Observational Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 6, 2022; 10(16): 5266-5274
Published online Jun 6, 2022. doi: 10.12998/wjcc.v10.i16.5266
Long-term outcomes of high-risk percutaneous coronary interventions under extracorporeal membrane oxygenation support: An observational study
Yi-Xiong Huang, Zheng-Ming Xu, Li Zhao, Yi Cao, Yu Chen, Yi-Gang Qiu, Ying-Ming Liu, Peng-Yu Zhang, Jiang-Chun He, Tian-Chang Li
Yi-Xiong Huang, Medical School of Chinese People’s Liberation Army, Beijing 100853, China
Yi-Xiong Huang, Zheng-Ming Xu, Li Zhao, Yi Cao, Yu Chen, Yi-Gang Qiu, Ying-Ming Liu, Peng-Yu Zhang, Jiang-Chun He, Tian-Chang Li, Department of Cardiology, Sixth Medical Center of Chinese People’s Liberation Army General Hospital, Beijing 100048, China
Author contributions: Huang YX, Chen Y, and Li TC designed the study; Huang YX drafted the manuscript; Cao Y, Qiu YG, Liu YM, and He JC revised it critically for important intellectual content; Xu ZM, Zhao L, and Zhang PY contributed to the analysis and interpretation of data; Li TC, the corresponding author of this manuscript, gave final approval of the manuscript submitted.
Institutional review board statement: The study was reviewed and approved by the Sixth Medical Center of PLA General Hospital Institutional Review Board (Beijing).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: Technical appendix, statistical code, and dataset are available from the corresponding author at itc909@163.com.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tian-Chang Li, MD, PhD, Chief Physician, Department of Cardiology, Sixth Medical Center of Chinese People’s Liberation Army General Hospital, No. 6 Fucheng Road, Beijing 100048, China. itc909@163.com
Received: August 2, 2021
Peer-review started: August 2, 2021
First decision: December 17, 2021
Revised: December 30, 2021
Accepted: April 2, 2022
Article in press: April 2, 2022
Published online: June 6, 2022
Core Tip

Core Tip: High-risk percutaneous coronary intervention (PCI) can result in hemodynamic instability during the perioperative period and is associated with poor outcomes. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) can provide hemodynamic support for patients who undergo high-risk PCI. The main role of VA-ECMO in high-risk PCI is to prevent profound hypotension or low cardiac output episodes and allow sufficient time to achieve optimal and complete revascularization. We present a single-center, observational cohort study of all patients undergoing high-risk PCI supported by VA-ECMO. PCI was successfully performed in 57 patients (93.4%). The in-hospital mortality was 23.0%. The overall survival was 45.9% with a median follow-up time of 38.6 (8.6-62.1) mo. VA-ECMO can be successfully used in patients undergoing high-risk PCI with good long-term survival.