Hou M, Ren YP, Wang R, Lu LX. Early cardiopulmonary resuscitation on serum levels of myeloperoxidase, soluble ST2, and hypersensitive C-reactive protein in acute myocardial infarction patients. World J Clin Cases 2021; 9(34): 10585-10594 [PMID: 35004990 DOI: 10.12998/wjcc.v9.i34.10585]
Corresponding Author of This Article
Lin-Xin Lu, BM BCh, Chief Physician, Department of Emergency, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, No. 99 Longcheng Street, Xiaodian District, Taiyuan 030001, Shanxi Province, China. llx6477@163.com
Research Domain of This Article
Emergency Medicine
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Dec 6, 2021; 9(34): 10585-10594 Published online Dec 6, 2021. doi: 10.12998/wjcc.v9.i34.10585
Early cardiopulmonary resuscitation on serum levels of myeloperoxidase, soluble ST2, and hypersensitive C-reactive protein in acute myocardial infarction patients
Min Hou, Ya-Ping Ren, Rui Wang, Lin-Xin Lu
Min Hou, Rui Wang, Lin-Xin Lu, Department of Emergency, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan 030032, Shanxi Province, China
Min Hou, Ya-Ping Ren, Rui Wang, Lin-Xin Lu, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
Ya-Ping Ren, Department of Cardiology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan 030032, Shanxi Province, China
Author contributions: Hou M and Lu LX analyzed the data and drafted the paper; Wang R revised the chart of the paper; Ren YP and Hou M analyzed the data and revised and finalized the manuscript for publication.
Supported byKey R&D Projects in Shanxi Province, China, No. 201903D321184.
Institutional review board statement: The study was reviewed and approved by the Bethune Hospital in Shanxi Institutional Review Board.
Informed consent statement: All study participants provided informed written consent.
Conflict-of-interest statement: None conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lin-Xin Lu, BM BCh, Chief Physician, Department of Emergency, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, No. 99 Longcheng Street, Xiaodian District, Taiyuan 030001, Shanxi Province, China. llx6477@163.com
Received: July 23, 2021 Peer-review started: July 23, 2021 First decision: August 19, 2021 Revised: August 22, 2021 Accepted: October 14, 2021 Article in press: October 14, 2021 Published online: December 6, 2021
ARTICLE HIGHLIGHTS
Research background
The minimum target of cardiac resuscitation is the restoration of spontaneous circulation.
Research motivation
Effective clinical evaluation of the prognosis of patients with acute myocardial infarction (AMI) after cardiac resuscitation is of great significance.
Research objectives
This study aimed to explore the effect of cardiopulmonary resuscitation (CPR) on the levels of myeloperoxidase (MPO), soluble ST2 (sST2), and hypersensitive C-reactive protein (hs-CRP) in patients with AMI.
Research methods
A total of 54 AMI patients with cardiac arrest who were managed in our hospital were selected as the observation group. Fifty patients with AMI were selected as the control group.
Research results
Serum levels of MPO, sST2, hs-CRP, lactic acid, creatine kinase isoenzyme, and troponin I were significantly higher in the observation group than in the control group (P < 0.05).
Research conclusions
MPO, sST2, hs-CRP, and lactic acid had a certain value in predicting the recovery and prognosis of patients with restoration of spontaneous circulation.
Research perspectives
Further in-depth multi-center research with large samples is recommended.
