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World J Clin Cases. Oct 26, 2022; 10(30): 10862-10866
Published online Oct 26, 2022. doi: 10.12998/wjcc.v10.i30.10862
New-onset diabetes secondary to acute pancreatitis: An update
Xian-Qiang Yu, Qian Zhu
Xian-Qiang Yu, Department of General Surgery, Women's and Children’s Hospital Affiliated to Qingdao University, Qingdao 266034, Shandong Province, China
Qian Zhu, Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei Province, China
Author contributions: Yu XQ and Zhu Q completed the design and writing of the paper; Yu XQ participated in the overall design and revision of the paper.
Conflict-of-interest statement: All authors have no conflicts ofinterest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xian-Qiang Yu, PhD, Doctor, Department of General Surgery, Women's and Children's Hospital affiliated to Qingdao University, No. 6 Tongfu Road, Shibei District, Qingdao 266034, Shandong Province, China. yuxianqiang302@126.com
Received: July 15, 2022
Peer-review started: July 15, 2022
First decision: August 20, 2022
Revised: August 27, 2022
Accepted: September 16, 2022
Article in press: September 16, 2022
Published online: October 26, 2022
Abstract

Diabetes is a condition of persistent hyperglycemia caused by the endocrine disorder of the pancreas. Therefore, all pancreatic diseases have the risk of diabetes. In particular, increasing attention has been paid recently to new-onset diabetes secondary to acute pancreatitis (AP). The complications of secondary diabetes have caused a lot of trouble for patients and have garnered increasing attention. At present, the pathophysiological mechanism of new-onset diabetes caused by AP is not clear. This review summarizes the current understanding of new-onset diabetes secondary to AP.

Keywords: Acute pancreatitis, New-onset diabetes, β-cell, Hyperglycemia

Core Tip: Increasing attention has been paid recently to new-onset diabetes secondary to acute pancreatitis (AP). The complications of secondary diabetes have caused a lot of trouble to patients and have garnered increasing attention. This review summarizes the current understanding of new-onset diabetes secondary to AP.