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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 6, 2021; 9(19): 5238-5244
Published online Jul 6, 2021. doi: 10.12998/wjcc.v9.i19.5238
Published online Jul 6, 2021. doi: 10.12998/wjcc.v9.i19.5238
Liver metastasis as the initial clinical manifestation of sublingual gland adenoid cystic carcinoma: A case report
Xiao-Hong Li, Yu-Tao Zhang, Department of Pathology, The First People’s Hospital of Zigong, Zigong 643099, Sichuan Province, China
Hao Feng, Department of Radiology, The First People’s Hospital of Zigong, Zigong 643099, Sichuan Province, China
Author contributions: Li XH and Zhang YT contributed equally to this work; Li XH and Zhang YT collected the clinicopathologic data and wrote the manuscript; Feng H collected and analyzed the radiological data; all authors have read and approve the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yu-Tao Zhang, MA, Chief Physician, Department of Pathology, The First People’s Hospital of Zigong, No. 42 Shangyihao Street, Zigong 643099, Sichuan Province, China. bondyzyt1999@163.com
Received: January 7, 2021
Peer-review started: January 7, 2021
First decision: February 11, 2021
Revised: February 15, 2021
Accepted: March 8, 2021
Article in press: March 8, 2021
Published online: July 6, 2021
Peer-review started: January 7, 2021
First decision: February 11, 2021
Revised: February 15, 2021
Accepted: March 8, 2021
Article in press: March 8, 2021
Published online: July 6, 2021
Core Tip
Core Tip: This is a report of a very rare case of liver metastasis as the initial clinical manifestation of sublingual gland adenoid cystic carcinoma (ACC). It has not been described in the English literature until now. We describe this case in detail, with a review of the clinical and pathological characteristics, differential diagnosis, and therapy of metastatic salivary gland ACC. Three previous reports and our case confirm that an isolated liver metastasis can be the primary presentation of salivary gland ACC. An MYB-NFIB fusion gene was not detected by fluorescence in situ hybridization in either the primary or metastatic ACC tumor.