Zhang JY, Ding JM, Zhou Y, Jing X. Nine-year survival of a 60-year-old woman with locally advanced pancreatic cancer under repeated open approach radiofrequency ablation: A case report. World J Clin Cases 2022; 10(32): 11845-11852 [PMID: 36405299 DOI: 10.12998/wjcc.v10.i32.11845]
Corresponding Author of This Article
Xiang Jing, MD, Professor, Department of Ultrasound, Tianjin Institute of Hepatobiliary Disease, Tianjin Key Laboratory of Artificial Cell, Artificial Cell Engineering Technology Research Center of Public Health Ministry, Tianjin Third Central Hospital, No. 83 Jintang Highway, Tianjin 300170, China. dr.jingxiang@aliyun.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Nov 16, 2022; 10(32): 11845-11852 Published online Nov 16, 2022. doi: 10.12998/wjcc.v10.i32.11845
Nine-year survival of a 60-year-old woman with locally advanced pancreatic cancer under repeated open approach radiofrequency ablation: A case report
Jia-Yi Zhang, Jian-Min Ding, Yan Zhou, Xiang Jing
Jia-Yi Zhang, Department of Ultrasound, The Third Central Clinical College of Tianjin Medical University, Tianjin 300170, China
Jian-Min Ding, Yan Zhou, Xiang Jing, Department of Ultrasound, Tianjin Institute of Hepatobiliary Disease, Tianjin Key Laboratory of Artificial Cell, Artificial Cell Engineering Technology Research Center of Public Health Ministry, Tianjin 300170, China
Author contributions: Zhang JY and Ding JM designed the research study; Zhou Y performed the research; Jing X contributed new reagents and analytic tools; Zhang JY, Ding JM, Zhou Y and Jing X analyzed the data and wrote the manuscript; all authors have read and approve the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors report no relevant conflict of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiang Jing, MD, Professor, Department of Ultrasound, Tianjin Institute of Hepatobiliary Disease, Tianjin Key Laboratory of Artificial Cell, Artificial Cell Engineering Technology Research Center of Public Health Ministry, Tianjin Third Central Hospital, No. 83 Jintang Highway, Tianjin 300170, China. dr.jingxiang@aliyun.com
Received: April 13, 2022 Peer-review started: April 13, 2022 First decision: May 30, 2022 Revised: June 18, 2022 Accepted: October 12, 2022 Article in press: October 12, 2022 Published online: November 16, 2022
Abstract
BACKGROUND
Radiofrequency ablation (RFA) is gaining popularity as an additional therapy for pancreatic ductal adenocarcinoma. RFA appears to be an attractive treatment option for patients with unresectable, locally advanced and nonmetastatic pancreatic cancer.
CASE SUMMARY
A 60-year-old woman with 2 mo intermittent upper abdominal pains was admitted to hospital. She had undergone radical gastrectomy (Billroth II) for gastric antral cancer. Contrast-enhanced computed tomography (CECT) and abdominal ultrasound displayed a primary tumor in the neck of the pancreas. Pathological examination showed that the lesion was a pancreatic ductal adenocarcinoma. According to the results of the imaging, open approach RFA was selected to treat the primary tumor. Eight months later, CECT follow-up revealed local recurrence of the tumor, and another open RFA was performed. Although there is evidence that RFA for recurrence of other cancers such as hepatocellular carcinoma may prolong patient survival, it remains unclear whether repeat RFA for local recurrence of pancreatic cancer is feasible. The patient continued to enjoy 9 years of life following the first RFA.
CONCLUSION
RFA of locally advanced, nonresectable, nonmetastatic, pancreatic tumor is characterized by feasibility-based treatment giving rise to tumor reduction based on improvement of quality of life.
Core Tip: A 60-year-old woman who had previously undergone radical gastrectomy (Billroth II) for gastric antral cancer was found to have a primary tumor on the neck of the pancreas. Pathological examination showed that the lesion was pancreatic ductal adenocarcinoma. Open approach radiofrequency ablation (RFA) was selected to treat the primary tumor. A local recurrent tumor was discovered in the follow-up contrast-enhanced computed tomography after 8 mo with the performance of another open RFA. The patient still enjoys her 9-year survival following the first RFA. It is promising that some cases still have long-term survival based on repeated open RFA.
