Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 26, 2021; 9(33): 10300-10307
Published online Nov 26, 2021. doi: 10.12998/wjcc.v9.i33.10300
Extracranial multiorgan metastasis from primary glioblastoma: A case report
Xing-Zhao Luan, Hao-Run Wang, Wei Xiang, Shen-Jie Li, Haiping He, Li-Gang Chen, Jian-Mei Wang, Jie Zhou
Xing-Zhao Luan, Hao-Run Wang, Wei Xiang, Shen-Jie Li, Haiping He, Li-Gang Chen, Jie Zhou, Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
Xing-Zhao Luan, Hao-Run Wang, Wei Xiang, Shen-Jie Li, Haiping He, Li-Gang Chen, Jie Zhou, Sichuan Clinical Research Center for Neurosurgery, Southwest Medical University, Luzhou 646000, Sichuan Province, China
Hao-Run Wang, Wei Xiang, Shen-Jie Li, Haiping He, Li-Gang Chen, Jie Zhou, Academician (Expert) Workstation of Sichuan Province, Southwest Medical University, Luzhou 646000, Sichuan Province, China
Jian-Mei Wang, Department of Pathology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
Author contributions: Luan XZ conceptualized and drafted the report; Wang HR was responsible for the imaging curation; Li SJ was responsible for the methodology; Xiang W conceptualized and revised the manuscript; He HP collected patient data; Wang JM conducted and supervised the pathological examinations; Chen LG supervised the study; Zhou J supervised the study, reviewed and edited the manuscript; all authors issued final approval for the version to be submitted.
Supported by Medical Research Fund for Young Scholars of the Sichuan Medical Association, No. Q16076; Natural Science Foundation of Southwest Medical University, No. 2016XNYD217; and Science and Technology Projects of Sichuan Province, No. 2018JY0403.
Informed consent statement: Informed written consent was obtained from the patient and legal guardian for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jie Zhou, MD, Associate Chief Physician, Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, No. 25 Taiping Street, Luzhou 646000, Sichuan Province, China. zj000718@yeah.net
Received: July 8, 2021
Peer-review started: July 8, 2021
First decision: August 18, 2021
Revised: August 31, 2021
Accepted: September 16, 2021
Article in press: September 16, 2021
Published online: November 26, 2021
Core Tip

Core Tip: Glioblastoma is common to have in situ recurrence and intracranial metastasis, while extracranial metastasis is rare, and extracranial multiorgan metastasis is extremely rare. We reported a case of extracranial multiple organ metastasis of glioblastoma, reviewed relevant literature, and discussed the related mechanism and treatment plan. This report may provide more possibilities for the related mechanism and treatment of extracranial metastasis of glioblastoma.