.3 | 5 | 17.9 | |
Total | 7 | 11.5 | 5 | 15.2 | 2 | 7.1 | |
Lymphocytes | 0.24 | ||||||
Low | 30 | 50.0 | 18 | 54.6 | 12 | 44.4 | |
Moderate | 18 | 30.0 | 7 | 21.2 | 11 | 40.7 | |
Intense | 12 | 20.0 | 8 | 24.2 | 4 | 14.9 | |
Reccurence | 0.4431 | ||||||
No | 49 | 87.5 | 26 | 83.9 | 23 | 92.0 | |
Yes | 7 | 12.5 | 5 | 16.1 | 2 | 8.0 | |
Clinical outcome | 1.01 | ||||||
Disease-free | 49 | 80.3 | 26 | 78.8 | 23 | 82.1 | |
Death | 12 | 19.7 | 7 | 21.2 | 5 | 17.9 |
- Citation: Brambilla E, Brambilla DJF, Tregnago AC, Riva F, Pasqualotto FF, Soldera J. Exploring macrophage polarization as a prognostic indicator for colorectal cancer: Unveiling the impact of metalloproteinase mutations. World J Clin Cases 2025; 13(23): 105011
- URL: https://www.wjgnet.com/2307-8960/full/v13/i23/105011.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v13.i23.105011