Salivary glutathione peroxidase-1 levels in periodontitis

doi:10.5662/wjm.v16.i3.121596

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World Journal of Methodology

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2222-0682

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World J Methodol. Sep 20, 2026; 16(3): 121596
Published online Sep 20, 2026. doi: 10.5662/wjm.v16.i3.121596

Table 2 Comparisons between subjects without and with periodontitis, n (%)

	Subjects without periodontitis (n = 86)	Subjects with periodontitis (n = 57)	P value
Gender female	64 (74.4)	36 (63.2)	0.19
Age (years) - median (P25-P75)	35 (20-43)	59 (51-68)	< 0.001
Arterial hypertension	4 (4.7)	17 (29.8)	< 0.001
Cardiovascular disease	0	4 (7.0)	0.02
Hypercholesterolemia	2 (2.3)	2 (3.5)	0.99
Diabetes mellitus	0	3 (5.3)	0.06
Rheumatoid arthritis	1 (1.2)	3 (5.3)	0.30
Metrotexate for rheumatoid arthritis	1 (1.2)	0	0.99
Immunosupressive therapy	1 (1.2)	1 (1.8)	0.99
Radiotherapy	0	1 (1.8)	0.40
Body mass index (kg/m²) - median (P25-P75)	24.6 (22.4-26.6)	24.8 (22.5-27.6)	0.66
Obesity	11 (12.8)	8 (14.0)	0.99
Never smoker	68 (79.1)	25 (43.9)	< 0.001
Coffee	66 (76.7)	50 (87.7)	0.13
Tea	22 (25.6)	3 (5.3)	0.001
Alcohol	34 (39.5)	30 (52.6)	0.17
Salivary GPx-1 levels (pg/mL) - median (P25-P75)	1511 (887-2024)	924 (324-1252)	< 0.001
Salivary GPx-1 levels < 1214 pg/mL	26 (30.2)	42 (73.7)	< 0.001

GPx-1: Glutathione peroxidase-1.

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Citation: Lorente L, Hernández Marrero E, Abreu-Gonzalez P, Lorente Martín AD, Lorente Martín M, Marrero González MJ, Hernández Marrero C, Hernández Marrero O, Jiménez A, Hernández Padilla CM. Salivary glutathione peroxidase-1 levels in periodontitis. World J Methodol 2026; 16(3): 121596
URL: https://www.wjgnet.com/2222-0682/full/v16/i3/121596.htm
DOI: https://dx.doi.org/10.5662/wjm.v16.i3.121596

Lorente L, Hernández Marrero E, Abreu-Gonzalez P, Lorente Martín AD, Lorente Martín M, Marrero González MJ, Hernández Marrero C, Hernández Marrero O, Jiménez A, Hernández Padilla CM. Salivary glutathione peroxidase-1 levels in periodontitis. World J Methodol 2026; 16(3): 121596 [PMID: 42625959 DOI: 10.5662/wjm.v16.i3.121596]

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