Ma YB, Hu J, Duan YF. Acute pancreatitis connected with hypercalcemia crisis in hyperparathyroidism: A case report. World J Clin Cases 2019; 7(16): 2367-2373 [PMID: 31531333 DOI: 10.12998/wjcc.v7.i16.2367]
Corresponding Author of This Article
Yun-Fei Duan, MD, Doctor, Department of Hepatobiliary Surgery, The First People’s Hospital of Changzhou, No. 185, Juqian Street, Changzhou 213003, Jiangsu Province, China. 897787224@qq.com
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Aug 26, 2019; 7(16): 2367-2373 Published online Aug 26, 2019. doi: 10.12998/wjcc.v7.i16.2367
Acute pancreatitis connected with hypercalcemia crisis in hyperparathyroidism: A case report
Yi-Bo Ma, Jun Hu, Yun-Fei Duan
Yi-Bo Ma, Department of B-mode Ultrasound, The First People’s Hospital of Changzhou, Changzhou 213003, Jiangsu Province, China
Jun Hu, Yun-Fei Duan, Department of Hepatobiliary Surgery, The First People’s Hospital of Changzhou, Changzhou 213003, Jiangsu Province, China
Author contributions: Duan YF designed the research and diagnosed and treated the patient; Hu J and Ma YB collected the patient’s clinical data and wrote the paper.
Informed consent statement: Informed consent was obtained from the patient.
Conflict-of-interest statement: There is no conflict of interest related to this report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2013), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Yun-Fei Duan, MD, Doctor, Department of Hepatobiliary Surgery, The First People’s Hospital of Changzhou, No. 185, Juqian Street, Changzhou 213003, Jiangsu Province, China. 897787224@qq.com
Telephone: +86-519-868871341
Received: April 24, 2019 Peer-review started: April 24, 2019 First decision: June 3, 2019 Revised: June 11, 2019 Accepted: June 26, 2019 Article in press: June 27, 2019 Published online: August 26, 2019
Abstract
BACKGROUND
The association between primary hyperparathyroidism (PHPT) and acute pancreatitis is rarely reported. Here we describe the process of acute pancreatitis-mediated PHPT induced by hypercalcemia in a male patient. Hypercalcemia induced by undiagnosed PHPT may be the causative factor in recurrent acute pancreatitis.
CASE SUMMARY
We report a case of hypercalcemia-induced acute pancreatitis caused by a functioning parathyroid adenoma in a 57-year-old man. The patient initially experienced a series of continuous gastrointestinal symptoms including abdominal distension, abdominal pain, nausea, vomiting, electrolyte disturbance, renal dysfunction, and acute pancreatitis. Due to prolonged hypercalcemia, the patient subsequently underwent surgical resection of the parathyroid adenoma. Two weeks after surgery, his serum calcium, amylase, and lipase concentrations were normal. The patient had a good recovery after a series of other relevant therapies.
CONCLUSION
Acute pancreatitis as the first presentation is a rare clinical symptom caused by PHPT-induced hypercalcemia.
Core tip: Acute pancreatitis as the first presentation is a rare clinical symptom caused by primary hyperparathyroidism-induced hypercalcemia. Surgical
resection remains the only safe and curative treatment option available. Therefore, the possibility of hyperparathyroidism disease needs to be considered when acute pancreatitis occurs.
