Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2020; 8(7): 1271-1277
Published online Apr 6, 2020. doi: 10.12998/wjcc.v8.i7.1271
Spinal intraosseous schwannoma without spinal canal and neuroforamina involvement: A case report
Zhong-Qi Xu, Ping Zhang, Zhi-Hong Zhong, Wei Zhou, Hao-Tao Yu
Zhong-Qi Xu, Ping Zhang, Zhi-Hong Zhong, Wei Zhou, Hao-Tao Yu, Department of Orthopedics, The Third Affiliated Hospital of Guangzhou Medical University, Guanzhou 510000, Guandong Province, China
Author contributions: Zhang P and Xu ZQ conceived the report; Xu ZQ wrote the first draft with input from all authors; Zhong ZH and Zhou W analyzed and interpreted the patient data regarding the disease; Yu HT performed the histological examination of the lesions; all authors read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ping Zhang, PhD, Doctor, Department of Orthopedics, The Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou 510000, Guangdong Province, China. 644459349@qq.com
Received: December 9, 2019
Peer-review started: December 9, 2019
First decision: January 7, 2020
Revised: January 13, 2020
Accepted: March 9, 2020
Article in press: March 9, 2020
Published online: April 6, 2020
Abstract
BACKGROUND

Spinal intraosseous schwannomas (SIS) are rare, and as yet have not been fully described in the literature. The first case of SIS was reported in 1971, and 24 cases of SIS have been reported so far. However, including the present case, there are only seven cases without spinal canal and neuroforamina involvement.

CASE SUMMARY

A 56-year-old man presented with a history of neck pain for 2 years. An obvious osteolytic destruction of the seventh cervical (C7) vertebra was observed on imaging examination. Magnetic resonance imaging of the cervical spine showed space-occupying lesions in the C7 vertebra, and destruction of the anterior cortex of the vertebra. The lesions had an exophytic component that extended from the C7 vertebra into the soft tissue on the front side. The foramen transversarium on both sides were intact. The patient underwent surgical biopsy and focal excision of the C7 lesion. The diagnosis of “schwannoma” was verified by postoperative pathological examinations. In a review of the literature, this is the seventh case of SIS without spinal canal and neuroforamina involvement, and the third reported case of type VIII SIS. We discussed our case with respect to reported classification characteristics of SIS.

CONCLUSION

SIS is a very rare tumor. We report a rare case that may be important for further classification of osteo-schwannoma. The establishment of a complete disease classification is of high importance for the treatment and prognosis of this disease. Thus, more basic studies and retrospective analysis of related cases are necessary.

Keywords: Spinal intraosseous schwannoma, Neurilemmoma, Spinal tumor, Classification, Case report, Cervical

Core tip: Intraosseous schwannomas are extremely rare, accounting for < 0.2% of primary bone tumors. Spinal intraosseous schwannomas (SIS) are even rarer. We present a rare case of SIS of the seventh cervical (C7) vertebra in a 56-year-old man presenting with a history of neck pain for 2 years. An obvious osteolytic destruction of the C7 vertebra was observed on imaging examination. The patient underwent surgical biopsy and focal excision of the C7 lesion. The diagnosis of “schwannoma” was verified by postoperative pathological examinations. In a review of the literature, this is the seventh case of SIS without spinal canal and neuroforamina involvement, and the third case of type VIII SIS. It is important for further classification of osteo-schwannoma.