Idiopathic membranous nephropathy in children: A case report

Table 3 Differences between idiopathic membranous nephropathy and minimal change disease in children

		IMN	MCD
General features	Sex	Male	Male
	Age	Adolescence	Preschool age
Clinical manifestations	Nephrotic syndrome	Common	Common
	Leukocyturia	Some	Rare
	Hematuria	Some	Rare
	Hypertension	Some	Rare
	Renal failure	Some	Rare
Laboratory tests	Anti-PLA2R, antibody	Elevated	Normal
	Anti-THSD7A, antibody	Elevated	Normal
Treatment strategy	Prednisone	Mostly resistance	Mostly sensitive
	Immunosuppressant	Tacrolimus, cyclophosphamide, mycophenolate mofetil	Rare
	Biological agent	Rituximab	Rare

PLA₂R: Phospholipase A₂ receptor; THSD7A: Thrombospondin type-1 domain-containing 7A; IMN: Idiopathic membranous nephropathy; MCD: Minimal change disease.