Pancreatic nerves across species: Anatomical and functional disparities and their metabolic ramifications

doi:10.5662/wjm.118207

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World Journal of Methodology

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2222-0682

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World J Methodol. Sep 20, 2026; 16(3): 118207
Published online Sep 20, 2026. doi: 10.5662/wjm.118207

Table 1 Summary of rodent pancreatic innervation features

Feature	Mouse	Rat
Nerve distribution	Clustered around vessels/lymphoid structures	Diffuse, regional heterogeneity
Key structural feature	Peri-islet nerve sheath	Absent
Nerve density (head/tail)	0.15%/0.02% tissue area	Head > tail (no exact values)
Sympathetic targets	Islet alpha/delta cells, vasculature	Islet alpha cells, vasculature

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Citation: Zhuang SY, Xu LJ, Yang HX, Yang QW, Chen G, Xu B, Yu Z, Liu Y, Xu TC. Pancreatic nerves across species: Anatomical and functional disparities and their metabolic ramifications. World J Methodol 2026; 16(3): 118207
URL: https://www.wjgnet.com/2222-0682/full/v16/i3/118207.htm
DOI: https://dx.doi.org/10.5662/wjm.118207

Zhuang SY, Xu LJ, Yang HX, Yang QW, Chen G, Xu B, Yu Z, Liu Y, Xu TC. Pancreatic nerves across species: Anatomical and functional disparities and their metabolic ramifications. World J Methodol 2026; 16(3): 118207 [DOI: 10.5662/wjm.118207]

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