World health dilemmas: Orphan and rare diseases, orphan drugs and orphan patients

Table 2 The largest health care companies in the world based on annual revenues

Rank	Company	Country	Total annual revenue(USD billions)
1	Johnson and Johnson	United States	61.90
2	Pfizer	United States	50.01
3	Roche	Switzerland	47.35
4	GlaxoSmithKline	United Kingdom	45.83
5	Novartis	Switzerland	44.27
6	Sanofi	France	41.99
7	Astra Zeneca	United Kingdom/Sweden	32.81
8	Abbott Laboratories	United States	30.76
9	Merck and Co.	United States	27.43
10	Bayer HealthCare	Germany	22.30
11	Eli Lilly	United States	21.84
12	Bristol-Myers Squibb	United States	18.81

The companies were ranked by revenue as of March 2010 according to their released 2009 annual reports.