Kumar R. Esthesioneuroblastoma: Multimodal management and review of literature. World J Clin Cases 2015; 3(9): 774-778 [PMID: 26380824 DOI: 10.12998/wjcc.v3.i9.774]
Corresponding Author of This Article
Ritesh Kumar, Assistant Professor, Department of Radiotherapy, BRAIRCH, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India. riteshkr9@gmail.com
Research Domain of This Article
Oncology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Sep 16, 2015; 3(9): 774-778 Published online Sep 16, 2015. doi: 10.12998/wjcc.v3.i9.774
Esthesioneuroblastoma: Multimodal management and review of literature
Ritesh Kumar
Ritesh Kumar, Department of Radiotherapy, BRAIRCH, All India Institute of Medical Sciences, New Delhi 110029, India
Author contributions: Kumar R contributed to concept and design literature review.
Conflict-of-interest statement: The authors declare no potential conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ritesh Kumar, Assistant Professor, Department of Radiotherapy, BRAIRCH, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India. riteshkr9@gmail.com
Telephone: +91-981-4056719
Received: April 22, 2015 Peer-review started: April 22, 2015 First decision: May 19, 2015 Revised: July 8, 2015 Accepted: July 24, 2015 Article in press: July 27, 2015 Published online: September 16, 2015
Abstract
Esthesioneuroblastoma (ENB) is a rare malignant neoplasm arising from the olfactory neuroepithelium. ENB constitutes only 3% of all malignant intranasal neoplasm. Because of the rarity, the number of patients of ENB treated in individual departments is small. Most of these patients presents in locally advanced stages and require multimodality treatment in form of surgery, chemotherapy and radiotherapy. Multimodality approach with a risk-adapted strategy is required to achieve good control rates while minimizing treatment related toxicity.
Core tip: This article is a comprehensive review of literature of a rare and aggressive neoplasm. This article outlines the various newer details of diagnosis, staging and treatment aspects of esthesioneuroblastoma (ENB). The importance of multimodality approach in management of ENB is reviewed in detail.
