Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 6, 2023; 11(16): 3756-3764
Published online Jun 6, 2023. doi: 10.12998/wjcc.v11.i16.3756
Dexmedetomidine-induced anesthesia in elderly patients undergoing hip replacement surgery
Jun-Qing Li, Hao Yuan, Xiao-Qiang Wang, Meng Yang
Jun-Qing Li, Hao Yuan, Xiao-Qiang Wang, Meng Yang, Department of Anesthesiology, Fuyang Hospital Affiliated to Anhui Medical University, Fuyang 236000, Anhui Province, China
Author contributions: Li JQ and Yuan H proposed concepts for this study; Wang XQ and Yang M collected data; Li JQ, Yuan H, and Wang XQ contributed to formal analysis; Li JQ and Yang M contributed to the survey; Li JQ, Yuan H, and Yang M contributed to this method; Li JQ, Yuan H, Wang XQ, and Yang M supervised the study; Li JQ validated this study; Yuan H and Wang XQ contributed to the visualization of research; Li JQ and Yuan H initially drafted this manuscript; Li JQ, Yuan H, Wang XQ, and Yang M reviewed and edited the manuscript.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Committee of the First Hospital Affiliated to Anhui Medical University.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: We declare that there are no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jun-Qing Li, MD, Attending Doctor, Department of Anesthesiology, Fuyang Hospital of Anhui Medical University, No. 99 Huangshan Road, Fuyang Hefei Modern Industrial Park, Yingzhou District, Fuyang 236000, Anhui Province, China. lijunqing005@126.com
Received: March 13, 2023
Peer-review started: March 13, 2023
First decision: March 28, 2023
Revised: April 13, 2023
Accepted: April 24, 2023
Article in press: April 24, 2023
Published online: June 6, 2023
ARTICLE HIGHLIGHTS
Research background

A femoral neck fracture is a common and frequently-occurring disease in orthopedics, with a high incidence in the elderly population. For elderly patients with a femoral neck fracture, due to their older age and more basic diseases, the difficulty of anesthesia and surgery is increased. General anesthesia can easily induce complications such as cognitive dysfunction, which is not conducive to postoperative recovery.

Research motivation

This study analyzed the anesthetic effect of dexmedetomidine in elderly patients undergoing hip replacement.

Research objectives

This study aimed to provide a reference for the prognosis and anesthesia of clinical-related surgeries.

Research methods

A total of 98 elderly patients undergoing hip replacement were randomly divided into control group and observation group. Both groups were observed until the patients were discharged. The vital signs, serum inflammatory factors and renal function indexes of the two groups were compared before, during and 6 h after operation.

Research results

Dexmedetomidine has good safety and good anesthetic effect.

Research conclusions

Dexmedetomidine can effectively improve the vital signs of elderly patients undergoing hip replacement, reduce the body's inflammatory response, reduce renal function damage, and promote postoperative recovery. At the same time, it has good safety and good anesthetic effect.

Research perspectives

This study indicates that diazepam has good application prospects in elderly patients undergoing hip replacement surgery. Future research can further explore the anesthesia effect and safety of diazepam, search for more optimized anesthesia plans, and improve the success rate of hip replacement surgery in elderly patients.