Comparative effectiveness of parenteral anticoagulants (fondaparinux, argatroban, bivalirudin) in heparin-induced thrombocytopenia: A systematic review

doi:10.5662/wjm.v16.i2.113265

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World Journal of Methodology

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2222-0682

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World J Methodol. Jun 20, 2026; 16(2): 113265
Published online Jun 20, 2026. doi: 10.5662/wjm.v16.i2.113265

Table 3 Key clinical outcomes summary

Agent	Studies (n)	Thrombotic events (%)	Major bleeding (%)	Mortality (%)
Fondaparinux	4	0-15.4	5.1-11.1	5.9-9.3
Argatroban	6	5.9-21.7	5.9-14.5	0-21.7
Bivalirudin	3	7.5-16.9	7.8-15.8	12.4-20.0
Overall range	16	0-30	5-15	0-22

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Citation: Rehman A, Abid M, Jamil H, Siddique S, Parkash S, Nasrullah F, Sapna F, Lohana B, Lohana K, Jawed I, Tufail M, Sharaf MS. Comparative effectiveness of parenteral anticoagulants (fondaparinux, argatroban, bivalirudin) in heparin-induced thrombocytopenia: A systematic review. World J Methodol 2026; 16(2): 113265
URL: https://www.wjgnet.com/2222-0682/full/v16/i2/113265.htm
DOI: https://dx.doi.org/10.5662/wjm.v16.i2.113265

Rehman A, Abid M, Jamil H, Siddique S, Parkash S, Nasrullah F, Sapna F, Lohana B, Lohana K, Jawed I, Tufail M, Sharaf MS. Comparative effectiveness of parenteral anticoagulants (fondaparinux, argatroban, bivalirudin) in heparin-induced thrombocytopenia: A systematic review. World J Methodol 2026; 16(2): 113265 [PMID: 42058815 DOI: 10.5662/wjm.v16.i2.113265]

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