Case Control Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 6, 2021; 9(34): 10464-10471
Published online Dec 6, 2021. doi: 10.12998/wjcc.v9.i34.10464
Effect of Nephritis Rehabilitation Tablets combined with tacrolimus in treatment of idiopathic membranous nephropathy
Wei Lv, Mei-Rong Wang, Cheng-Zhen Zhang, Xue-Xu Sun, Zhen-Zhen Yan, Xiao-Min Hu, Tao-Tao Wang
Wei Lv, Cheng-Zhen Zhang, Xue-Xu Sun, Tao-Tao Wang, Department of Nephology, China People’s Liberation Army 32298, Weifang 261000, Shandong Province, China
Mei-Rong Wang, Department of Pharmacy, China People’s Liberation Army 32298, Weifang 261000, Shandong Province, China
Zhen-Zhen Yan, Xiao-Min Hu, Department of Blood Purification, China People’s Liberation Army 32298, Weifang 261000, Shandong Province, China
Author contributions: Lv W, Wang MR, and Wang TT designed this study; Lv W, Wang MR, and Zhang CZ wrote this paper; Lv W, Wang MR, Zhang CZ, Sun XX, Yan ZZ, and Hu XM were responsible for sorting the data.
Institutional review board statement: The study was reviewed and approved by the Hospital of No. 80 Group Army Institutional Review Board (Approval No. 63).
Informed consent statement: All patients gave informed consent.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
Data sharing statement: No additional data are available.
STROBE statement: The manuscript was checked and revised according to the STROBE Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tao-Tao Wang, BMed, Attending Doctor, Department of Nephology, China People’s Liberation Army 32298, No. 256 North Palace West Street, Weicheng District, Weifang 261000, Shandong Province, China. 187254754@qq.com
Received: July 19, 2021
Peer-review started: July 19, 2021
First decision: August 19, 2021
Revised: August 22, 2021
Accepted: October 12, 2021
Article in press: October 12, 2021
Published online: December 6, 2021
Core Tip

Core Tip: Generally, Nephritis Rehabilitation Tablets combined with tacrolimus in the treatment of idiopathic membranous nephropathy can effectively improve the renal function of patients and downregulate the expression of urinary IgG4 and C5b-9. In addition, they can help to improve the overall treatment effect while not increasing the risk of adverse reactions.