Observational Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2022; 10(22): 7808-7824
Published online Aug 6, 2022. doi: 10.12998/wjcc.v10.i22.7808
Complications of chronic pancreatitis prior to and following surgical treatment: A proposal for classification
Marko Murruste, Ülle Kirsimägi, Karri Kase, Tatjana Veršinina, Peep Talving, Urmas Lepner
Marko Murruste, Ülle Kirsimägi, Karri Kase, Tatjana Veršinina, Urmas Lepner, Department of Surgery, Tartu University Hospital, Tartu 50406, Estonia
Peep Talving, Department of Surgery, Board, North Estonia Medical Centre, Tallinn 13419, Estonia
Author contributions: Murruste M, Kirsimägi Ü, Kase K, Veršinina T, Talving P, and Lepner U designed the study; Murruste M, Kirsimägi Ü, Kase K, and Veršinina T performed the study; Murruste M and Kirsimägi Ü produced the statistics and wrote the paper.
Institutional review board statement: The study was reviewed and approved by the University of Tartu (UT REC) Institutional Review Board, No. 291/T-1.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Marko Murruste, MD, Doctor, Surgeon, Department of Surgery, Tartu University Hospital, 8 Puusepa Str, Tartu 50406, Estonia. marko.murruste@kliinikum.ee
Received: January 3, 2022
Peer-review started: January 4, 2022
First decision: March 12, 2022
Revised: March 22, 2022
Accepted: June 13, 2022
Article in press: June 13, 2022
Published online: August 6, 2022
Core Tip

Core Tip: Chronic pancreatitis is frequently associated with complications for which there exists no classification. This study proposes a pathophysiological classification of the complications of chronic pancreatitis (CP) and reports their prevalence in a surgical cohort. We distinguished four groups of complications: Pancreatic duct complications, peripancreatic complications, pancreatic hemorrhages, and pancreatic insufficiency. We believe the proposed classification improves the understanding of CP and could be beneficial for clinical decision making, as it provides an opportunity for more comprehensive judgement on patient’s needs on the one hand, and on the pros and cons of the treatment under consideration, on the other.