Zhu RY, Xiang SQ, Chen DR. Combined lumbar muscle block and perioperative comprehensive patient-controlled intravenous analgesia with butorphanol in gynecological endoscopic surgery. World J Clin Cases 2021; 9(34): 10540-10548 [PMID: 35004985 DOI: 10.12998/wjcc.v9.i34.10540]
Corresponding Author of This Article
Dou-Ren Chen, BM BCh, Chief Pharmacist, Department of Pharmacy, Huai’an Hospital Affiliated to Xuzhou Medical University, No. 60 Huaihai South Road, Huai’an 223002, Jiangsu Province, China. chenqq1789ss@sina.com
Research Domain of This Article
Anesthesiology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Dec 6, 2021; 9(34): 10540-10548 Published online Dec 6, 2021. doi: 10.12998/wjcc.v9.i34.10540
Combined lumbar muscle block and perioperative comprehensive patient-controlled intravenous analgesia with butorphanol in gynecological endoscopic surgery
Rong-Yu Zhu, Si-Qu Xiang, Dou-Ren Chen
Rong-Yu Zhu, Si-Qu Xiang, Department of Anesthesiology, Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi 445000, Hubei Province, China
Dou-Ren Chen, Department of Pharmacy, Huai’an Hospital Affiliated to Xuzhou Medical University, Huai’an 223002, Jiangsu Province, China
Author contributions: Zhu RY and Xiang SQ designed the experiment; Zhu RY and Xiang SQ contributed equally and considered as co-first authors; Chen DR drafted the work; Zhu RY collected the data; Xiang SQ analyzed and interpreted data; Zhu RY and Chen DR wrote the article.
Institutional review board statement: This study was approved by the Central Hospital of Enshi Tujia and Miao Autonomous Prefecture Ethics Committee.
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dou-Ren Chen, BM BCh, Chief Pharmacist, Department of Pharmacy, Huai’an Hospital Affiliated to Xuzhou Medical University, No. 60 Huaihai South Road, Huai’an 223002, Jiangsu Province, China. chenqq1789ss@sina.com
Received: August 6, 2021 Peer-review started: August 6, 2021 First decision: September 1, 2021 Revised: September 8, 2021 Accepted: October 14, 2021 Article in press: October 14, 2021 Published online: December 6, 2021
ARTICLE HIGHLIGHTS
Research background
Laparoscopic surgery has become a common surgical method for clinical treatment of intra-abdominal lesions.
Research motivation
This study explored the role and influence of butorphanol in patient-controlled intravenous analgesia (PCIA) lumbar spine block after general anesthesia gynecological surgery.
Research objectives
To explore the possible application prospect of butorphanol in PCIA lumbar block after general anesthesia gynecological surgery.
Research methods
The investigation was conducted on 120 female patients who underwent laparoscopic surgery in our hospital from May 2017 to May 2020.
Research results
The serum tumor necrosis factor-α levels of the research group 24 h postoperatively were significantly lower than those of the control group (P < 0.05). The levels of serum interleukin-6 and interleukin-8 in the study group 24 h and 48 h postoperatively were significantly lower than those in the control group (P < 0.05).
Research conclusions
PCIA lumbar block with butorphanol after general anesthesia and gynecological surgery can significantly improve the analgesic effect.
Research perspectives
Quadratus lumborum block combined with butorphanol postoperative PCIA has significantly better analgesic effects and may be more widely used.
