Multinucleated giant cells of bladder mucosa are modified telocytes: Diagnostic and immunohistochemistry algorithm and relation to PD-L1 expression score

doi:10.12998/wjcc.v11.i26.6091

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Sep 16, 2023; 11(26): 6091-6104
Published online Sep 16, 2023. doi: 10.12998/wjcc.v11.i26.6091

Table 2 Immunohistochemical-phenotype of multinucleated giant cells in the stroma of the urothelial carcinoma and the surrounding vesical lamina propria

IHC antibodies	Expression
VIMENTIN	+
SMA	+
DESMIN	+
CD34	+
CD68	+
P16	+
CK AE1/AE3	-
CD31	-
PS100	-
C-KIT (CD117)	-
CD34BLAST	-
KI-67	-
IGG	-
PD-L1	-
GATA3	-
CD10	-
CD45	-
CD1A	-

IHC: Immunohistochemical.

Citation: Gulinac M, Velikova T, Dikov D. Multinucleated giant cells of bladder mucosa are modified telocytes: Diagnostic and immunohistochemistry algorithm and relation to PD-L1 expression score. World J Clin Cases 2023; 11(26): 6091-6104
URL: https://www.wjgnet.com/2307-8960/full/v11/i26/6091.htm
DOI: https://dx.doi.org/10.12998/wjcc.v11.i26.6091